1 |
Xie DL, Meyers R and Homandberg GA (1992) Fibronectin fragments in osteoarthritic synovial fluid. J Rheumatol 19, 1448-1452
|
2 |
Homandberg GA and Hui F (1996) Association of proteoglycan degradation with catabolic cytokine and stromelysin release from cartilage cultured with fibronectin fragments. Arch Biochem Biophys 334, 325-331
DOI
|
3 |
Pichika R and Homandberg GA (2004) Fibronectin fragments elevate nitric oxide (NO) and inducible NO synthetase (iNOS) levels in bovine cartilage and iNOS inhibitors block fibronectin fragment mediated damage and promote repair. Inflamm Res 53, 405-412
DOI
|
4 |
Wu J, Zhang Y, Xin Z and Wu X (2015) The crosstalk between TLR2 and NOD2 in Aspergillus fumigatus keratitis. Mol Immunol 64, 235-243
DOI
|
5 |
Ko R and Lee SY (2016) Glycogen synthase kinase 3beta in Toll-like receptor signaling. BMB Rep 49, 305-310
DOI
|
6 |
Basu M, Paichha M, Swain B et al (2015) Modulation of TLR2, TLR4, TLR5, NOD1 and NOD2 receptor gene expressions and their downstream signaling molecules following thermal stress in the Indian major carp catla (Catla catla). 3 Biotech 5, 1021-1030
DOI
|
7 |
Seong SY and Matzinger P (2004) Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses. Nat Rev Immunol 4, 469-478
DOI
|
8 |
Hwang HS, Park SJ, Cheon EJ, Lee MH and Kim HA (2015) Fibronectin fragment-induced expression of matrix metalloproteinases is mediated by MyD88-dependent TLR-2 signaling pathway in human chondrocytes. Arthritis Res Ther 17, 320
DOI
|
9 |
Xu J, Jiang C, Zhu W et al (2015) NOD2 pathway via RIPK2 and TBK1 is involved in the aberrant catabolism induced by T-2 toxin in chondrocytes. Osteoarthritis Cartilage 23, 1575-1585
DOI
|
10 |
Su SL, Yang HY, Lee CH, Huang GS, Salter DM and Lee HS (2012) The (-1486T/C) promoter polymorphism of the TLR-9 gene is associated with end-stage knee osteoarthritis in a Chinese population. J Orthop Res 30, 9-14
DOI
|
11 |
Yang HY, Lee HS, Lee CH et al (2013) Association of a functional polymorphism in the promoter region of TLR-3 with osteoarthritis: a two-stage case-control study. J Orthop Res 31, 680-685
DOI
|
12 |
Scanzello CR and Goldring SR (2012) The role of synovitis in osteoarthritis pathogenesis. Bone 51, 249-257
DOI
|
13 |
Hasegawa M, Fujimoto Y, Lucas PC et al (2008) A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation. EMBO J 27, 373-383
DOI
|
14 |
Borzutzky A, Fried A, Chou J, Bonilla FA, Kim S and Dedeoglu F (2010) NOD2-associated diseases: Bridging innate immunity and autoinflammation. Clin Immunol 134, 251-261
DOI
|
15 |
Elia PP, Tolentino YF, Bernardazzi C and de Souza HS (2015) The role of innate immunity receptors in the pathogenesis of inflammatory bowel disease. Mediators Inflamm 2015, 936193
DOI
|
16 |
Kim H, Lee YD, Kim MK et al (2017) Extracellular S100A4 negatively regulates osteoblast function by activating the NF-kappaB pathway. BMB Rep 50, 97-102
DOI
|
17 |
Boyle JP, Parkhouse R and Monie TP (2014) Insights into the molecular basis of the NOD2 signalling pathway. Open Biol 4, 140178
DOI
|
18 |
Zack MD, Arner EC, Anglin CP, Alston JT, Malfait AM and Tortorella MD (2006) Identification of fibronectin neoepitopes present in human osteoarthritic cartilage. Arthritis Rheum 54, 2912-2922
DOI
|
19 |
Lees S, Golub SB, Last K et al (2015) Bioactivity in an Aggrecan 32-mer Fragment Is Mediated via Toll-like Receptor 2. Arthritis Rheumatol 67, 1240-1249
DOI
|
20 |
Fosang AJ, Last K, Gardiner P, Jackson DC and Brown L (1995) Development of a cleavage-site-specific monoclonal antibody for detecting metalloproteinase-derived aggrecan fragments: detection of fragments in human synovial fluids. Biochem J 310 ( Pt 1), 337-343
DOI
|
21 |
Miller RE, Ishihara S, Tran PB et al (2018) An aggrecan fragment drives osteoarthritis pain through Toll-like receptor 2. JCI Insight 3, e95704
DOI
|
22 |
Strober W, Murray PJ, Kitani A and Watanabe T (2006) Signalling pathways and molecular interactions of NOD1 and NOD2. Nat Rev Immunol 6, 9-20
DOI
|
23 |
Joosten LA, Heinhuis B, Abdollahi-Roodsaz S et al (2008) Differential function of the NACHT-LRR (NLR) members Nod1 and Nod2 in arthritis. Proc Natl Acad Sci U S A 105, 9017-9022
DOI
|
24 |
Vieira SM, Cunha TM, Franca RF et al (2012) Joint NOD2/RIPK2 signaling regulates IL-17 axis and contributes to the development of experimental arthritis. J Immunol 188, 5116-5122
DOI
|
25 |
Heinhuis B, Koenders MI, van de Loo FA et al (2010) IL-32gamma and Streptococcus pyogenes cell wall fragments synergise for IL-1-dependent destructive arthritis via upregulation of TLR-2 and NOD2. Ann Rheum Dis 69, 1866-1872
DOI
|
26 |
Watanabe T, Kitani A, Murray PJ and Strober W (2004) NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses. Nat Immunol 5, 800-808
DOI
|
27 |
Netea MG, Ferwerda G, de Jong DJ et al (2005) Nucleotide-binding oligomerization domain-2 modulates specific TLR pathways for the induction of cytokine release. J Immunol 174, 6518-6523
DOI
|
28 |
van de Loo FA, Kuiper S, van Enckevort FH, Arntz OJ and van den Berg WB (1997) Interleukin-6 reduces cartilage destruction during experimental arthritis. A study in interleukin-6-deficient mice. Am J Pathol 151, 177-191
|
29 |
Kim JR, Yoo JJ and Kim HA (2018) Therapeutics in Osteoarthritis Based on an Understanding of Its Molecular Pathogenesis. Int J Mol Sci 19, 674
DOI
|
30 |
Kapoor M, Martel-Pelletier J, Lajeunesse D, Pelletier JP and Fahmi H (2011) Role of proinflammatory cytokines in the pathophysiology of osteoarthritis. Nat Rev Rheumatol 7, 33-42
DOI
|
31 |
Ospelt C, Brentano F, Jungel A et al (2009) Expression, regulation, and signaling of the pattern-recognition receptor nucleotide-binding oligomerization domain 2 in rheumatoid arthritis synovial fibroblasts. Arthritis Rheum 60, 355-363
DOI
|
32 |
Petterson T, Jendholm J, Mansson A, Bjartell A, Riesbeck K and Cardell LO (2011) Effects of NOD-like receptors in human B lymphocytes and crosstalk between NOD1/NOD2 and Toll-like receptors. J Leukoc Biol 89, 177-187
DOI
|
33 |
Chen G, Shaw MH, Kim YG and Nunez G (2009) NOD-like receptors: role in innate immunity and inflammatory disease. Annu Rev Pathol 4, 365-398
DOI
|
34 |
Kim HA, Cho ML, Choi HY et al (2006) The catabolic pathway mediated by Toll-like receptors in human osteoarthritic chondrocytes. Arthritis Rheum 54, 2152-2163
DOI
|
35 |
Felson DT (2006) Clinical practice. Osteoarthritis of the knee. N Engl J Med 354, 841-848
DOI
|
36 |
Goldring MB (2000) The role of the chondrocyte in osteoarthritis. Arthritis Rheum 43, 1916-1926
DOI
|