1 |
Jain RK (2005) Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 307, 58-62
DOI
ScienceOn
|
2 |
Poliseno L, Tuccoli A, Mariani L et al (2006) MicroRNAs modulate the angiogenic properties of HUVECs. Blood 108, 3068-3071
DOI
ScienceOn
|
3 |
Xu Q, Liu LZ, Qian X et al (2012) MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis. Nucleic Acids Res 40, 761-774
DOI
|
4 |
Guo ST, Jiang CC, Wang GP et al (2013) MicroRNA-497 targets insulin-like growth factor 1 receptor and has a tumour suppressive role in human colorectal cancer. Oncogene 32, 1910-1920
DOI
ScienceOn
|
5 |
Sundaram P, Hultine S, Smith LM et al (2011) p53-responsive miR-194 inhibits thrombospondin-1 and promotes angiogenesis in colon cancers. Cancer Res 71, 7490-7501
DOI
|
6 |
Dews M, Homayouni A, Yu D et al (2006) Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster. Nat Genet 38, 1060-1065
DOI
ScienceOn
|
7 |
Kalluri R and Weinberg RA (2009) The basics of epithelial-mesenchymal transition. J Clin Invest 119, 1420-1428
DOI
ScienceOn
|
8 |
Thiery JP, Acloque H, Huang RY and Nieto MA (2009) Epithelial-mesenchymal transitions in development and disease. Cell 139, 871-890
DOI
ScienceOn
|
9 |
Burk U, Schubert J, Wellner U et al (2008) A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep 9, 582-589
DOI
ScienceOn
|
10 |
Gregory PA, Bracken CP, Smith E et al (2011) An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition. Mol Biol Cell 22, 1686-1698
DOI
|
11 |
Gregory PA, Bert AG, Paterson EL et al (2008) The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 10, 593-601
DOI
ScienceOn
|
12 |
Park SM, Gaur AB, Lengyel E and Peter ME (2008) The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev 22, 894-907
DOI
ScienceOn
|
13 |
Hur K, Toiyama Y, Takahashi M et al (2013) MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis. Gut 62, 1315-1326
DOI
ScienceOn
|
14 |
Rokavec M, Oner MG, Li H et al (2014) IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis. J Clin Invest 124, 1853-1867
DOI
ScienceOn
|
15 |
Booth RA (2007) Minimally invasive biomarkers for detection and staging of colorectal cancer. Cancer Lett 249, 87-96
DOI
ScienceOn
|
16 |
Habermann JK, Bader FG, Franke C et al (2008) From the genome to the proteome--biomarkers in colorectal cancer. Langenbecks Arch Surg 393, 93-104
DOI
|
17 |
Soreide K, Nedrebo BS, Knapp JC, Glomsaker TB, Soreide JA and Korner H (2009) Evolving molecular classification by genomic and proteomic biomarkers in colorectal cancer: potential implications for the surgical oncologist. Surg Oncol 18, 31-50
DOI
ScienceOn
|
18 |
Duffy MJ (2001) Carcinoembryonic antigen as a marker for colorectal cancer: is it clinically useful? Clin Chem 47, 624-630
|
19 |
Toiyama Y, Takahashi M, Hur K et al (2013) Serum miR-21 as a diagnostic and prognostic biomarker in colorectal cancer. J Natl Cancer Inst 105, 849-859
DOI
ScienceOn
|
20 |
Mandel JS, Bond JH, Church TR et al (1993) Reducing mortality from colorectal cancer by screening for fecal occult blood. Minnesota Colon Cancer Control Study. N Engl J Med 328, 1365-1371
DOI
ScienceOn
|
21 |
Kanaan Z, Roberts H, Eichenberger MR et al (2013) A plasma microRNA panel for detection of colorectal adenomas: a step toward more precise screening for colorectal cancer. Ann Surg 258, 400-408
DOI
ScienceOn
|
22 |
Wang S, Xiang J, Li Z et al (2015) A plasma microRNA panel for early detection of colorectal cancer. Int J Cancer 136, 152-161
DOI
ScienceOn
|
23 |
Toiyama Y, Hur K, Tanaka K et al (2014) Serum miR-200c is a novel prognostic and metastasis-predictive biomarker in patients with colorectal cancer. Ann Surg 259, 735-743
DOI
|
24 |
Hur K, Toiyama Y, Schetter AJ et al (2015) Identification of a Metastasis-Specific MicroRNA Signature in Human Colorectal Cancer. J Natl Cancer Inst 107
DOI
ScienceOn
|
25 |
Wang CJ, Stratmann J, Zhou ZG and Sun XF (2010) Suppression of microRNA-31 increases sensitivity to 5-FU at an early stage, and affects cell migration and invasion in HCT-116 colon cancer cells. BMC Cancer 10, 616
DOI
ScienceOn
|
26 |
Akao Y, Noguchi S, Iio A, Kojima K, Takagi T and Naoe T (2011) Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells. Cancer Lett 300, 197-204
DOI
ScienceOn
|
27 |
Nakagawa Y, Iinuma M, Naoe T, Nozawa Y and Akao Y (2007) Characterized mechanism of alpha-mangostin-induced cell death: caspase-independent apoptosis with release of endonuclease-G from mitochondria and increased miR-143 expression in human colorectal cancer DLD-1 cells. Bioorg Med Chem 15, 5620-5628
DOI
ScienceOn
|
28 |
Bartel DP (2009) MicroRNAs: target recognition and regulatory functions. Cell 136, 215-233
DOI
ScienceOn
|
29 |
Ng EK, Tsang WP, Ng SS et al (2009) MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer. Br J Cancer 101, 699-706
DOI
ScienceOn
|
30 |
Friedman JM and Jones PA (2009) MicroRNAs: critical mediators of differentiation, development and disease. Swiss Med Wkly 139, 466-472
|
31 |
Kim VN, Han J and Siomi MC (2009) Biogenesis of small RNAs in animals. Nat Rev Mol Cell Biol 10, 126-139
DOI
ScienceOn
|
32 |
Siegel R, Desantis C and Jemal A (2014) Colorectal cancer statistics, 2014. CA Cancer J Clin 64, 104-117
DOI
ScienceOn
|
33 |
Chang TC, Wentzel EA, Kent OA et al (2007) Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol Cell 26, 745-752
DOI
ScienceOn
|
34 |
Kopetz S, Chang GJ, Overman MJ et al (2009) Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy. J Clin Oncol 27, 3677-3683
DOI
ScienceOn
|
35 |
Rees M, Tekkis PP, Welsh FK, O'Rourke T and John TG (2008) Evaluation of long-term survival after hepatic resection for metastatic colorectal cancer: a multifactorial model of 929 patients. Ann Surg 247, 125-135
DOI
ScienceOn
|
36 |
Nagel R, le Sage C, Diosdado B et al (2008) Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer. Cancer Res 68, 5795-5802
DOI
ScienceOn
|
37 |
Diosdado B, van de Wiel MA, Terhaar Sive Droste JS et al (2009) MiR-17-92 cluster is associated with 13q gain and c-myc expression during colorectal adenoma to adenocarcinoma progression. Br J Cancer 101, 707-714
DOI
ScienceOn
|
38 |
Chen X, Guo X, Zhang H et al (2009) Role of miR-143 targeting KRAS in colorectal tumorigenesis. Oncogene 28, 1385-1392
DOI
ScienceOn
|
39 |
Guo C, Sah JF, Beard L, Willson JK, Markowitz SD and Guda K (2008) The noncoding RNA, miR-126, suppresses the growth of neoplastic cells by targeting phosphatidylinositol 3-kinase signaling and is frequently lost in colon cancers. Genes Chromosomes Cancer 47, 939-946
DOI
ScienceOn
|
40 |
Krichevsky AM and Gabriely G (2009) miR-21: a small multi-faceted RNA. J Cell Mol Med 13, 39-53
DOI
ScienceOn
|
41 |
Akao Y, Nakagawa Y and Naoe T (2006) let-7 microRNA functions as a potential growth suppressor in human colon cancer cells. Biol Pharm Bull 29, 903-906
DOI
ScienceOn
|
42 |
Asangani IA, Rasheed SA, Nikolova DA et al (2008) MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 27, 2128-2136
DOI
ScienceOn
|
43 |
Tsang WP and Kwok TT (2009) The miR-18a* microRNA functions as a potential tumor suppressor by targeting on K-Ras. Carcinogenesis 30, 953-959
DOI
ScienceOn
|
44 |
Hanahan D and Weinberg RA (2000) The hallmarks of cancer. Cell 100, 57-70
DOI
ScienceOn
|
45 |
Friedl P and Wolf K (2003) Tumour-cell invasion and migration: diversity and escape mechanisms. Nat Rev Cancer 3, 362-374
DOI
ScienceOn
|
46 |
Volinia S, Calin GA, Liu CG et al (2006) A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A 103, 2257-2261
DOI
ScienceOn
|
47 |
Sayed D, Rane S, Lypowy J et al (2008) MicroRNA-21 targets Sprouty2 and promotes cellular outgrowths. Mol Biol Cell 19, 3272-3282
DOI
ScienceOn
|
48 |
Zhu S, Si ML, Wu H and Mo YY (2007) MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1). J Biol Chem 282, 14328-14336
DOI
ScienceOn
|
49 |
Gabriely G, Wurdinger T, Kesari S et al (2008) MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. Mol Cell Biol 28, 5369-5380
DOI
ScienceOn
|
50 |
Vicinus B, Rubie C, Faust SK et al (2012) miR-21 functionally interacts with the 3'UTR of chemokine CCL20 and down-regulates CCL20 expression in miR-21 transfected colorectal cancer cells. Cancer Lett 316, 105-112
DOI
ScienceOn
|
51 |
Wang P, Zou F, Zhang X et al (2009) microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells. Cancer Res 69, 8157-8165
DOI
ScienceOn
|
52 |
Cottonham CL, Kaneko S and Xu L (2010) miR-21 and miR-31 converge on TIAM1 to regulate migration and invasion of colon carcinoma cells. J Biol Chem 285, 35293-35302
DOI
ScienceOn
|
53 |
Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST and Patel T (2007) MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 133, 647-658
DOI
ScienceOn
|
54 |
Slaby O, Svoboda M, Fabian P et al (2007) Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancer. Oncology 72, 397-402
DOI
ScienceOn
|
55 |
Faltejskova P, Besse A, Sevcikova S et al (2012) Clinical correlations of miR-21 expression in colorectal cancer patients and effects of its inhibition on DLD1 colon cancer cells. Int J Colorectal Dis 27, 1401-1408
DOI
ScienceOn
|
56 |
Chen HY, Lin YM, Chung HC et al (2012) miR-103/107 promote metastasis of colorectal cancer by targeting the metastasis suppressors DAPK and KLF4. Cancer Res 72, 3631-3641
DOI
ScienceOn
|
57 |
Fu J, Tang W, Du P et al (2012) Identifying microRNAmRNA regulatory network in colorectal cancer by a combination of expression profile and bioinformatics analysis. BMC Syst Biol 6, 68
DOI
|
58 |
Harris TA, Yamakuchi M, Ferlito M, Mendell JT and Lowenstein CJ (2008) MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1. Proc Natl Acad Sci U S A 105, 1516-1521
DOI
ScienceOn
|
59 |
Huang Z, Huang D, Ni S, Peng Z, Sheng W and Du X (2010) Plasma microRNAs are promising novel biomarkers for early detection of colorectal cancer. Int J Cancer 127, 118-126
DOI
ScienceOn
|
60 |
Kanaan Z, Rai SN, Eichenberger MR et al (2012) Differential microRNA expression tracks neoplastic progression in inflammatory bowel disease-associated colorectal cancer. Hum Mutat 33, 551-560
DOI
ScienceOn
|
61 |
Vickers MM, Bar J, Gorn-Hondermann I et al (2012) Stagedependent differential expression of microRNAs in colorectal cancer: potential role as markers of metastatic disease. Clin Exp Metastasis 29, 123-132
DOI
ScienceOn
|
62 |
Lu LF and Liston A (2009) MicroRNA in the immune system, microRNA as an immune system. Immunology 127, 291-298
DOI
ScienceOn
|
63 |
Bu P, Chen KY, Chen JH et al (2013) A microRNA miR-34a-regulated bimodal switch targets Notch in colon cancer stem cells. Cell Stem Cell 12, 602-615
DOI
ScienceOn
|
64 |
Hwang WL, Jiang JK, Yang SH et al (2014) MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells. Nat Cell Biol 16, 268-280
DOI
ScienceOn
|
65 |
Bitarte N, Bandres E, Boni V et al (2011) MicroRNA-451 is involved in the self-renewal, tumorigenicity, and chemoresistance of colorectal cancer stem cells. Stem Cells 29, 1661-1671
DOI
ScienceOn
|
66 |
Fang Y, Gu X, Li Z, Xiang J and Chen Z (2013) miR-449b inhibits the proliferation of SW1116 colon cancer stem cells through downregulation of CCND1 and E2F3 expression. Oncol Rep 30, 399-406
DOI
|
67 |
Bonauer A, Carmona G, Iwasaki M et al (2009) Micro-RNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice. Science 324, 1710-1713
DOI
ScienceOn
|
68 |
Yamakuchi M, Lotterman CD, Bao C et al (2010) P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis. Proc Natl Acad Sci U S A 107, 6334-6339
DOI
ScienceOn
|
69 |
Heldin CH, Vanlandewijck M and Moustakas A (2012) Regulation of EMT by TGFbeta in cancer. FEBS Lett 586, 1959-1970
DOI
ScienceOn
|