Association of PTGER gene family polymorphisms with aspirin intolerant asthma in Korean asthmatics
![]() ![]() |
Park, Byung-Lae
(Department of Genetic Epidemiology, SNP Genetics, Inc.)
Park, Se-Min (Genome Research Center for Allergy and Respiratory Medicine, Soonchunhyang University Hospital) Park, Jong-Sook (Genome Research Center for Allergy and Respiratory Medicine, Soonchunhyang University Hospital) Uh, Soo-Taek (Genome Research Center for Allergy and Respiratory Medicine, Soonchunhyang University Hospital) Choi, Jae-Sung (Genome Research Center for Allergy and Respiratory Medicine, Soonchunhyang University Hospital) Kim, Yong-Hoon (Division of Internal Medicine, Chungbuk National University, College of Medicine) Kim, Mi-Kyeong (Department of Allergy, Chonnam National University Medical School and Research Institute of Medical Sciences) Choi, In-Seon S. (Division of Pulmonology and Allergy, Department of Internal Medicine, Chung-Ang University Yongsan Hospital) Choi, Byoung-Whui (Department of Internal Medicine and Institute of Allergy and Clinical Immunology, Seoul National University College of Medicine) Cho, Sang-Heon (Division of Allergy and Immunology, Institute of Allergy, Department of Internal Medicine, Yonsei University College of Medicine) Hong, Chein-Soo (Pulmonary, Allergy & Critical Care Medicine, Hallym University College of Medicine) Lee, Yong-Won (Pulmonary, Allergy & Critical Care Medicine, Hallym University College of Medicine) Lee, Jae-Young (Department of Life Science, Sogang University) Park, Choon-Sik (Genome Research Center for Allergy and Respiratory Medicine, Soonchunhyang University Hospital) Shin, Hyoung-Doo (Department of Genetic Epidemiology, SNP Genetics, Inc.) |
1 | Loewe, G., Slapke, J. and Kunath, H. (1985) Nasal polyposis, bronchial asthma and analgesic intolerance. Rhinology. 23, 19-26. |
2 | Cormican, L. J., Farooque, S., Altmann, D. R. and Lee, T. H. (2005) Improvements in an oral aspirin challenge protocol for the diagnosis of aspirin hypersensitivity. Clin. Exp. Allergy. 35, 717-722. DOI ScienceOn |
3 | Oliphant, A., Barker, D. L., Stuelpnagel, J. R. and Chee, M. S. (2002) BeadArray technology: enabling an accurate, cost-effective approach to high-throughput genotyping. Biotechniques 32, S56-61. |
4 | Livak, K. J. (1999) Allelic discrimination using fluorogenic probes and the 5' nuclease assay. Genet. Anal. 14, 143-149. DOI ScienceOn |
5 | Hedrick, P. W. (1987) Gametic disequilibrium measures: proceed with caution. Genetics. 117, 331-341. |
6 | Stephens, M., Smith, N. J. and Donnelly, P. (2001) A new statistical method for haplotype reconstruction from population data. Am. J. Hum. Genet. 68, 978-989. DOI ScienceOn |
7 | Kunikata, T., Yamane, H., Segi, E., Matsuoka, T., Sugimoto, Y., Tanaka, S., Tanaka, H., Nagai, H., Ichikawa, A. and Narumiya, S. (2005) Suppression of allergic inflammation by the prostaglandin E receptor subtype EP3. Nat. Immunol. 6, 524-531. DOI ScienceOn |
8 | Kim, S. H., Kim, Y. K., Park, H. W., Jee, Y. K., Kim, S. H., Bahn, J. W., Chang, Y. S., Kim, S. H., Ye, Y. M., Shin, E. S., Lee, J. E., Park, H. S. and Min, K. U. (2007) Association between polymorphisms in prostanoid receptor genes and aspirin-intolerant asthma. Pharmacogenet. Genomics. 17, 295-304. |
9 | Jinnai, N., Sakagami, T., Sekigawa, T., Kakihara, M., Nakajima, T., Yoshida, K., Goto, S., Hasegawa, T., Koshino, T., Hasegawa, Y., Inoue, H., Suzuki, N., Sano, Y. and Inoue, I. (2004) Polymorphisms in the prostaglandin E2 receptor subtype 2 gene confer susceptibility to aspirin-intolerant asthma: a candidate gene approach. Hum. Mol. Genet. 13, 3203-3217. DOI ScienceOn |
10 | Park, H. W., Shin, E. S., Lee, J. E., Kim, S. H., Kim, S. S., Chang, Y. S., Kim, Y. K., Min, K. U., Kim, Y. Y. and Cho, S. H. (2007) Association between genetic variations in prostaglandin E2 receptor subtype EP3 gene (Ptger3) and asthma in the Korean population. Clin. Exp. Allergy 37, 1609-1615. DOI ScienceOn |
11 | Stock, J. L., Shinjo, K., Burkhardt, J., Roach, M., Taniguchi, K., Ishikawa, T., Kim, H. S., Flannery, P. J., Coffman, T. M., McNeish, J. D. and Audoly, L. P. (2001) The prostaglandin E2 EP1 receptor mediates pain perception and regulates blood pressure. J. Clin. Invest. 107, 325-331. DOI ScienceOn |
12 | Conklin, D., Jonassen, I., Aasland, R. and Taylor, W. R. (2002) Association of nucleotide patterns with gene function classes: application to human 3' untranslated sequences. Bioinformatics 18, 182-189. DOI ScienceOn |
13 | Vane, J. R., Bakhle, Y. S. and Botting, R. M. (1998) Cyclooxygenases 1 and 2. Annu. Rev. Pharmacol. Toxicol. 38, 97-120. DOI ScienceOn |
14 | Kim, T. H., Chang, H. S., Park, S. M., Nam, B. Y., Park, J. S., Rhim, T., Park, H. S., Kim, M. K., Choi, I. S., Cho, S. H., Chung, I. Y., Park, B. L., Park, C. S. and Shin, H. D. (2008) Association of angiotensin I-converting enzyme gene polymorphisms with aspirin intolerance in asthmatics. Clin. Exp. Allergy. 38, 1727-1737. |
15 | Celik, G., Bavbek, S., Misirligil, Z. and Melli, M. (2001) Release of cysteinyl leukotrienes with aspirin stimulation and the effect of prostaglandin E(2) on this release from peripheral blood leucocytes in aspirin-induced asthmatic patients. Clin. Exp. Allergy 31, 1615-1622. DOI ScienceOn |
16 | Szczeklik, A., Sanak, M., Nizankowska-Mogilnicka, E. and Kielbasa, B. (2004) Aspirin intolerance and the cyclooxygenase-leukotriene pathways. Curr. Opin. Pulm. Med. 10, 51-56. DOI ScienceOn |
17 | Snijdewint, F. G., Kalinski, P., Wierenga, E. A., Bos, J. D. and Kapsenberg, M. L. (1993) Prostaglandin E2 differentially modulates cytokine secretion profiles of human T helper lymphocytes. J. Immunol. 150, 5321-5329. |
18 | Betz, M. and Fox, B. S. (1991) Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines. J. Immunol. 146, 108-113. |
19 | Coleman, R. A., Smith, W. L. and Narumiya, S. (1994) International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes. Pharmacol. Rev. 46, 205-229. |
20 | Negishi, M., Sugimoto, Y. and Ichikawa, A. (1995) Molecular mechanisms of diverse actions of prostanoid receptors. Biochim. Biophys. Acta. 1259, 109-119. DOI ScienceOn |
21 | Narumiya, S., Sugimoto, Y. and Ushikubi, F. (1999) Prostanoid receptors: structures, properties, and functions. Physiol. Rev. 79, 1193-1226. |
22 | Berges-Gimeno, M. P., Simon, R. A. and Stevenson, D. D. (2002) The natural history and clinical characteristics of aspirin-exacerbated respiratory disease. Ann. Allergy Asthma. Immunol. 89, 474-478. DOI ScienceOn |
23 | Higashi, N., Taniguchi, M., Mita, H., Osame, M. and Akiyama, K. (2002) A comparative study of eicosanoid concentrations in sputum and urine in patients with aspirin-intolerant asthma. Clin. Exp. Allergy 32, 1484-1490. DOI |
24 | Zeitz, H. J. (1988) Bronchial asthma, nasal polyps, and aspirin sensitivity: Samter's syndrome. Clin. Chest. Med. 9, 567-576 |
25 | Hedman, J., Kaprio, J., Poussa, T. and Nieminen, M. M. (1999) Prevalence of asthma, aspirin intolerance, nasal polyposis and chronic obstructive pulmonary disease in a population-based study. Int. J. Epidemiol. 28, 717-722. DOI |
26 | Szczeklik, A. and Stevenson, D. D. (1999) Aspirin-induced asthma: advances in pathogenesis and management. J. Allergy Clin. Immunol. 104, 5-13. DOI ScienceOn |
27 | Picado, C. (2002) Aspirin-intolerant asthma: role of cyclo-oxygenase enzymes. Allergy 57(Suppl 72), 58-60. |
28 | Sampson, A., Holgate, S. Austen, K. F. and Szczeklik, A. (1998) Cyclo-oxygenase. Thorax. 53, 719-720. |
29 | Pierzchalska, M., Szabo, Z., Sanak, M., Soja, J. and Szczeklik, A. (2003) Deficient prostaglandin E2 production by bronchial fibroblasts of asthmatic patients, with special reference to aspirin-induced asthma. J. Allergy Clin. Immunol. 111, 1041-1048. DOI ScienceOn |
30 | Cowburn, A. S., Sladek, K., Soja, J., Adamek, L., Nizankowska, E., Szczeklik, A., Lam, B. K., Penrose, J. F., Austen, F. K., Holgate, S. T. and Sampson, A. P. (1998) Overexpression of leukotriene C4 synthase in bronchial biopsies from patients with aspirin-intolerant asthma. J. Clin. Invest. 101, 834-846. DOI ScienceOn |
31 | Jenkins, C., Costello, J. and Hodge, L. (2004) Systematic review of prevalence of aspirin induced asthma and its implications for clinical practice. BMJ 328, 434. DOI ScienceOn |
32 | Lam, B. K. and Frank Austen, K. (2000) Leukotriene C4 synthase. A pivotal enzyme in the biosynthesis of the cysteinyl leukotrienes. Am. J. Respir. Crit. Care. Med. 161, S16-19. DOI |
33 | Samter, M. and Beers, R. F., Jr. (1967) Concerning the nature of intolerance to aspirin. J. Allergy 40, 281-293. DOI |
34 | Szczeklik, A. and Stevenson, D. D. (2003) Aspirin-induced asthma: advances in pathogenesis, diagnosis, and management. J. Allergy Clin. Immunol. 111, 913-921. DOI ScienceOn |
![]() |