Tumor necrosis factor-α converting enzyme (TACE) increases RANKL expression in osteoblasts and serves as a potential biomarker of periodontitis |
Lee, Ji-Hyun
(Department of Biochemistry, School of Dentistry, Kyungpook National University)
Choi, Young-Jin (Department of Biochemistry, School of Dentistry, Kyungpook National University) Heo, Sun-Hee (Department of Biochemistry, School of Dentistry, Kyungpook National University) Lee, Jae-Mok (Department of Periodontology, School of Dentistry, Kyungpook National University) Cho, Je-Yoel (Department of Biochemistry, School of Dentistry, Kyungpook National University) |
1 | Lee, J. H., Kim, B. G., Ahn, J. M., Park, H. J., Park, S. K., Yoo, J. S., Yates, J. R., 3rd and Cho, J. Y. (2010) Role of PI3K on the regulation of BMP2-induced beta-Catenin activation in human bone marrow stem cells. Bone 46, 1522-1532. DOI ScienceOn |
2 | Lau, Y. S., Adamopoulos, I. E., Sabokbar, A., Giele, H., Gibbons, C. L. and Athanasou, N. A. (2007) Cellular and humoral mechanisms of osteoclast formation in Ewing's sarcoma. Br. J. Cancer 96, 1716-1722. DOI ScienceOn |
3 | Bostanci, N., Ilgenli, T., Emingil, G., Afacan, B., Han, B., Toz, H., Atilla, G., Hughes, F. J. and Belibasakis, G. N. (2007) Gingival crevicular fluid levels of RANKL and OPG in periodontal diseases: implications of their relative ratio. J. Clin. Periodontol. 34, 370-376. DOI ScienceOn |
4 | Pan, B., Farrugia, A. N., To, L. B., Findlay, D. M., Green, J., Lynch, K. and Zannettino, A. C. (2004) The nitrogen-containing bisphosphonate, zoledronic acid, influences RANKL expression in human osteoblast-like cells by activating TNF-alpha converting enzyme (TACE). J. Bone. Miner. Res. 19, 147-154. DOI ScienceOn |
5 | Belibasakis, G. N., Meier, A., Guggenheim, B. and Bostanci, N. (2011) Oral biofilm challenge regulates the RANKL-OPG system in periodontal ligament and dental pulp cells. Microb. Pathog. 50, 6-11. DOI ScienceOn |
6 | Bostanci, N., Reddi, D., Rangarajan, M., Curtis, M. A. and Belibasakis, G. N. (2009) Porphyromonas gingivalis stimulates TACE production by T cells. J. Oral Microbiol. 24, 146-151. DOI ScienceOn |
7 | Lum, L., Wong, B. R., Josien, R., Becherer, J. D., Erdjument-Bromage, H., Schlondorff, J., Tempst, P., Choi, Y. and Blobel, C. P. (1999) Evidence for a role of a tumor necrosis factor-alpha (TNF-alpha)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic cell survival. J. Biol. Chem. 274, 13613-13618. DOI ScienceOn |
8 | Brechter, A. B., Persson, E., Lundgren, I. and Lerner, U. H. (2008) Kinin B1 and B2 receptor expression in osteoblasts and fibroblasts is enhanced by interleukin-1 and tumour necrosis factor-alpha. Effects dependent on activation of NF-kappaB and MAP kinases. Bone 43, 72-83. DOI ScienceOn |
9 | Franchimont, N., Lambert, C., Huynen, P., Ribbens, C., Relic, B., Chariot, A., Bours, V., Piette, J., Merville, M. P. and Malaise, M. (2005) Interleukin-6 receptor shedding is enhanced by interleukin-1beta and tumor necrosis factor alpha and is partially mediated by tumor necrosis factor alpha-converting enzyme in osteoblast-like cells. Arthritis Rheum. 52, 84-93. DOI ScienceOn |
10 | Listgarten, M. A. (1986) Pathogenesis of periodontitis. J. Clin. Periodontol. 13, 418-430. DOI |
11 | Mezyk-Kopec, R., Bzowska, M., Potempa, J., Bzowska, M., Jura, N., Sroka, A., Black, R. A. and Bereta, J. (2005) Inactivation of membrane tumor necrosis factor alpha by gingipains from Porphyromonas gingivalis. Infect. Immun. 73, 1506-1514. DOI ScienceOn |
12 | Sorsa, T., Suomalainen, K. and Uitto, V. J. (1990) The role of gingival crevicular fluid and salivary interstitial collagenases in human periodontal diseases. Arch. Oral Biol. 35 (Suppl), S193-196. DOI ScienceOn |
13 | Primakoff, P. and Myles, D. G. (2000) The ADAM gene family: surface proteins with adhesion and protease activity. Trends Genet. 16, 83-87. DOI ScienceOn |
14 | Bostanci, N., Emingil, G., Afacan, B., Han, B., Ilgenli, T., Atilla, G., Hughes, F. J. and Belibasakis, G. N. (2008) Tumor necrosis factor-alpha-converting enzyme (TACE) levels in periodontal diseases. J. Dent. Res. 87, 273-277. DOI ScienceOn |
15 | Schoppet, M., Preissner, K. T. and Hofbauer, L. C. (2002) RANK ligand and osteoprotegerin: paracrine regulators of bone metabolism and vascular function. Arterioscler. Thromb. Vasc. Biol. 22, 549-553. DOI ScienceOn |
16 | Krajewski, A. C., Biessei, J., Kunze, M., Maersch, S., Perabo, L. and Noack, M. J. (2009) Influence of lipopolysaccharide and interleukin-6 on RANKL and OPG expression and release in human periodontal ligament cells. Apmis. 117, 746-754. DOI ScienceOn |