[KSCI] Korea Science Citation Index Service

http://dx.doi.org/10.4014/jmb.2207.07062

Fructan Biosynthesis by Yeast Cell Factories

Hyunjun Ko (Synthetic Biology & Bioengineering Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB))
Bong Hyun Sung (Synthetic Biology & Bioengineering Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB))
Mi-Jin Kim (Synthetic Biology & Bioengineering Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB))
Jung-Hoon Sohn (Synthetic Biology & Bioengineering Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB))
Jung-Hoon Bae (Synthetic Biology & Bioengineering Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB))

Publication Information

Journal of Microbiology and Biotechnology / v.32, no.11, 2022 , pp. 1373-1381 More about this Journal

Abstract

Fructan is a polysaccharide composed of fructose and can be classified into several types, such as inulin, levan, and fructo-oligosaccharides, based on their linkage patterns and degree of polymerization. Owing to its structural and functional diversity, fructan has been used in various fields including prebiotics, foods and beverages, cosmetics, and pharmaceutical applications. With increasing interest in fructans, efficient and straightforward production methods have been explored. Since the 1990s, yeast cells have been employed as producers of recombinant enzymes for enzymatic conversion of fructans including fructosyltransferases derived from various microbes and plants. More recently, yeast cell factories are highlighted as efficient workhorses for fructan production by direct fermentation. In this review, recent advances and strategies for fructan biosynthesis by yeast cell factories are discussed.

Keywords

Fructan; levan; inulin; fructosyltransferase; yeast; fermentation;

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Times Cited By KSCI : 3 (Citation Analysis)

Reference
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