1 |
Strano S, Munarriz E, Rossi M et al (2001) Physical interaction with Yes-associated protein enhances p73 transcriptional activity. J Biol Chem 276, 15164-15173
DOI
|
2 |
Del Mare S and Aqeilan RI (2015) Tumor Suppressor WWOX inhibits osteosarcoma metastasis by modulating RUNX2 function. Sci Rep 5, 12959
DOI
|
3 |
Das A, Chendil D, Dey S et al (2001) Ionizing radiation down-regulates p53 protein in primary Egr-1-/- mouse embryonic fibroblast cells causing enhanced resistance to apoptosis. J Biol Chem 276, 3279-3286
DOI
|
4 |
Murakami M, Nakagawa M, Olson EN and Nakagawa O (2005) A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome. Proc Natl Acad Sci U S A 102, 18034-18039
DOI
|
5 |
Derynck R and Zhang YE (2003) Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 425, 577-584
DOI
|
6 |
Varelas X, Sakuma R, Samavarchi-Tehrani P et al (2008) TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal. Nat Cell Biol 10, 837-848
DOI
|
7 |
Varelas X, Samavarchi-Tehrani P, Narimatsu M et al (2010) The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-beta-SMAD pathway. Dev Cell 19, 831-844
DOI
|
8 |
Jacquemin P, Sapin V, Alsat E, Evain-Brion D, Dolle P and Davidson I (1998) Differential expression of the TEF family of transcription factors in the murine placenta and during differentiation of primary human trophoblasts in vitro. Dev Dyn 212, 423-436
DOI
|
9 |
Li Z, Zhao B, Wang P et al (2010) Structural insights into the YAP and TEAD complex. Genes Dev 24, 235-240
DOI
|
10 |
Chen L, Loh PG and Song H (2010) Structural and functional insights into the TEAD-YAP complex in the Hippo signaling pathway. Protein Cell 1, 1073-1083
DOI
|
11 |
Zhao B, Ye X, Yu J et al (2008) TEAD mediates YAP-dependent gene induction and growth control. Genes Dev 22, 1962-1971
DOI
|
12 |
Mo JS, Meng Z, Kim YC et al (2015) Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway. Nat Cell Biol 17, 500-510
DOI
|
13 |
Zhao B, Lei QY and Guan K L (2008) The Hippo-YAP pathway: new connections between regulation of organ size and cancer. Curr Opin Cell Biol 20, 638-646
DOI
|
14 |
Zhou Y, Huang T Cheng AS, Yu J, Kang W and To KF (2016) The TEAD Family and Its Oncogenic Role in Promoting Tumorigenesis. Int J Mol Sci 17, 1-15
|
15 |
Hiemer SE, Szymaniak AD and Varelas X (2014) The transcriptional regulators TAZ and YAP direct transforming growth factor beta-induced tumorigenic phenotypes in breast cancer cells. J Biol Chem 289, 13461-13474
DOI
|
16 |
Rashidian J, Le Scolan E, Ji X et al (2015) Ski regulates Hippo and TAZ signaling to suppress breast cancer progression. Sci Signal 8, ra14
DOI
|
17 |
Kaneko KJ and DePamphilis ML (1998) Regulation of gene expression at the beginning of mammalian development and the TEAD family of transcription factors. Dev Genet 22, 43-55
DOI
|
18 |
You B, Yang YL, Xu Z et al (2015) Inhibition of ERK1/2 down-regulates the Hippo/YAP signaling pathway in human NSCLC cells. Oncotarget 6, 4357-4368
|
19 |
Nguyen LT, Tretiakova MS, Silvis MR et al (2015) ERG Activates the YAP1 Transcriptional Program and Induces the Development of Age-Related Prostate Tumors. Cancer Cell 27, 797-808
DOI
|
20 |
Chan LH, Wang W, Yeung W, Deng Y, Yuan P and Mak KK (2014) Hedgehog signaling induces osteosarcoma development through Yap1 and H19 overexpression. Oncogene 33, 4857-4866
DOI
|
21 |
Zhang W, Nandakumar N, Shi Y et al (2014) Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma. Sci Signal 7, ra42
DOI
|
22 |
Cai H and Xu Y (2013) The role of LPA and YAP signaling in long-term migration of human ovarian cancer cells. Cell Commun Signal 11, 31
DOI
|
23 |
Artinian N, Cloninger C, Holmes B, Benavides-Serrato A, Bashir T and Gera J (2015) Phosphorylation of the Hippo Pathway Component AMOTL2 by the mTORC2 Kinase Promotes YAP Signaling, Resulting in Enhanced Glioblastoma Growth and Invasiveness. J Biol Chem 290, 19387-19401
DOI
|
24 |
Yu FX, Luo J, Mo JS et al (2014) Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP. Cancer Cell 25, 822-830
DOI
|
25 |
Serrano I, McDonald PC, Lock F, Muller WJ and Dedhar S (2013) Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase. Nat Commun 4, 2976
|
26 |
Wang J, Park JS, Wei Y et al (2013) TRIB2 acts downstream of Wnt/TCF in liver cancer cells to regulate YAP and C/EBPalpha function. Mol Cell 51, 211-225
DOI
|
27 |
Liu AM, Xu Z and Luk JM (2012) An update on targeting Hippo-YAP signaling in liver cancer. Expert Opin Ther Targets 16, 243-247
DOI
|
28 |
Li C, Srivastava RK, Elmets CA, Afaq F and Athar M (2013) Arsenic-induced cutaneous hyperplastic lesions are associated with the dysregulation of Yap, a Hippo signaling-related protein. Biochem Biophys Res Commun 438, 607-612
DOI
|
29 |
Thongon N, Castiglioni I, Zucal C et al (2016) The GSK3beta inhibitor BIS I reverts YAP-dependent EMT signature in PDAC cell lines by decreasing SMADs expression level. Oncotarget 7, 26551-26566
|
30 |
Pobbati AV and Hong W (2013) Emerging roles of TEAD transcription factors and its coactivators in cancers. Cancer Biol Ther 14, 390-398
DOI
|
31 |
Zawacka-Pankau J, Kostecka A, Sznarkowska A, Hedstrom E and Kawiak A (2010) p73 tumor suppressor protein: a close relative of p53 not only in structure but also in anti-cancer approach? Cell Cycle 9, 720-728
DOI
|
32 |
Basu S, Totty NF, Irwin MS, Sudol M and Downward J (2003) Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis. Mol Cell 11, 11-23
DOI
|
33 |
Strano S, Monti O, Pediconi N et al (2005) The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA Damage. Mol Cell 18, 447-459
DOI
|
34 |
Oka T, Mazack V and Sudol M (2008) Mst2 and Lats kinases regulate apoptotic function of Yes kinaseassociated protein (YAP). J Biol Chem 283, 27534-27546
DOI
|
35 |
Rossi M, De Laurenzi V, Munarriz E et al (2005) The ubiquitin-protein ligase Itch regulates p73 stability. EMBO J 24, 836-848
DOI
|
36 |
Bernassola F, Salomoni P, Oberst A et al (2004) Ubiquitin-dependent degradation of p73 is inhibited by PML. J Exp Med 199, 1545-1557
DOI
|
37 |
Okazaki T, Kageji T, Kuwayama K et al (2012) Upregulation of endogenous PML induced by a combination of interferon-beta and temozolomide enhances p73/YAPmediated apoptosis in glioblastoma. Cancer Lett 323, 199-207
DOI
|
38 |
Cottini F, Hideshima T, Xu C et al (2014) Rescue of Hippo coactivator YAP1 triggers DNA damage-induced apoptosis in hematological cancers. Nat Med 20, 599-606
DOI
|
39 |
Levy D, Adamovich Y, Reuven N and Shaul Y (2008) Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage. Mol Cell 29, 350-361
DOI
|
40 |
Levy D, AdamovichY, Reuven N and Shaul Y (2007) The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73. Cell Death Differ 14, 743-751
DOI
|
41 |
Lapi E, Di Agostino S, Donzelli S et al (2008) PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop. Mol Cell 32, 803-814
DOI
|
42 |
Keshet R, Adler J, Ricardo Lax I et al (2015) c-Abl antagonizes the YAP oncogenic function. Cell Death Differ 22, 935-945
DOI
|
43 |
Rosenbluh J, Nijhawan D, Cox AG et al (2012) beta-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis. Cell 151, 1457-1473
DOI
|
44 |
Zaidi SK, Sullivan AJ, Medina R et al (2004) Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription. EMBO J 23, 790-799
DOI
|
45 |
Omerovic J, Puggioni EM, Napoletano S et al (2004) Ligand-regulated association of ErbB-4 to the transcriptional co-activator YAP65 controls transcription at the nuclear level. Exp Cell Res 294, 469-479
DOI
|
46 |
Haskins JW, Nguyen DX and Stern DF (2014) Neuregulin 1-activated ERBB4 interacts with YAP to induce Hippo pathway target genes and promote cell migration. Sci Signal 7, ra116
DOI
|
47 |
Schuchardt BJ, Bhat V, Mikles DC, McDonald CB, Sudol M and Farooq A (2014) Molecular basis of the binding of YAP transcriptional regulator to the ErbB4 receptor tyrosine kinase. Biochimie 101, 192-202
DOI
|
48 |
Harvey K and Tapon N (2007) The Salvador-Warts-Hippo pathway - an emerging tumour-suppressor network. Nat Rev Cancer 7, 182-191
DOI
|
49 |
Zhao B, Wei X, Li W et al (2007) Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. Genes Dev 21, 2747-2761
DOI
|
50 |
Camargo FD, Gokhale S, Johnnidis JB et al (2007) YAP1 increases organ size and expands undifferentiated progenitor cells. Curr Biol 17, 2054-2060
DOI
|
51 |
Dong J, Feldmann G, Huang J et al (2007) Elucidation of a universal size-control mechanism in Drosophila and mammals. Cell 130, 1120-1133
DOI
|
52 |
Huang J, Wu S, Barrera J, Matthews K and Pan D (2005) The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP. Cell 122, 421-434
DOI
|
53 |
Fang KS, Barker K, Sudol M and Hanafusa H (1994) A transmembrane protein-tyrosine phosphatase contains spectrin-like repeats in its extracellular domain. J Biol Chem 269, 14056-14063
|
54 |
Zhu C, Li L and Zhao B (2015) The regulation and function of YAP transcription co-activator. Acta Biochim Biophys Sin (Shanghai) 47, 16-28
DOI
|
55 |
Komori T, Yagi H, Nomura S et al (1997) Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 89, 755-764
DOI
|
56 |
Otto F, Thornell AP, Crompton T et al (1997) Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell 89, 765-771
DOI
|
57 |
Marzia M, Sims NA, Voit S et al (2000) Decreased c-Src expression enhances osteoblast differentiation and bone formation. J Cell Biol 151, 311-320
DOI
|
58 |
Sudol M, Bork P, Einbond A et al (1995) Characterization of the mammalian YAP (Yes-associated protein) gene and its role in defining a novel protein module, the WW domain. J Biol Chem 270, 14733-14741
DOI
|
59 |
Kanai F, Marignani PA, Sarbassova D et al (2000) TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins. EMBO J 19, 6778-6791
DOI
|
60 |
Saucedo LJ and Edgar BA (2007) Filling out the Hippo pathway. Nat Rev Mol Cell Biol 8, 613-621
DOI
|
61 |
Soriano P, Montgomery C, Geske R and Bradley A (1991) Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell 64, 693-702
DOI
|
62 |
Hong JH, Hwang ES, McManus MT et al (2005) TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. Science 309, 1074-1078
DOI
|
63 |
Li QL, Ito K, Sakakura C et al (2002) Causal relationship between the loss of RUNX3 expression and gastric cancer. Cell 109, 113-124
DOI
|
64 |
Jang JW, Kim MK, Lee YS et al (2017) RAC-LATS1/2 signaling regulates YAP activity by switching between the YAP-binding partners TEAD4 and RUNX3. Oncogene 36, 999-1011
DOI
|
65 |
Zender L, Spector MS, Xue W et al (2006) Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach. Cell 125, 1253-1267
DOI
|
66 |
Grannas K, Arngarden L, Lonn P et al (2015) Crosstalk between Hippo and TGFbeta: Subcellular Localization of YAP/TAZ/Smad Complexes. J Mol Biol 427, 3407-3415
DOI
|
67 |
Barry ER, Morikawa T, Butler BL et al (2013) Restriction of intestinal stem cell expansion and the regenerative response by YAP. Nature 493, 106-110
|
68 |
Morin-Kensicki EM, Boone BN, Howell M et al (2006) Defects in yolk sac vasculogenesis, chorioallantoic fusion, and embryonic axis elongation in mice with targeted disruption of Yap65. Mol Cell Biol 26, 77-87
DOI
|
69 |
Hall CA, Wang R, Miao J et al (2010) Hippo pathway effector Yap is an ovarian cancer oncogene. Cancer Res 70, 8517-8525
DOI
|
70 |
Wang Y, Dong Q, Zhang Q, Li Z, Wang E and Qiu X (2010) Overexpression of yes-associated protein contributes to progression and poor prognosis of non-small-cell lung cancer. Cancer Sci 101, 1279-1285
DOI
|
71 |
Zhou Z, Zhu JS and Xu ZP (2011) RNA interference mediated YAP gene silencing inhibits invasion and metastasis of human gastric cancer cell line SGC-7901. Hepatogastroenterology 58, 2156-2161
|
72 |
Chan SW, Lim CJ, Loo LS, Chong YF, Huang C and Hong W (2009) TEADs mediate nuclear retention of TAZ to promote oncogenic transformation. J Biol Chem 284, 14347-14358
DOI
|
73 |
Yu FX, Zhao B, Panupinthu N et al (2012) Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling. Cell 150, 780-791
DOI
|
74 |
Mo JS, Yu FX, Gong R, Brown JH and Guan KL (2012) Regulation of the Hippo-YAP pathway by proteaseactivated receptors (PARs). Genes Dev 26, 2138-2143
DOI
|
75 |
Liu-Chittenden Y, Huang B, Shim JS et al (2012) Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP. Genes Dev 26, 1300-1305
DOI
|
76 |
Zhao B, Kim J, Ye X, Lai ZC and Guan KL (2009) Both TEAD-binding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein. Cancer Res 69, 1089-1098
|
77 |
Zhang H, Pasolli HA and Fuchs E (2011) Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin. Proc Natl Acad Sci U S A 108, 2270-2275
DOI
|
78 |
Fernandez LA, Squatrito M, Northcott P et al (2012) Oncogenic YAP promotes radioresistance and genomic instability in medulloblastoma through IGF2-mediated Akt activation. Oncogene 31, 1923-1937
DOI
|
79 |
Fujii M, Nakanishi H, Toyoda T et al (2012) Convergent signaling in the regulation of connective tissue growth factor in malignant mesothelioma: TGFbeta signaling and defects in the Hippo signaling cascade. Cell Cycle 11, 3373-3379
DOI
|
80 |
Xia Y, Zhang YL, Yu C, Chang T and Fan HY (2014) YAP/TEAD co-activator regulated pluripotency and chemoresistance in ovarian cancer initiated cells. PLoS One 9, e109575
DOI
|
81 |
Chen L, Chan SW, Zhang X et al (2010) Structural basis of YAP recognition by TEAD4 in the hippo pathway. Genes Dev 24, 290-300
DOI
|
82 |
Fossdal R, Jonasson F, Kristjansdottir GT et al (2004) A novel TEAD1 mutation is the causative allele in Sveinsson's chorioretinal atrophy (helicoid peripapillary chorioretinal degeneration). Hum Mol Genet 13, 975-981
DOI
|
83 |
Kitagawa M (2007) A Sveinsson's chorioretinal atrophyassociated missense mutation in mouse Tead1 affects its interaction with the co-factors YAP and TAZ. Biochem Biophys Res Commun 361, 1022-1026
DOI
|
84 |
Zhang J, Ji JY, Yu M et al (2009) YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway. Nat Cell Biol 11, 1444-1450
DOI
|
85 |
Yang N, Morrison CD, Liu P et al (2012) TAZ induces growth factor-independent proliferation through activation of EGFR ligand amphiregulin. Cell Cycle 11, 2922-2930
DOI
|
86 |
Neto-Silva RM, de Beco S and Johnston LA (2010) Evidence for a growth-stabilizing regulatory feedback mechanism between Myc and Yorkie, the Drosophila homolog of Yap. Dev Cell 19, 507-520
DOI
|
87 |
Komuro A, Nagai M, Navin NE and Sudol M (2003) WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus. J Biol Chem 278, 33334-33341
DOI
|
88 |
Zagurovskaya M, Shareef MM, Das A et al (2009) EGR-1 forms a complex with YAP-1 and upregulates Bax expression in irradiated prostate carcinoma cells. Oncogene 28, 1121-1131
DOI
|
89 |
Qiao Y, Lin SJ, Chen Y et al (2016) RUNX3 is a novel negative regulator of oncogenic TEAD-YAP complex in gastric cancer. Oncogene 35, 2664-2674
DOI
|
90 |
Yagi R, Chen LF, Shigesada K, Murakami Y and Ito Y (1999) A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator. EMBO J 18, 2551-2562
DOI
|
91 |
Ferrigno O, Lallemand F, Verrecchia F et al (2002) Yes-associated protein (YAP65) interacts with Smad7 and potentiates its inhibitory activity against TGF-beta/Smad signaling. Oncogene 21, 4879-4884
DOI
|
92 |
Kurisaki A, Kose S, Yoneda Y, Heldin CH and Moustakas A (2001) Transforming growth factor-beta induces nuclear import of Smad3 in an importin-beta1 and Ran-dependent manner. Mol Biol Cell 12, 1079-1091
DOI
|
93 |
Vassilev A, Kaneko KJ, Shu H, Zhao Y and DePamphilis ML (2001) TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm. Genes Dev 15, 1229-1241
DOI
|
94 |
Xiao JH, Davidson I, Matthes H, Garnier JM and Chambon P (1991) Cloning, expression, and transcriptional properties of the human enhancer factor TEF-1. Cell 65, 551-568
DOI
|
95 |
Aqeilan RI, Kuroki T, Pekarsky Y et al (2004) Loss of WWOX expression in gastric carcinoma. Clin Cancer Res 10, 3053-3058
DOI
|
96 |
Aqeilan RI, Donati V, Gaudio E et al (2007) Association of Wwox with ErbB4 in breast cancer. Cancer Res 67, 9330-9336
DOI
|
97 |
Aqeilan RI, Hassan MQ, de Bruin A et al (2008) The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism. J Biol Chem 283, 21629-21639
DOI
|
98 |
Aqeilan RI, Donati V, Palamarchuk A et al (2005) WW domain-containing proteins, WWOX and YAP, compete for interaction with ErbB-4 and modulate its transcriptional function. Cancer Res 65, 6764-6772
DOI
|