Ex12 helper phage improves the quality of a phage-displayed antibody library by ameliorating the adverse effect of clonal variations |
Choi, Hyo-Jung
(Department of Systems Immunology, College of Biomedical Science, Kangwon National University)
Song, Suk-Yoon (IG Therapy Co., Rm A202, Biomedical Science Building, Kangwon National University) Yoon, Jae-Bong (Department of Systems Immunology, College of Biomedical Science, Kangwon National University) Liu, Li-Kun (Department of Systems Immunology, College of Biomedical Science, Kangwon National University) Cho, Jae-Youl (Institute of Antibody Research, Kangwon National University) Cha, Sang-Hoon (Department of Systems Immunology, College of Biomedical Science, Kangwon National University) |
1 | O'Connell, D., Becerril, B., Roy-Burman, A., Daws, M. and Marks, J. D. (2002) Phage versus phagemid libraries for generation of human monoclonal antibodies. J. Mol. Biol. 321, 49-56. DOI ScienceOn |
2 | Knappik, A. and Plückthun, A. (1995) Engineered turns of a recombinant antibody improve its in vivo folding. Protein Eng. 8, 81-89. DOI |
3 | Cabilly, S. (1989) Growth at sub-optimal temperatures allows the production of functional, antigen-binding Fab fragments in Escherichia coli. Gene 85, 553-557. DOI ScienceOn |
4 | De Bruin, R., Spelt, K., Mol, J., Koes, R. and Quattrocchio, F. (1999) Selection of high-affinity phage antibodies from phage display libraries. Nat. Biotechnol. 17, 397-399. DOI ScienceOn |
5 | Kretzschmar, T., Zimmermann, C. and Geiser, M. (1995) Selection procedures for nonmatured phage antibodies: a quantitative comparison and optimization strategies. Analytical. Biochem. 224, 413-419. DOI ScienceOn |
6 | Mutuberria, R., Hoogenboom, H. R., VanderLinden, E., DeBruine, A. P. and Roovers, R. C. (1999) Model systems to study the parameters determining the success of phage antibody selection on complex antigens. J. Immunol. Methods 231, 65-81. DOI ScienceOn |
7 | Baek, H., Suk, K., Kim, Y. and Cha, S. (2002) An improved helper phage system for efficient isolation of specific antibody molecules in phage display. Nucleic Acids Res. 30(5), e18. DOI ScienceOn |
8 | Cha, S., Leung, P. S. C., Coppel, R. L., VandeWater, J., Ansari, A. A. and Gershwin, M. E. (1994) Heterogeneity of combinatorial human autoantibodies against PDC-E2 and biliary epithelial cells in patients with primary biliary cirrhosis. Hepatology 20, 574-583. DOI ScienceOn |
9 | McCafferty, J. (1996) Phage display: factors affecting panning efficiency; in Phage Display of Peptides and Proteins, A Laboratory Manual, pp. 261, Academic Press Inc., San Diego, USA. |
10 | Corisdeo, S. and Wang, B. (2004) Functional expression and display of an antibody Fab fragment in Escherichia coli: study of vector designs and culture conditions. Prot. Exp. Purif. 34, 270-279. DOI ScienceOn |
11 | Assazy, H. M. E. and Highsmith, W. E. (2002) Phage display technology: clinical applications and recent Innovations. Clin. Biochem. 35, 425-445. DOI ScienceOn |
12 | Yamanaka, H. I., Kirii, Y. and Ohmoto, H. (1995) An improved phage display antibody cloning system using newly designed PCR primers optimized for Pfu DNA polymerase. J. Biochem. (Tokyo) 117, 1218-1227. DOI |
13 | Krebber, A., Bornhauser, S., Burmester, J., Honegger, A., Willuda, J., Bosshard, H. R. and Pluckthun, A. (1997) Reliable cloning of functional antibody variable domains from hybridomas and spleen cell repertoires employing a reengineered phage display system. J. Immunol. Methods 201, 35-55. DOI ScienceOn |
14 | Sambrook, J., Fritsch, E. F. and Maniatis, T. (1989) Molecular Cloning. A laboratory Manual. 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, USA. |
15 | Cha, S., Leung, P. S. C., Gershwin, M. E., Fletcher, M. P. and Ansari, A. A. (1993) Combinatorial autoantibodies to dihydrolipoamide acetyltransferase, the major autoantigen of primary biliary cirrhosis. Proc. Natl. Acad. Sci. 90, 2527-2531. DOI |
16 | McCafferty, J. and Johnson, K. S. (1996) Construction and screening of antibody display libraries; in Phage Display of Peptides and Proteins. A Laboratory Manual. pp. 79, Academic Press Inc., San Diego, USA. |
17 | Ostermeier, M. and Benkovic, S. J. (2000) A two-phagemid system for the creation of non-phage displayed antibody libraries approaching one trillion members. J. Immunol. Meth. 237,175-186. DOI ScienceOn |
18 | Barbs, C. F. 3rd., Kang, A. S., Lerner, R. A. and Benkovic, S. J. (1991) Assembly of combinatorial antibody libraries on phage surfaces: the gene III site. Proc. Natl. Acad. Sci. 88, 7978-7982. DOI ScienceOn |
19 | Hoogenboom, H. R., Griffiths, A. D., Johnson, K. S., Chiswell, D. J., Hudson, P. and Winter, G. (1991) Multi- subunit proteins on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chains. Nucleic Acids Res. 19, 4133-4137. DOI ScienceOn |
20 | Clark, M. A., Hammond, F. R., Papaioannou, A., Hawkins, N. J. and Ward, R. L. (1997) Regulation and expression of human Fabs under the control of the Escherichia coli arabinose promoter, PBAD. Immunotechnol. 3, 217-226. DOI ScienceOn |
21 | Dziegiel, M., Nielsen, L. K., Andersen, P. S., Blancher, A., Dickmeiss, E. and Engberg, J. (1995) Phage display used for gene cloning of human recombinant antibody against the erythrocyte surface antigen, rhesus D. J. Immunol. Methods 182, 7-19. DOI ScienceOn |
22 | Marks, J. D. and Bradbury, A. (2004) Selection of human antibodies from phage display libraries. Methods Mol. Biol. 248, 161-176. |
23 | Hoogenboom, H. R. and Chames, P. (2000) Natural and designer binding sites made by phage display technology. Immunol. Today 21, 371-378. DOI ScienceOn |
24 | Oh, M., Joo, H., Hur, B., Jeong, Y. and Cha, S. (2007) Enhancing phage display of antibody fragments using gIII-amber suppression. Gene 386, 81-89. DOI ScienceOn |