Adrenergic receptor β2 activation by stress promotes breast cancer progression through macrophages M2 polarization in tumor microenvironment |
Qin, Jun-fang
(School of Medicine, Nankai University)
Jin, Feng-jiao (School of Medicine, Nankai University) Li, Ning (School of Medicine, Nankai University) Guan, Hai-tao (School of Medicine, Nankai University) Lan, Lan (Tianjin Cancer Hospital, Tianjin Medical University) Ni, Hong (School of Medicine, Nankai University) Wang, Yue (School of Medicine, Nankai University) |
1 | Moreno-Smith M, Lutgendorf SK and Sood AK (2010) Impact of stress on cancer metastasis. Future Oncol 6, 1863-1881 DOI ScienceOn |
2 | McGregor BA and Antoni MH (2009) Psychological intervention and health outcomes among women treated for breast cancer: a review of stress pathways and biological mediators. Brain Behav Immun 23, 159-166 DOI ScienceOn |
3 | Schmidt C and Kraft K (1996) Beta-endorphin and catecholamine concentrations during chronic and acute stress in intensive care patients. Eur J Med Res 1, 528-532 |
4 | Deng GH, Liu J, Zhang J et al (2014) Exogenous norepinephrine attenuates the efficacy of sunitinib in a mouse cancer model. J Exp Clin Cancer Res 33, 21 DOI ScienceOn |
5 | Schuller HM and Al-Wadei HA (2010) Neurotransmitter receptors as central regulators of pancreatic cancer. Future Oncol 6, 221-228 DOI ScienceOn |
6 | Shang ZJ, Liu K and Liang de F (2009) Expression of beta2-adrenergic receptor in oral squamous cell carcinoma. J Oral Pathol Med 38, 371-376 DOI ScienceOn |
7 | Lee JW, Shahzad MM, Lin YG et al (2009) Surgical stress promotes tumor growth in ovarian carcinoma. Clin Cancer Res 15, 2695-2702 DOI ScienceOn |
8 | Perez Pinero C, Bruzzone A, Sarappa MG, Castillo LF and Luthy IA (2012) Involvement of alpha2- and beta2-adrenoceptors on breast cancer cell proliferation and tumour growth regulation. Br J Pharmacol 166, 721-736 DOI ScienceOn |
9 | Madden KS, Szpunar MJ and Brown EB (2011) beta-Adrenergic receptors (beta-AR) regulate VEGF and IL-6 production by divergent pathways in high beta-AR-expressing breast cancer cell lines. Breast Cancer Res Treat 130, 747-758 DOI |
10 | Vazquez SM, Pignataro O and Luthy IA (1999) Alpha2-adrenergic effect on human breast cancer MCF-7 cells. Breast Cancer Res Treat 55, 41-49 DOI ScienceOn |
11 | Bruzzone A, Pinero CP, Rojas P et al (2011) alpha(2)-Adrenoceptors enhance cell proliferation and mammary tumor growth acting through both the stroma and the tumor cells. Curr Cancer Drug Targets 11, 763-774 DOI ScienceOn |
12 | Khan S and Tisdale MJ (1999) Catabolism of adipose tissue by a tumour-produced lipid-mobilising factor. Int J Cancer 80, 444-447 DOI |
13 | Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A and Locati M (2004) The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol 25, 677-686 DOI ScienceOn |
14 | Ben-Eliyahu S, Page GG and Schleifer SJ (2007) Stress, NK cells, and cancer: Still a promissory note. Brain Behav Immun 21, 881-887 DOI ScienceOn |
15 | Pekarova M, Kralova J, Kubala L et al (2009) Carvedilol and adrenergic agonists suppress the lipopolysaccharideinduced NO production in RAW 264.7 macrophages via the adrenergic receptors. J Physiol Pharmacol 60, 143-150 |
16 | Mantovani A, Sozzani S, Locati M, Allavena P and Sica A (2002) Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 23, 549-555 DOI ScienceOn |
17 | Bingle L, Brown NJ and Lewis CE (2002) The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies. J Pathol 196, 254-265 DOI ScienceOn |
18 | Luo Y, Zhou H, Krueger J et al (2006) Targeting tumorassociated macrophages as a novel strategy against breast cancer. J Clin Invest 116, 2132-2141 DOI ScienceOn |
19 | Du Y, Yan L, Du H et al (2012) beta1-adrenergic receptor autoantibodies from heart failure patients enhanced TNF-alpha secretion in RAW264.7 macrophages in a largely PKA-dependent fashion. J Cell Biochem 113, 3218-3228 DOI ScienceOn |
20 | Huang JL, Zhang YL, Wang CC et al (2012) Enhanced phosphorylation of MAPKs by NE promotes TNF-alpha production by macrophage through alpha adrenergic receptor. Inflammation 35, 527-534 DOI ScienceOn |
21 | Wang Q, Ni H, Lan L, Wei X, Xiang R and Wang Y (2010) Fra-1 protooncogene regulates IL-6 expression in macrophages and promotes the generation of M2d macrophages. Cell Res 20, 701-712 DOI ScienceOn |
22 | Yang Y, Qin J, Lan L et al (2014) M-CSF cooperating with NFkappaB induces macrophage transformation from M1 to M2 by upregulating c-Jun. Cancer Biol Ther 15, 99-107 DOI ScienceOn |
23 | Obeid EI and Conzen SD (2013) The role of adrenergic signaling in breast cancer biology. Cancer Biomark 13, 161-169 DOI |
24 | Grailer JJ, Haggadone MD, Sarma JV, Zetoune FS and Ward PA (2014) Induction of M2 regulatory macrophages through the beta2-adrenergic receptor with protection during endotoxemia and acute lung injury. J Innate Immun 6, 607-618 DOI ScienceOn |
25 | Thaker PH, Han LY, Kamat AA et al (2006) Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma. Nat Med 12, 939-944 DOI ScienceOn |
26 | Lamkin DM, Sung HY, Yang GS et al (2015) alphaAdrenergic blockade mimics the enhancing effect of chronic stress on breast cancer progression. Psychoneuroendocrinology 51C, 262-270 DOI ScienceOn |
27 | Yang EV, Sood AK, Chen M et al (2006) Norepinephrine up-regulates the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumor cells. Cancer Res 66, 10357-10364 DOI ScienceOn |
28 | Martinez FO, Sica A, Mantovani A and Locati M (2008) Macrophage activation and polarization. Front Biosci 13, 453-461 DOI |
29 | Sigola LB and Zinyama RB (2000) Adrenaline inhibits macrophage nitric oxide production through beta1 and beta2 adrenergic receptors. Immunology 100, 359-363 DOI |
30 | Boomershine CS, Lafuse WP and Zwilling BS (1999) Beta2-adrenergic receptor stimulation inhibits nitric oxide generation by Mycobacterium avium infected macrophages. J Neuroimmunol 101, 68-75 DOI ScienceOn |
31 | Su F, Ouyang N, Zhu P et al (2005) Psychological stress induces chemoresistance in breast cancer by upregulating mdr1. Biochem Biophys Res Commun 329, 888-897 DOI ScienceOn |