Cooperative transcriptional activation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 genes by nuclear receptors including Liver-X-Receptor |
Back, Su Sun
(Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University)
Kim, Jinsu (Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University) Choi, Daehyung (Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University) Lee, Eui Sup (Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University) Choi, Soo Young (Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University) Han, Kyuhyung (Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University) |
1 | Sumi, K., Tanaka, T., Uchida, A., Magoori, K., Urashima, Y., Ohashi, R., Ohguchi, H., Okamura, M., Kudo, H., Daigo, K., Maejima, T., Kojima, N., Sakakibara, I., Jiang, S., Hasegawa, G., Kim, I., Osborne, T. F., Naito, M., Gonzalez, F. J., Hamakubo, T., Kodama, T. and Sakai, J. (2007) Cooperative interaction between hepatocyte nuclear factor 4 alpha and GATA transcription factors regulates ATP-binding cassette sterol transporters ABCG5 and ABCG8. Mol. Cell. Biol. 27, 4248-4260. DOI ScienceOn |
2 | Kim, J., Kim, H., Lee, Y., Yang, K., Byun, S. and Han, K. (2006) A simple and economical short-oligonucletotide- based approach to generate shRNA. J. Biochem. Mol. Biol. 39, 329-334. DOI ScienceOn |
3 | Robertson, A. G., Bilenky, M., Tam, A., Zhao, Y., Zeng, T., Thiessen, N., Cezard, T., Fejes, A. P., Wederell, E. D., Cullum, R., Euskirchen, G., Krzywinski, M., Birol, I., Snyder, M., Hoodless, P. A., Hirst, M., Marra, M. A. and Jones, S. J. M. (2008) Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding. Genome Res. 18, 1906-1917. DOI ScienceOn |
4 | Visel, A., Blow, M. J., Li, Z., Zhang, T., Akiyama, J. A., Holt, A., Plajzer-Frick, I., Shoukry, M., Wright, C., Chen, F., Afzal, V., Ren, B., Rubin, E. M. and Pennacchio, L. A. (2009) ChIP-seq accurately predicts tissue-specific activity of enhancers. Nature 457, 854-858. DOI ScienceOn |
5 | Cho, Y. S. , Han, D., Baek, G., Park, S. P., Yoon, S., Lim, W. K., Kim, C. R., Kim, H. D., Kang, H. S. and Han, K. (1996) Versatile luciferase reporter plasmids for transcription studies in diverse eukaryotic cells. Korean J. Zool. 39, 378-386. 과학기술학회마을 |
6 | Berge, K. E. , Tain, H., Graf, G. A., Yu, L., Grishin, N. V., Schultz, J., Kwiterovich, P., Shan, B., Barnes, R. and Hobbs, H. H. (2000) Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. Science 290, 1771-1775. DOI ScienceOn |
7 | Lee, M. H., Lu, K. and Patel, S. B. (2001) Genetic basis of sitosterolemia, Curr. Opin. Lipidol. 12, 141-149. DOI ScienceOn |
8 | Yu, L., Li-Hawkins, J., Hammer, R. E., Berge, K. E., Horton, J. D., Cohen, J. C. and Hobbs, H. H. (2002) Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol. J. Clin. Invest. 110, 671-680. DOI |
9 |
Dave, V. P. and Kaul, D. (2010) Coronary heart disease: Significance of liver X receptor |
10 | Lewis, G. F. and Rader, D. J. (2005) New insights into the regulation of HDL metabolism and reverse cholesterol transport. Circ. Res. 96, 1221-1232. DOI ScienceOn |
11 | Calpe-Berdiel, L., Rotllan, N., Fievet, C., Roig, R., Blanco-Vaca, F. and Escola-Gil, J. C. (2008) Liver X receptor-mediated activation of reverse cholesterol transport from macrophages to feces in vivo requires ABCG5/G8. J. Lipid Res. 49, 1904-1911. DOI ScienceOn |
12 | Van der Veen, J. N., Dijk, T. H., Vrins, C. L. J., van Meer, H., Havinga, R., Bijsterveld, K., Tietge, U. J. F., Groen, A. K. and Kuipers, F. (2009) Activation of the liver X receptor stimulates trans-intestinal excretion of plasma cholesterol. J. Biol. Chem. 284, 19211-19219. DOI ScienceOn |
13 | Remaley, A. T., Bark, S., Walts, A. D., Freeman, L., Shulenin, S., Annilo, T., Elgin, E., Rhodes, H. E., Joyce, C., Dean, M., Santamarina-Fojo, S. and Brewer, Jr. H. B. (2002) Comparative genome analysis of potential regulatory elements in the ABCG5-ABCG8 gene cluster. Biochem. Biophys. Res. Comm. 295, 276-282. DOI ScienceOn |
14 | Freeman, L. A., Kennedy, A., Wu, J., Bark, S., Remaley, A. T., Santamarina-Fojo, S. and Brewer, H. B. Jr. (2004) The orphan nuclear receptor LRH-1 activates the ABCG5/ABCG8 intergenic promoter. J. Lipid Res. 45, 1197-1206. DOI ScienceOn |
![]() |