Molecular mechanisms of luteolin-7-O-glucoside-induced growth inhibition on human liver cancer cells: G2/M cell cycle arrest and caspase-independent apoptotic signaling pathways |
Hwang, Yu-Jin
(Department of Agrofood Resources, National Academy of Agricultural Science, RDA)
Lee, Eun-Ju (Department of Agrofood Resources, National Academy of Agricultural Science, RDA) Kim, Haeng-Ran (Department of Agrofood Resources, National Academy of Agricultural Science, RDA) Hwang, Kyung-A (Department of Agrofood Resources, National Academy of Agricultural Science, RDA) |
1 | Chang, L. and Karin, M. (2001) Mammalian MAP kinase signaling cascades. Nature 410, 37-40. DOI ScienceOn |
2 | Luo, J. L., Kamata, H. and Karin, M. (2005) IKK/NF-kappa B signaling: balancing life and death - a new approach to cancer therapy. J. Clin. Invest. 115, 2625-2632. DOI ScienceOn |
3 | Wisdom, R., Johnson, R. S. and Moore, C. (1999) C-Jun regulates cell cycle progression and apoptosis by distinct mechanisms. EMBO J. 18, 188-197. DOI ScienceOn |
4 | Davis, R. J. (2000) Signal Transduction by the JNK Group of MAP Kinases. Cell 103, 239-252. DOI ScienceOn |
5 | Tong, C., Yin, Z., Song, Z., Dockendorff, A., Huang, C., Mariadason, J., Flavell, R. A., Davis, R. J., Augenlicht, L. H. and Yang, W. (2007) c-Jun NH2-Terminal kinase 1 plays a critical role in intestinal homeostasis and tumor suppression. Am. J. Pathol. 171, 297-303. DOI ScienceOn |
6 | Jee, H., Lee, S. H., Park, J. H., Lee, B. R. Nam, K. T. and Kim, D. Y. (2013) Connexin32 inhibits gastric carcinogenesis through cell cycle arrest and altered expression of and . BMB Rep. 46, 25-30. 과학기술학회마을 DOI ScienceOn |
7 | Curtin, J. F. and Cotter, T. G. (2003) Live and let die: regulatory mechanisms in Fas mediated apoptosis. Cell Signal. 15, 983-992. DOI ScienceOn |
8 | Lee, D. H., Rhee, J. G. and Lee, Y. J. (2009) Reactive oxygen species up-regulate p53 and Puma; a possible mechanism for apoptosis during combined treatment with TRAIL and wogonin. Br. J. Pharmacol. 157, 1189-1202. DOI ScienceOn |
9 | Lee, E. W., Seo, J. H., Jeong, M. H., Lee, S. S. and Song. J. H. (2012) The roles of FADD in extrinsic apoptosis and necroptosis. BMB Rep. 45, 496-508. 과학기술학회마을 DOI ScienceOn |
10 | Hengartner, M. O. (2000) The biochemistry of apoptosis. Nature 407, 770-776. DOI ScienceOn |
11 | Sauer, H., Wartenberg, M. and Hescheler, J. (2001) Reactive oxygen species as intracellular messengers during cell growth and differentiation. Cell Physiol. Biochem. 11, 173-186. DOI ScienceOn |
12 | Trivedi, P. P., Roberts, P. C., Wolf, N. A. and Swanborg, R. H. (2005) NK cells inhibit T cell proliferation via p21-mediated cell cycle arrest. J. Immunol. 174, 4590-4597. DOI |
13 | Okamoto, S., Kang, Y., Brechtel, C., Siviglia, E., Russo, R., Clemente, A., Harrop, A., McKercher, S., Kaul, M. and Lipton, S. (2007) HIV/gp120 decreases adult neural progenitor cell proliferation via checkpoint kinase-mediated cell-cycle withdrawal and G1 arrest. Cell Stem Cell. 1, 230-236. DOI ScienceOn |
14 | Liang, Q., Xiong, H., Zhao, Z., Jia, D., Li, W., Qin, H., Deng, J., Gao, L., Zhang, H. and Gao, G. (2009) Inhibition of transcription factor STAT5b suppresses proliferation, induces G1 cell cycle arrest and reduces tumor cell invasion in human glioblastoma multiforme cells. Cancer Lett. 273, 164-171. DOI ScienceOn |
15 | Evan, G. I. and Vousden, K. H. (2001) Proliferation, cell cycle and apoptosis in cancer. Nature 411, 342-348. DOI ScienceOn |
16 | Ko, W. G., Kang, T. H., Lee, S. J., Kim, Y. C. and Lee, B. H. (2000) Effects of luteolin on the inhibition of proliferation and induction of apoptosis in human myeloid leukaemia cells. Phytother. Res. 16, 295-298. |
17 | Choi, J. A., Kim, J. Y., Lee, J. Y., Kang, C. M., Kwon, H. J., Yoo, Y. D., Kim, T. W., Lee, Y. S. and Lee, S. J. (2001) Induction of cell cycle arrest and apoptosis in human breast cancer cells by quercetin. Int. J. Oncol. 19, 837-844. |
18 | Fimognari, C., Nusse, M., Cesari, R., Iori, R., Cantelli-Forti, G. and Hrelia, P. (2002) Growth inhibition, cell-cycle arrest and apoptosis in human T-cell leukemia by the isothiocyanate sulforaphane. Carcinogenesis 23, 581-586. DOI ScienceOn |
19 | Liou, S. F., Lin, H. H., Liang, J. C., Chen, I. J. and Yeh, J. L. (2009) Inhibition of human prostate cancer cells proliferation by a selective alpha1-adrenoceptor antagonist labedipinedilol-A involves cell cycle arrest and apoptosis. Toxicology 256, 13-24. DOI ScienceOn |
20 | Hwang, K. A., Hwang, Y. J., Park, D. S., Kim, J.-H. and Om, A. S. (2011) In vitro investigation of antioxidant and anti-apoptotic activities of Korean wild edible vegetable extracts and their correlation with apoptotic gene expression in HepG2 cells. Food Chem. 125, 483-487. DOI ScienceOn |
21 | Lee, S. H., Lee, E. and Ko, Y. T. (2012) Anti-inflammatory effects of a methanol extract from Pulsatilla koreana in lipopolysaccharide-exposed rats. BMB Rep. 45, 371-376. 과학기술학회마을 DOI ScienceOn |
22 | Kishore, K. C., Arifullah, M., Gayathri, D., Ramagopal, G. and Sathees, C. R. (2007) Phytochemical antimicrobial studies of methy angolensate and luteolin-7-O-glucoside isolated from callus cultures of Soymida febrifuga. Int. J. Biomed. Sci. 3, 269-278. |
23 | Zeuner, A., Eramo, A., Testa, U., Felli, N., Pelosi, E., Mariani, G., Srinivasula, S. M., Alnemri, E. S., Condorelli, G., Peschle, C. and De Maria, R. (2003) Control of erythroid cell production via caspase-mediated cleavage of transcription factor SCL/Tal-1. Cell Death Differ. 10, 905-913. DOI ScienceOn |
24 | Cakir, A., Mavi, A., Kazaz, C., Yildirim, A. and Kufrevioglu, O. I. (2006) Antioxidant activities of the extracts and components of Teucrium orientale L. var. orientale. Turk. J. Chem. 30, 483-494. |
25 | Chung, H. and David, D. K. (2004) Luteolin-7-O-glucoside from dandelion flower suppress iNOS and COX-2 in RAW 264.7 cells. Mol. Cell Biochem. 265, 107-113. DOI ScienceOn |
26 | Kitanaka, C., Kato, K. and Tanaka, Y. (2007) Ras protein expression and autophagic tumor cell death in neuroblastoma. Am. J. Surg. Pathol. 31, 153-155. DOI ScienceOn |
27 | LeBel, C. P., Ischiropoulos, H. and Bondy, S. C. (1992) Evaluation of the probe 2', 7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress. Chem. Res. Toxicol. 5, 227-231. DOI ScienceOn |
28 | Guay, J., Lambert, H., Gingras, G., Lavoie, J. N., Huot, J. and Landry, J. (1997) Regulation of actinfilament dynamics by p38 map kinase-mediated phosphorylation of heat shockprotein. J. Cell Sci. 110, 357-368. |
29 | Hedges, J. C., Dechert, M. A., Yamboliev, I. A., Martin, J. L., Hickey, E., Weber, L. A. and Gerthoffer, W. T. (1999) A role for p38(MAPK)/HSP27 pathway in smooth muscle cell migration. J. Biol. Chem. 274, 24211-24219. DOI |
30 | Chan, K. T., Li, K., Liu, S. L., Chu, K. H., Toh, M. and Xie, W. D. (2010) Cucurbitacin B inhibits STAT3 and the Raf/MEK/ERK pathway in leukemia cell line K562. Cancer Lett. 289, 46-52. DOI ScienceOn |
31 | Fracasso, M. E., Perbellini, L., Solda, S., Talamini, G. and Franceschetti, P. (2002) Lead induced DNA strand breaks in lymphocytes of exposed workers: role of reactive oxygen species and protein kinase C. Mutat. Res. 515, 159-169. DOI ScienceOn |
32 | Rana, S., Gupta, K., Gomez, J., Matsuyama, S., Chakrabarti, A., Agarwal, M. L., Agarwal, A., Agarwal, M. K. and Wald, D. N. (2010) Securinine induces p73-dependent apoptosis preferentially in p53-deficient colon cancer cells. FASEB J. 24, 2126-2134. DOI ScienceOn |
33 | Wang, Y., Ma, X. Q., Yan, S. S., Shen, S. S., Zhu, H. L., Gu, Y., Wang, H. B., Qin, G. W. and Yu, Q. (2009) 17-Hydroxy-jolkinolide B inhibits signal transducers and activators of transcription 3 signaling by covalently cross-linking Janus kinases and induces apoptosis of human cancer cells. Cancer Res. 69, 7302-7310. DOI ScienceOn |
34 | Cohen, G. M. (1997) Caspases: the executioners of apoptosis. J. Biochem. 326, 1-6. |
35 | Megan, C., Alice, G. and Patricia, W. (2010) A role for p38 stress-activated protein kinase inregulation of cell growth via TORC1. Mol. Cell. Biol. 30, 481-495. DOI ScienceOn |
36 | Mansouri, A., Ridgway, L. D., Korapati, A. L., Zhang, Q. X., Tian, L., Wang, Y. B., Siddik, Z. H., Mills, G. B. and Claret, F. X. (2003) Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells. J. Biol. Chem. 278, 19245-19256. DOI ScienceOn |
37 | Bulavin, D., Kovalsky, O., Hollander, M. C. and Fornace, A. (2003) Loss of oncogenic H-ras-induced cell cycle arrest and p38 mitogen-activated protein kinase activation by disruption of GADD45a. Mol. Cell. Biol. 23, 3859-3871. DOI |
38 | Chandra, J., Samali, A. and Orrenius, S. (2000) Triggering and modulation of apoptosis by oxidative stress. Free Radic. Biol. Med. 29, 323-333. DOI ScienceOn |