PEP-1-HO-1 prevents MPTP-induced degeneration of dopaminergic neurons in a Parkinson's disease mouse model |
Youn, Jong Kyu
(Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University)
Kim, Dae Won (Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Kangnung-Wonju National University) Kim, Seung Tae (Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University) Park, Sung Yeon (Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University) Yeo, Eun Ji (Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University) Choi, Yeon Joo (Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University) Lee, Hae-Ran (Department of Pediatrics, Hallym University Medical Center) Kim, Duk-Soo (Department of Anatomy, College of Medicine, Soonchunhyang University) Cho, Sung-Woo (Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine) Han, Kyu Hyung (Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University) Park, Jinseu (Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University) Eum, Won Sik (Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University) Hwang, Hyun Sook (Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University) Choi, Soo Young (Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University) |
1 | Innamorato, N. G., Jazwa, A., Rojo, A. I., Garcia, C., Fernandez-Ruiz, J., Grochot-Przeczek, A., Stachurska, A., Jozkowicz, A., Dulak, J. and Cuadrado, A. (2010) Different susceptibility to the Parkinson's toxin MPTP in mice lacking the redox master regulator Nrf2 or its target gene heme oxygenase-1. PLoS One 5, e11838. DOI ScienceOn |
2 | Brouard, S., Otterbein, L. E., Anrather, J., Tobiasch, E., Bach, F. H., Choi, A. M. and Soares, M. P. (2000) Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis. J. Exp. Med. 192, 1015-1026. DOI ScienceOn |
3 | Baranano, D. E., Rao, M., Ferris, C. D. and Snyder, S. H. (2002) Biliverdin reductase: a major physiologic cytoprotectant. Proc. Natl. Acad. Sci. U.S.A. 99, 16093-16098. DOI ScienceOn |
4 | Oberle, S., Schwartz, P., Abate, A. and Schroder, H. (1999) The antioxidant defense protein ferritin is a novel and specific target for pentaerithrityl tetranitrate in endothelial cells. Biochem. Biophys. Res. Commun. 261, 28-34. DOI ScienceOn |
5 | Kwon, S. W., Sohn, E. J., Kim, D. W., Jeong, H. J., Kim, M. J., Ahn, E. H., Kim, Y. N., Dutta, S., Kim, D. S., Park, J., Eum, W. S., Hwang, H. S. and Choi, S. Y. (2011) Anti-inflammatory effect of transduced PEP-1-heme oxygenase- 1 in Raw 264.7 cells and a mouse edema model. Biochem. Biophys. Res. Commun. 411, 354-359. DOI ScienceOn |
6 | Wadia, J. S. and Dowdy, S. F. (2002) Protein transduction technology. Curr. Opin. Biotechnol. 13, 52-56. DOI ScienceOn |
7 | Ahn, E. H., Kim, D. W., Shin, M. J., Kim, Y. N., Kim, H. R., Woo, S. J., Kim, S. M., Kim, D. S., Kim, J., Park, J., Eum, W. S., Hwang, H. S. and Choi, S. Y. (2013) PEP-1-ribosomal protein S3 protects dopaminergic neurons in an MPTP-induced Parkinson's disease mouse model. Free Radic. Biol. Med. 55, 36-45. DOI ScienceOn |
8 | Lee, S. H., Kim, D. W., Eom, S. A., Jun, S. Y., Park, M., Kim, D. S., Kwon, H. J., Kwon, H. Y., Han, K. H., Park, J., Hwang, H. S., Eum, W. S. and Choi, S. Y. (2012) Suppression of 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced skin inflammation in mice by transduced Tat-Annexin protein. BMB Rep. 45, 354-359. DOI ScienceOn |
9 | Miller, R. L., James-Kracke, M., Sun, G. Y. and Sun, A. Y. (2009) Oxidative and inflammatory pathways in Parkinson's disease. Neurochem. Res. 34, 55-65. DOI ScienceOn |
10 | Schipper, H. M. (2004) Heme oxygenase expression in human central nervous system disorders. Free Radic. Biol. Med. 37, 1995-2011. DOI ScienceOn |
11 | Schipper, H. M. (2000) Heme oxygenase-1: role in brain aging and neurodegeneration. Exp. Gerontol. 35, 821-830. DOI ScienceOn |
12 | Tronel, C., Rochefort, G. Y., Arlicot, N., Bodard, S., Chalon, S. and Antier, D. (2013) Oxidative stress is related to the deleterious effects of heme oxygenase-1 in an in vivo neuroinflammatory rat model. Oxid. Med. Cell Longev. 2013, Article ID 264935. |
13 | Panahian, N., Yoshiura, M. and Maines, M. D. (1999) Overexpression of heme oxygenase-1 is neuroprotective in a model of permanent middle cerebral artery occlusion in transgenic mice. J. Neurochem. 72, 1187-1203. |
14 | Chen, K., Gunter, K. and Maines, M. D. (2000) Neurons overexpressing heme oxygenase-1 resist oxidative stress-mediated cell death. J. Neurochem. 75, 304-313. |
15 | Hung, S. Y., Liou, H. C., Kang, K. H., Wu, R. M., Wen, C. C. and Fu, W. M. (2008) Overexpression of heme oxygenase- 1 protects dopaminergic neurons against 1-methyl-4- phenylpyridinium-induced neurotoxicity. Mol. Pharmacol. 74, 1564-1575. DOI ScienceOn |
16 | Kim, D. S., Sohn, E. J., Kim, D. W., Kim, Y. N., Eom, S. A., Yoon, G. H., Cho, S. W., Lee, S. H., Hwang, H. S., Cho, Y. S., Park, J., Eum, W. S. and Choi, S. Y. (2012) PEP-1-p18 prevents neuronal cell death by inhibiting oxidative stress and Bax expression. BMB Rep. 45, 532-537. DOI ScienceOn |
17 | Chen-Roetling, J., Benvenisti-Zarom, L. and Regan, R. F. (2005) Cultured astrocytes from heme oxygenase-1 knockout mice are more vulnerable to heme-mediated oxidative injury. J. Neurosci. Res. 82, 802-810. DOI ScienceOn |
18 | Zeynalov, E., Shah, Z. A., Li, R. C. and Dore, S. (2009) Heme oxygenase 1 is associated with ischemic preconditioning- induced protection against brain ischemia. Neurobiol. Dis. 35, 264-269. DOI ScienceOn |
19 | Jeong, G. S., Lee, D. S., Kim, D. C., Jahng, Y., Son, J. K., Lee, S. H. and Kim, Y. C. (2011) Neuroprotective and anti- inflammatory effects of mollugin via up-regulation of heme oxygenase-1 in mouse hippocampal and microglial cells. Eur. J. Pharmacol. 654, 226-234. DOI ScienceOn |
20 | Ahn, E. H., Kim, D. W., Kang, H. W., Shin, M. J., Won, M. H., Kim, J., Kim, D. J., Kwon, O. S., Kang, T. C., Han, K. H., Park, J., Eum, W. S. and Choi, S. Y. (2010) Transduced PEP-1-ribosomal protein S3 (rpS3) ameliorates 12-O-tetradecanoylphorbol- 13-acetate-induced inflammation in mice. Toxicol. 276, 192-197. DOI ScienceOn |
21 | Blandini, F. and Armentero, M. T. (2012) Animal models of Parkinson's disease. FEBS J. 279, 1156-1166. DOI ScienceOn |
22 | Weinreb, O., Mandel, S., Youdim, M. B. and Amit, T. (2013) Targeting dysregulation of brain iron homeostasis in Parkinson's disease by iron chelators. Free Radic. Biol. Med. 62, 52-64. DOI ScienceOn |
23 | Morse, D. and Choi, A. M. (2002) Heme oxygenase-1: the "emerging molecule" has arrived. Am. J. Respir. Cell. Mol. Biol. 27, 8-16. DOI ScienceOn |
24 | Grochot-Przeczek, A., Dulak, J. and Jozkowicz, A. (2012) Haem oxygenase-1: non-canonical roles in physiology and pathology. Clin. Sci. (Lond). 122, 93-103. DOI |
25 | Morris, M. C., Depollier, J., Mery, J., Heitz, F. and Divita, G. (2001) A peptide carrier for the delivery of biologically active proteins into mammalian cells. Nat. Biotechnol. 19, 1173-1176. DOI ScienceOn |