1 |
Higdon JV and Frei B (2006) Coffee and health: a review of recent human research. Crit Rev Food Sci Nutr 46, 101-123
DOI
|
2 |
Kim AR, Yoon BK, Park H et al (2016) Caffeine inhibits adipogenesis through modulation of mitotic clonal expansion and the AKT/GSK3 pathway in 3T3-L1 adipocytes. BMB Rep 49, 111-115
DOI
|
3 |
Gross G, Jaccaud E and Huggett AC (1997) Analysis of the content of the diterpenes cafestol and kahweol in coffee brews. Food Chem Toxicol 35, 547-554
DOI
|
4 |
Rustan AC, Halvorsen B, Huggett AC, Ranheim T and Drevon CA (1997) Effect of coffee lipids (cafestol and kahweol) on regulation of cholesterol metabolism in HepG2 cells. Arterioscler Thromb Vasc Biol 17, 2140-2149
DOI
|
5 |
Park GH, Song HM and Jeong JB (2016) The coffee diterpene kahweol suppresses the cell proliferation by inducing cyclin D1 proteasomal degradation via ERK1/2, JNK and GKS3beta-dependent threonine-286 phosphorylation in human colorectal cancer cells. Food Chem Toxicol 95, 142-148
DOI
|
6 |
Choi DW, Lim MS, Lee JW et al (2015) The Cytotoxicity of Kahweol in HT-29 Human Colorectal Cancer Cells Is Mediated by Apoptosis and Suppression of Heat Shock Protein 70 Expression. Biomol Ther (Seoul) 23, 128-133
DOI
|
7 |
Kim J, Yang G, Kim Y, Kim J and Ha J (2016) AMPK activators: mechanisms of action and physiological activities. Exp Mol Med 48, e224
DOI
|
8 |
Stoppani J, Hildebrandt AL, Sakamoto K, Cameron-Smith D, Goodyear LJ and Neufer PD (2002) AMP-activated protein kinase activates transcription of the UCP3 and HKII genes in rat skeletal muscle. Am J Physiol Endocrinol Metab 283, E1239-E1248
DOI
|
9 |
Habinowski SA and Witters LA (2001) The effects of AICAR on adipocyte differentiation of 3T3-L1 cells. Biochem Biophys Res Commun 286, 852-856
DOI
|
10 |
Figarola JL and Rahbar S (2013) Smallmolecule COH-SR4 inhibits adipocyte differentiation via AMPK activation. Int J Mol Med 31, 1166-1176
DOI
|
11 |
McGee SL, van Denderen BJ, Howlett KF et al (2008) AMP-activated protein kinase regulates GLUT4 transcription by phosphorylating histone deacetylase 5. Diabetes 57, 860-867
DOI
|
12 |
Kim HG, Hwang YP and Jeong HG (2009) Kahweol blocks STAT3 phosphorylation and induces apoptosis in human lung adenocarcinoma A549 cells. Toxicol Lett 187, 28-34
DOI
|
13 |
Moeenfard M, Cortez A, Machado V et al (2016) Anti-Angiogenic Properties of Cafestol and Kahweol Palmitate Diterpene Esters. J Cell Biochem 117, 2748-2756
DOI
|
14 |
Liu XL, Ming YN, Zhang JY, Chen XY, Zeng MD and Mao YM (2017) Gene-metabolite network analysis in different nonalcoholic fatty liver disease phenotypes. Exp Mol Med 49, e283
DOI
|
15 |
Bray GA (2013) Why do we need drugs to treat the patient with obesity? Obesity (Silver Spring) 21, 893-899
DOI
|
16 |
Li Z, Maglione M, Tu W et al (2005) Meta-analysis: pharmacologic treatment of obesity. Ann Intern Med 142, 532-546
DOI
|
17 |
Xia Y, Kelton CM, Guo JJ, Bian B and Heaton PC (2015) Treatment of obesity: Pharmacotherapy trends in the United States from 1999 to 2010. Obesity (Silver Spring) 23, 1721-1728
DOI
|
18 |
Apovian CM, Aronne LJ, Bessesen DH et al (2015) Pharmacological management of obesity: an endocrine Society clinical practice guideline. J Clin Endocrinol Metab 100, 342-362
DOI
|
19 |
Hardie DG (2008) AMPK: a key regulator of energy balance in the single cell and the whole organism. Int J Obes (Lond) 32, Suppl 4: S7-12
DOI
|
20 |
Davies SP, Helps NR, Cohen PT and Hardie DG (1995) 5'-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase. Studies using bacterially expressed human protein phosphatase-2C alpha and native bovine protein phosphatase- 2AC. FEBS Lett 377, 421-425
DOI
|
21 |
Herrero-Martin G, Hoyer-Hansen M, Garcia-Garcia C et al (2009) TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells. EMBO J 28, 677-685
DOI
|
22 |
Goldstein DJ (1992) Beneficial health effects of modest weight loss. Int J Obes Relat Metab Disord 16, 397-415
|
23 |
Cheung BM, Cheung TT and Samaranayake NR (2013) Safety of antiobesity drugs. Ther Adv Drug Saf 4, 171-181
DOI
|
24 |
Khera R, Murad MH, Chandar AK et al (2016) Association of Pharmacological Treatments for Obesity With Weight Loss and Adverse Events: A Systematic Review and Meta-analysis. JAMA 315, 2424-2434
DOI
|
25 |
Yanovski SZ and Yanovski JA (2014) Long-term drug treatment for obesity: a systematic and clinical review. JAMA 311, 74-86
DOI
|
26 |
Choi HY, Saha SK, Kim K et al (2015) G protein-coupled receptors in stem cell maintenance and somatic reprogramming to pluripotent or cancer stem cells. BMB Rep 48, 68-80
DOI
|
27 |
Kang H and Hata A (2015) The role of microRNAs in cell fate determination of mesenchymal stem cells: balancing adipogenesis and osteogenesis. BMB Rep 48, 319-323
DOI
|
28 |
Fumimoto R, Sakai E, Yamaguchi Y et al (2012) The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci 118, 479-486
DOI
|
29 |
Cardenas C, Quesada AR and Medina MA (2011) Medina, Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One 6, e23407
DOI
|
30 |
Jeon SM (2016) Regulation and function of AMPK in physiology and diseases. Exp Mol Med 48, e245
DOI
|
31 |
Oh JH, Lee JT, Yang ES et al (2009) The coffee diterpene kahweol induces apoptosis in human leukemia U937 cells through down-regulation of Akt phosphorylation and activation of JNK. Apoptosis 14, 1378-1386
DOI
|
32 |
Morisco F, Lembo V, Mazzone G, Camera S and Caporaso N (2014) Coffee and liver health. J Clin Gastroenterol 48 Suppl 1, S87-90
|
33 |
Rosen ED and MacDougald OA (2006) MacDougald, Adipocyte differentiation from the inside out. Nat Rev Mol Cell Biol 7, 885-896
DOI
|
34 |
Zhang BB, Zhou G and Li C (2009) AMPK: an emerging drug target for diabetes and the metabolic syndrome. Cell Metab 9, 407-416
DOI
|