Downregulation of Foxe1 by HR suppresses Msx1 expression in the hair follicles of HrHp mice |
Choi, Jee-Hyun
(Department of Biomedical Sciences, Research Institute of Molecular Genetics, College of Medicine, The Catholic University of Korea)
Kim, Byong-Kyu (Department of Biomedical Sciences, Research Institute of Molecular Genetics, College of Medicine, The Catholic University of Korea) Kim, Jeong-Ki (Department of Biomedical Sciences, Research Institute of Molecular Genetics, College of Medicine, The Catholic University of Korea) Lee, Hwa-Young (Department of Biomedical Sciences, Research Institute of Molecular Genetics, College of Medicine, The Catholic University of Korea) Park, Jong-Keun (Department of Biomedical Sciences, Research Institute of Molecular Genetics, College of Medicine, The Catholic University of Korea) KimYoon, Sung-Joo (Department of Biomedical Sciences, Research Institute of Molecular Genetics, College of Medicine, The Catholic University of Korea) |
1 | Reddy, S., Andl, T., Bagasra, A., Lu, M. M., Epstein, D. J., Morrisey, E. E. and Millar, S. E. (2001) Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis. Mech. Dev. 107, 69-82. DOI ScienceOn |
2 | Iseki, S., Araga, A., Ohuchi, H., Nohno, T., Yoshioka, H., Hayashi, F. and Noji, S. (1996) Sonic hedgehog is expressed in epithelial cells during development of whisker, hair, and tooth. Biochem. Biophys. Res. Commun. 218, 688-693. DOI ScienceOn |
3 | Chiang, C., Swan, R. Z., Grachtchouk, M., Bolinger, M., Litingtung, Y., Robertson, E. K., Cooper, M. K., Gaffield, W., Westphal, H., Beachy, P. A. and Dlugosz, A. A. (1999) Essential role for Sonic hedgehog during hair follicle morphogenesis. Dev. Biol. 205, 1-9. DOI ScienceOn |
4 | Livak, K. J. and Schmittgen, T. D. (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25, 402-408. DOI ScienceOn |
5 | Nam, Y., Kim, J. K., Cha, D. S., Cho, J. W., Cho, K. H., Yoon, S., Yoon, J. B., Oh, Y. S., Suh, J. G., Han, S. S., Song, C. W. and Yoon, S. K. (2006) A novel missense mutation in the mouse hairless gene causes irreversible hair loss: genetic and molecular analyses of Hr m1Enu. Genomics 87, 520-526. DOI ScienceOn |
6 | Flagg, A. E., Earley, J. U. and Svensson, E. C. (2007) FOG-2 attenuates endothelial-to-mesenchymal transformation in the endocardial cushions of the developing heart. Dev. Biol. 304, 308-316. DOI ScienceOn |
7 | Eichberger, T., Regl, G., Ikram, M. S., Neill, G. W., Philpott, M. P., Aberger, F. and Frischauf, A. M. (2004) FOXE1, a new transcriptional target of GLI2 is expressed in human epidermis and basal cell carcinoma. J. Invest. Dermatol. 122, 1180-1187. DOI ScienceOn |
8 | Brancaccio, A. (2004) Requirement of the forkhead gene Foxe1, a target of sonic hedgehog signaling, in hair follicle morphogenesis. Hum. Mol. Genet. 13, 2595- 2606. DOI ScienceOn |
9 | Venza, I., Visalli, M., Parrillo, L., De Felice, M., Teti, D. and Venza, M. (2010) Msx1 and TGF-3 are novel target genes functionally regulated by FOXE1. Hum. Mol. Genet. 20, 1016-1025. |
10 | Rendl, M., Lewis, L. and Fuchs, E. (2005) Molecular dissection of mesenchymal-epithelial interactions in the hair follicle. PLoS Biol. 3, e331. DOI ScienceOn |
11 | Revet, I., Huizenga, G., Koster, J., Volckmann, R., van Sluis, P., Versteeg, R. and Geerts, D. (2010) Msx1 induces the Wnt pathway antagonist genes DKK1, DKK2, DKK3, and SFRP1 in neuroblastoma cells, but does not block Wnt3 and Wnt5A signalling to DVL3. Cancer Lett. 289, 195-207. DOI ScienceOn |
12 | Liu, F., Chu, E. Y., Watt, B., Zhang, Y., Gallant, N. M., Andl, T., Yang, S. H., Lu, M. M., Piccolo, S., Schmidt- Ullrich, R., Taketo, M. M., Morrisey, E. E., Atit, R., Dlugosz, A. A. and Millar, S. E. (2008) Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis. Dev. Biol. 313, 210-224. DOI ScienceOn |
13 | Iwatsuki, K., Liu, H. X., Gronder, A., Singer, M. A., Lane, T. F., Grosschedl, R., Mistretta, C. M. and Margolskee, R. F. (2007) Wnt signaling interacts with Shh to regulate taste papilla development. Proc. Natl. Acad. Sci. U. S. A. 104, 2253-2258. DOI ScienceOn |
14 | Li, C., Xiao, J., Hormi, K., Borok, Z. and Minoo, P. (2002) Wnt5a participates in distal lung morphogenesis. Dev. Biol. 248, 68-81. DOI ScienceOn |
15 | St-Jacques, B., Dassule, H. R., Karavanova, I., Botchkarev, V. A., Li, J., Danielian, P. S., McMahon, J. A., Lewis, P. M., Paus, R. and McMahon, A. P. (1998) Sonic hedgehog signaling is essential for hair development. Curr. Biol. 8, 1058-1068. DOI ScienceOn |
16 | Beaudoin, G. M., 3rd, Sisk, J. M., Coulombe, P. A. and Thompson, C. C. (2005) Hairless triggers reactivation of hair growth by promoting Wnt signaling. Proc. Natl. Acad. Sci. U. S. A. 102, 14653-14658. DOI ScienceOn |
17 | Hsieh, J. C., Slater, S. A., Whitfield, G. K., Dawson, J. L., Hsieh, G., Sheedy, C., Haussler, C. A. and Haussler, M. R. (2010) Analysis of hairless corepressor mutants to characterize molecular cooperation with the vitamin D receptor in promoting the mammalian hair cycle. J. Cell. Biochem. 110, 671-686. DOI ScienceOn |
18 | Kim, B. K., Baek, I. C., Lee, H. Y., Kim, J. K., Song, H. H. and Yoon, S. K. (2010) Gene expression profile of the skin in the 'hairpoor' (HrHp) mice by microarray analysis. BMC Genomics 11, 640. DOI ScienceOn |
19 | Moraitis, A. N., Giguere, V. and Thompson, C. C. (2002) Novel mechanism of nuclear receptor corepressor interaction dictated by activation function 2 helix determinants. Mol. Cell. Biol. 22, 6831-6841. DOI |
20 | Potter, G. B., Beaudoin, G. M., 3rd, DeRenzo, C. L., Zarach, J. M., Chen, S. H. and Thompson, C. C. (2001) The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor. Genes Dev. 15, 2687-2701. DOI ScienceOn |
21 | Carlsson, P. (2002) Forkhead transcription factors: key players in development and metabolism. Dev. Biol. 250, 1-23. DOI ScienceOn |
22 | Mecklenburg, L., Nakamura, M., Sundberg, J. P. and Paus, R. (2001) The nude mouse skin phenotype: the role of Foxn1 in hair follicle development and cycling. Exp. Mol. Pathol. 71, 171-178. DOI ScienceOn |
23 | Lee, D., Prowse, D. M. and Brissette, J. L. (1999) Association between mouse nude gene expression and the initiation of epithelial terminal differentiation. Dev. Biol. 208, 362-374. |
24 | Perrone, L. (2000) The thyroid transcription factor 2 (TTF-2) is a promoter-specific DNA-binding independent transcriptional repressor. Biochem. Biophys. Res. Commun. 275, 203-208. DOI ScienceOn |
25 | Schmidt-Ullrich, R. and Paus, R. (2005) Molecular principles of hair follicle induction and morphogenesis. Bioessays. 27, 247-261. DOI ScienceOn |
26 | Paus, R. and Foitzik, K. (2004) In search of the "hair cycle clock": a guided tour. Differentiation 72, 489-511. DOI ScienceOn |
27 | Stenn, K. S. and Paus, R. (2001) Controls of hair follicle cycling. Physiol. Rev. 81, 449-494. DOI |
28 | Millar, S. E. (2002) Molecular mechanisms regulating hair follicle development. J. Invest. Dermatol. 118, 216-225. DOI ScienceOn |
29 | Mikkola, M. L. (2007) Genetic basis of skin appendage development. Semin. Cell. Dev. Biol. 18, 225-236. DOI ScienceOn |
30 | Shimomura, Y. and Christiano, A. M. (2010) Biology and genetics of hair. Annu. Rev. Genomics Hum. Genet. 11, 109-132. DOI ScienceOn |
31 | Baek, I. C., Kim, J. K., Cho, K. H., Cha, D. S., Cho, J. W., Park, J. K., Song, C. W. and Yoon, S. K. (2009) A novel mutation in Hr causes abnormal hair follicle morphogenesis in hairpoor mouse, an animal model for Marie Unna Hereditary Hypotrichosis. Mamm. Genome 20, 350-358. DOI |
32 | Kim, J. K., Kim, E., Baek, I. C., Kim, B. K., Cho, A. R., Kim, T. Y., Song, C. W., Seong, J. K., Yoon, J. B., Stenn, K. S., Parimoo, S. and Yoon, S. K. (2010) Overexpression of Hr links excessive induction of Wnt signaling to Marie Unna hereditary hypotrichosis. Hum. Mol. Genet. 19, 445-453. DOI ScienceOn |