1 |
Knobloch M, Pilz GA, Ghesquiere B et al (2017) A fatty acid oxidation-dependent metabolic shift regulates adult neural stem cell activity. Cell Rep 20, 2144-2155
DOI
|
2 |
Kilbaugh TJ, Lvova M, Karlsson M et al (2015) Peripheral blood mitochondrial DNA as a biomarker of cerebral mitochondrial dysfunction following traumatic brain injury in a porcine model. Ai J, ed. PLoS One 10, e0130927
DOI
|
3 |
Knobloch M, Braun SMG, Zurkirchen L et al (2014) Metabolic control of adult neural stem cell activity by Fasn- dependent lipogenesis. Nature 493, 226-230
|
4 |
Smirnova E, Griparic L, Shurland DL and van der Bliek AM (2001) Dynamin-related protein Drp1 Is required for mitochondrial division in mammalian cells. Mol Biol Cell 12, 2245-2256
DOI
|
5 |
Chen H, Detmer SA, Ewald AJ, Griffin EE, Fraser SE and Chan DC (2003) Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. J Cell Biol 160, 189-200
DOI
|
6 |
Chen H and Chan DC (2004) Mitochondrial dynamics in mammals. In: Schatten GP, ed. Vol 59. Current topics in developmental biology. Academic Press 59, 119-144
|
7 |
Khacho M, Clark A, Svoboda DS et al (2016) Mitochondrial dynamics impacts stem cell identity and fate decisions by regulating a nuclear transcriptional program. Cell Stem Cell 19, 232-247
DOI
|
8 |
Khacho M and Slack RS (2018) Mitochondrial dynamics in the regulation of neurogenesis: From development to the adult brain. Dev Dyn 247, 47-53
DOI
|
9 |
Beckervordersandforth R, Ebert B, Schaffner I et al (2017) Role of mitochondrial metabolism in the control of early lineage progression and aging phenotypes in adult hippocampal neurogenesis. Neuron 93, 560-573 e6
DOI
|
10 |
Alirol E and Martinou JC (2006) Mitochondria and cancer: Is there a morphological connection? Oncogene 25, 4706-4716
DOI
|
11 |
Shin J, Berg DA, Zhu Y et al (2015) Single-cell RNA-seq with waterfall reveals molecular cascades underlying adult neurogenesis. Cell Stem Cell 17, 360-372
DOI
|
12 |
Novello F and McLean P (1968) The pentose phosphate pathway of glucose metabolism. Measurement of the non-oxidative reactions of the cycle. Biochem J 107, 775-791
DOI
|
13 |
Lunt SY and Vander Heiden MG (2011) Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation. Annu Rev Cell Dev Biol 27, 441-464
DOI
|
14 |
Kuznetsov AV, Hermann M, Saks V, Hengster P and Margreiter R (2009) The cell-type specificity of mitochondrial dynamics. Int J Biochem Cell Biol 41, 1928-1939
DOI
|
15 |
Yellen G (2018) Fueling thought: Management of glycolysis and oxidative phosphorylation in neuronal metabolism. J Cell Biol 217, 2235-2246
DOI
|
16 |
Ebrahimi-Fakhari D, Saffari A, Wahlster L et al (2016) Impaired mitochondrial dynamics and mitophagy in neuronal models of tuberous sclerosis complex. Cell Rep 17, 1053-1070
DOI
|
17 |
Telley L, Govindan S, Prados J et al (2016) Sequential transcriptional waves direct the differentiation of newborn neurons in the mouse neocortex. Science 351, 1443-1446
DOI
|
18 |
Marin-Valencia I, Cho SK, Rakheja D et al (2012) Glucose metabolism via the pentose phosphate pathway, glycolysis and Krebs cycle in an orthotopic mouse model of human brain tumors. NMR Biomed 25, 1177-1186
DOI
|
19 |
Fang D, Yan S, Yu Q, Chen D and Yan SS (2016) Mfn2 is required for mitochondrial development and synapse formation in human induced pluripotent stem cells/hiPSC derived cortical neurons. Sci Rep 6, 1-13
DOI
|
20 |
Zheng X, Boyer L, Jin M et al (2016) Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation. Elife 5, 1-25
|
21 |
Agostini M, Romeo F, Inoue S et al (2016) Metabolic reprogramming during neuronal differentiation. Cell Death Differ 23, 1502-1514
DOI
|
22 |
Fortelny N, Overall CM, Pavlidis P and Freue GVC (2017) Can we predict protein from mRNA levels? Nature 547, E19-E20
DOI
|
23 |
Liu Y, Beyer A and Aebersold R (2016) On the dependency of cellular protein levels on mRNA Abundance. Cell 165, 535-550
DOI
|
24 |
Chen Y and Sheng ZH (2013) Kinesin-1-syntaphilin coupling mediates activity-dependent regulation of axonal mitochondrial transport. J Cell Biol 202, 351-364
DOI
|
25 |
MacAskill AF, Rinholm JE, Twelvetrees AE et al (2009) Miro1 Is a calcium sensor for glutamate receptordependent localization of mitochondria at synapses. Neuron 61, 541-555
DOI
|
26 |
Xu X, Duan S, Yi F, Ocampo A, Liu GH and Izpisua Belmonte JC (2013) Mitochondrial regulation in pluripotent stem cells. Cell Metab 18, 325-332
DOI
|
27 |
Zhang H, Menzies KJ and Auwerx J (2018) The role of mitochondria in stem cell fate and aging. Development 145, dev143420
DOI
|
28 |
Teslaa T and Teitell MA (2015) Pluripotent stem cell energy metabolism: an update. EMBO J 34, 138-153
DOI
|
29 |
Lees JG, Gardner DK and Harvey AJ (2017) Pluripotent stem cell metabolism and mitochondria: beyond ATP. Stem Cells Int 2017, 2874283
|
30 |
Suomalainen A and Battersby BJ (2018) Mitochondrial diseases: The contribution of organelle stress responses to pathology. Nat Rev Mol Cell Biol 19, 77-92
DOI
|
31 |
Ott M, Amunts A and Brown A (2016) Organization and regulation of mitochondrial protein synthesis. Annu Rev Biochem 85, 77-101
DOI
|
32 |
Roger AJ, Munoz-Gomez SA and Kamikawa R (2017) The origin and diversification of mitochondria. Curr Biol 27, R1177-R1192
DOI
|
33 |
Dyall SD, Brown MT and Johnson PJ (2004) Ancient Invasions: From endosymbionts to organelles. Science 304, 253-257
DOI
|
34 |
Anderson S, Bankier AT, Barrell BG et al (1981) Sequence and organization of the human mitochondrial genome. Nature 290, 457-465
DOI
|
35 |
Calkins MJ, Manczak M, Mao P, Shirendeb U and Reddy PH (2011) Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease. Hum Mol Genet 20, 4515-4529
DOI
|
36 |
Nemani N, Carvalho E, Tomar D et al (2018) MIRO-1 determines mitochondrial shape transition upon GPCR activation and Ca2+stress. Cell Rep 23, 1005-1019
DOI
|
37 |
Kang JS, Tian JH, Pan PY et al (2008) Docking of axonal Mitochondria by syntaphilin controls their mobility and affects short-term facilitation. Cell 132, 137-148
DOI
|
38 |
Lightowlers RN, Rozanska A and Chrzanowska- Lightowlers ZM (2014) Mitochondrial protein synthesis: Figuring the fundamentals, complexities and complications, of mammalian mitochondrial translation. FEBS Lett 588, 2496-2503
DOI
|
39 |
Richter-Dennerlein R, Oeljeklaus S, Lorenzi I et al (2016) Mitochondrial protein synthesis adapts to influx of nuclear-encoded protein. Cell 167, 471-483 e10
DOI
|
40 |
Li Z, Okamoto KI, Hayashi Y and Sheng M (2004) The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses. Cell 119, 873-887
DOI
|
41 |
Lorenz C, Lesimple P, Bukowiecki R et al (2017) Human iPSC-derived neural progenitors are an effective drug discovery model for neurological mtDNA disorders. Cell Stem Cell 20, 659-674 e9
DOI
|
42 |
Zsurka G and Kunz WS (2015) Mitochondrial dysfunction and seizures: The neuronal energy crisis. Lancet Neurol 14, 956-966
DOI
|
43 |
Martin MA, Blazquez A, Gutierrez-Solana LG et al (2005) Leigh syndrome associated with mitochondrial complex I deficiency due to a novel mutation in the NDUFS1 gene. Arch Neurol 62, 659-661
DOI
|
44 |
DiMauro S, Tanji K and Schon EA (2012) The many clinical faces of cytochrome c oxidase deficiency. In: Kadenbach B, ed. mitochondrial oxidative phosphorylation: nuclear-encoded genes, enzyme regulation, and pathophysiology. New York, NY: Springer New York Cahpter 14, 341-357
|
45 |
Marin SE, Mesterman R, Robinson B, Rodenburg RJ, Smeitink J and Tarnopolsky MA (2013) Leigh syndrome associated with mitochondrial complex I deficiency due to novel mutations In NDUFV1 and NDUFS2. Gene 516, 162-167
DOI
|
46 |
Distelmaier F and Koopman WJH, van den Heuvel LP et al (2009) Mitochondrial complex I deficiency: from organelle dysfunction to clinical disease. Brain 132, 833-842
|
47 |
Saneto R and Ruhoy I (2014) The genetics of Leigh syndrome and its implications for clinical practice and risk management. Appl Clin Genet 7, 221-234
|
48 |
Larsson NG (2010) Somatic Mitochondrial DNA mutations in mammalian aging. Annu Rev Biochem 79, 683-706
DOI
|
49 |
Rampelt H and Pfanner N (2016) Coordination of two genomes by mitochondrial translational plasticity. Cell 167, 308-310
DOI
|
50 |
Haynes CM, Yang Y, Blais SP, Neubert TA and Ron D (2010) The Matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans. Mol Cell 37, 529-540
DOI
|
51 |
Fox TD (2012) Mitochondrial protein synthesis, import, and assembly. Genetics 192, 1203-1234
DOI
|
52 |
Dolezal P, Likic V, Tachezy J and Lithgow T (2006) Evolution of the molecular machines for protein import into mitochondria. Science 313, 314-318
|
53 |
Lee SY, Kang MG, Shin S et al (2017) Architecture mapping of the inner mitochondrial membrane proteome by chemical tools in live cells. J Am Chem Soc 139, 3651-3662
DOI
|
54 |
Wiedemann N and Pfanner N (2017) mitochondrial machineries for protein import and assembly. Annu Rev Biochem 86, 685-714
DOI
|
55 |
Rhee HW, Zou P, Udeshi ND et al (2013) Proteomic mapping of mitochondria in living cells via spatially restricted enzymatic tagging. Science 339, 1328-1331
DOI
|
56 |
Lee SY, Kang MG, Park JS, Lee G, Ting AY and Rhee HW (2016) APEX fingerprinting reveals the subcellular localization of proteins of interest. Cell Rep 15, 1837-1847
DOI
|
57 |
Han S, Udeshi ND, Deerinck TJ et al (2017) Proximity biotinylation as a method for mapping proteins associated with mtDNA in living cells. Cell Chem Biol 24, 404-414
DOI
|
58 |
Hung V, Zou P, Rhee HW et al (2014) Proteomic mapping of the human mitochondrial intermembrane space in live cells via ratiometric APEX tagging. Mol Cell 55, 332-341
DOI
|
59 |
Gibson JH, Slobedman B, KN H et al (2010) Downstream targets of methyl CpG binding protein 2 and their abnormal expression in the frontal cortex of the human Rett syndrome brain. BMC Neurosci 11, 53
DOI
|
60 |
Kriaucionis S, Paterson A, Curtis J, Guy J, MacLeod N and Bird A (2006) Gene Expression Analysis Exposes mitochondrial abnormalities in a mouse model of rett syndrome. Mol Cell Biol 26, 5033-5042
DOI
|
61 |
Pecorelli A, Leoni G, Cervellati F et al (2013) Genes related to mitochondrial functions, protein degradation, and chromatin folding are differentially expressed in lymphomonocytes of rett syndrome patients. Mediators Inflamm 2013, 137629
|
62 |
Su H, Fan W, Coskun PE et al (2011) Mitochondrial dysfunction in CA1 hippocampal neurons of the UBE3A deficient mouse model for Angelman syndrome. Neurosci Lett 487, 129-133
DOI
|
63 |
Su D, Cha YM and West AE (2012) Mutation of Mecp2 alters transcriptional regulation of select immediate-early genes. Epigenetics 7, 146-154
DOI
|
64 |
Chahrour M, Jung SY, Shaw C et al (2008) MeCP2, a key contributor to neurological disease, activates and represses transcription. Science 320, 1224-1229
DOI
|
65 |
Shulyakova N, Andreazza AC, Mills LR and Eubanks JH (2017) Mitochondrial dysfunction in the pathogenesis of rett syndrome: Implications for mitochondria-targeted therapies. Front Cell Neurosci 11, 58
|
66 |
Khemakhem AM, Frye RE, El-Ansary A, Al-Ayadhi L and Bacha A Ben (2017) Novel biomarkers of metabolic dysfunction is autism spectrum disorder: potential for biological diagnostic markers. Metab Brain Dis 32, 1983-1997
DOI
|
67 |
James SJ, Melnyk S, Fuchs G et al (2009) Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autism. Am J Clin Nutr 89, 425-430
DOI
|
68 |
Chan DC (2006) Mitochondrial fusion and fission in mammals. Annu Rev Cell Dev Biol 22, 79-99
DOI
|
69 |
Hung V, Lam SS, Udeshi ND et al (2017) Proteomic mapping of cytosol-facing outer mitochondrial and ER membranes in living human cells by proximity biotinylation. Elife 6, 1-38
|
70 |
Westermann B (2010) Mitochondrial fusion and fission in cell life and death. Nat Rev Mol Cell Biol 11, 872-884
DOI
|
71 |
Chen H and Chan DC (2005) Emerging functions of mammalian mitochondrial fusion and fission. Hum Mol Genet 14 Spec No. 2, R283-289
|
72 |
Ishihara N, Nomura M, Jofuku A et al (2009) Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice. Nat Cell Biol 11, 958-966
DOI
|
73 |
Chang DTW, Honick AS and Reynolds IJ (2006) Mitochondrial trafficking to synapses in cultured primary cortical neurons. J Neurosci 26, 7035-7045
DOI
|
74 |
Fransson A, Ruusala A and Aspenstrom P (2006) The atypical Rho GTPases Miro-1 and Miro-2 have essential roles in mitochondrial trafficking. Biochem Biophys Res Commun 344, 500-510
DOI
|
75 |
Calvo SE, Clauser KR and Mootha VK (2016) MitoCarta2.0: An updated inventory of mammalian mitochondrial proteins. Nucleic Acids Res 44, D1251-1257
DOI
|
76 |
Smith AC and Robinson AJ (2016) MitoMiner v3.1, an update on the mitochondrial proteomics database. Nucleic Acids Res 44, D1258-1261
DOI
|
77 |
Prokisch H and Ahting U (2007) MitoP2, an integrated database for mitochondrial proteins. Methods Mol Biol 372, 573-586
|
78 |
Cotter D, Guda P, Fahy E and Subramaniam S (2004) MitoProteome: mitochondrial protein sequence database and annotation system. Nucleic Acids Res 32, D463-467
DOI
|
79 |
Perry SW, Norman JP, Litzburg A and Gelbard HA (2004) Antioxidants are required during the early critical period, but not later, for neuronal survival. J Neurosci Res 78, 485-492
DOI
|
80 |
James SJ, Rose S, Melnyk S et al (2009) Cellular and mitochondrial glutathione redox imbalance in lymphoblastoid cells derived from children with autism. FASEB J 23, 2374-2383
DOI
|
81 |
Prabakaran S, Swatton JE, Ryan MM et al (2004) Mitochondrial dysfunction in schizophrenia: Evidence for compromised brain metabolism and oxidative stress. Mol Psychiatry 9, 684-697
DOI
|
82 |
Chugani DC, Sundram BS, Behen M, Lee ML and Moore GJ (1999) Evidence of altered energy metabolism in autistic children. Prog Neuro-Psychopharmacology Biol Psychiatry 23, 635-641
DOI
|
83 |
Brennand K, Savas JN, Kim Y et al (2015) Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia. Mol Psychiatry 20, 361-368
DOI
|
84 |
Maurer I, Zierz S and Moller H (2001) Evidence for a mitochondrial oxidative phosphorylation defect in brains from patients with schizophrenia. Schizophr Res 48, 125-136
DOI
|
85 |
Scaini G, Rezin GT, Carvalho AF, Streck EL, Berk M and Quevedo J (2016) Mitochondrial dysfunction in bipolar disorder: Evidence, pathophysiology and translational implications. Neurosci Biobehav Rev 68, 694-713
DOI
|
86 |
Mertens J, Wang QW, Kim Y et al (2015) Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder. Nature 527, 95-99
DOI
|
87 |
Malik AN and Czajka A (2013) Is mitochondrial DNA content a potential biomarker of mitochondrial dysfunction? Mitochondrion 13, 481-492
DOI
|
88 |
Li G, Fang L, Fernandez G and Pleasure SJ (2013) The ventral hippocampus is the embryonic origin for adult neural stem cells in the dentate gyrus. Neuron 78, 658-672
DOI
|
89 |
Stiles J and Jernigan TL (2010) The basics of brain development. Neuropsychol Rev 20, 327-348
DOI
|
90 |
Fuentealba LC, Rompani SB, Parraguez JI et al (2015) Embryonic origin of postnatal neural stem cells. Cell 161, 1644-1655
DOI
|
91 |
Sorrells SF, Paredes MF, Cebrian-Silla A et al (2018) Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults. Nature 555, 377-381
DOI
|
92 |
Boldrini M, Fulmore CA, Tartt AN et al (2018) Human hippocampal neurogenesis persists throughout aging. Cell Stem Cell 22, 589-599
DOI
|
93 |
Kempermann G, Gage FH, Aigner L et al (2018) Human adult neurogenesis: Evidence and remaining questions. Cell Stem Cell 23, 25-30
DOI
|
94 |
Beckervordersandforth R, Zhang C and Lie DC (2015) Transcription-factor-dependent control of adult hippocampal neurogenesis. Cold Spring Harb Perspect Biol 7, a018879
DOI
|
95 |
Martynoga B, Drechsel D, Guillemot F et al (2012) Molecular control of neurogenesis : A view from the mammalian cerebral cortex molecular control of neurogenesis : A view from the mammalian cerebral cortex. Cold Spring Harb Perspect Biol 4, a008359
|
96 |
Hirabayashi Y (2004) The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cells. Development 131, 2791-2801
DOI
|
97 |
Lie DC, Colamarino SA, Song HJ et al (2005) Wnt signalling regulates adult hippocampal neurogenesis. Nature 437, 1370-1375
DOI
|
98 |
Budnik LT, Kloth S, Baur X, Preisser AM and Schwarzenbach H (2013) Circulating mitochondrial DNA as biomarker linking environmental chemical exposure to early preclinical lesions elevation of mtDNA in human serum after exposure to carcinogenic halo-alkane-based pesticides. Hoque MO, ed. PLoS One 8, e64413
DOI
|