Production of ʟ-Theanine Using Escherichia coli Whole-Cell Overexpressing γ-Glutamylmethylamide Synthetase with Baker's Yeast |
Yang, Soo-Yeon
(Department of Biological Engineering, College of Engineering, Konkuk University)
Han, Yeong-Hoon (Department of Biological Engineering, College of Engineering, Konkuk University) Park, Ye-Lim (Department of Biological Engineering, College of Engineering, Konkuk University) Park, Jun-Young (Department of Biological Engineering, College of Engineering, Konkuk University) No, So-young (Department of Biological Engineering, College of Engineering, Konkuk University) Jeong, Daham (Department of Bioscience and Biotechnology, Konkuk University) Park, Saerom (Department of Biological Engineering, College of Engineering, Konkuk University) Park, Hyung Yeon (Department of Biological Engineering, College of Engineering, Konkuk University) Kim, Wooseong (College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University Seoul) Seo, Seung-Oh (Department of Food Science and Nutrition, The Catholic University of Korea) Yang, Yung-Hun (Department of Biological Engineering, College of Engineering, Konkuk University) |
1 | Zheng G, Sayama K, Okubo T, Juneja LR, Oguni I. 2004. Anti-obesity effects of three major components of green tea, catechins, caffeine and theanine, in mice. In Vivo 18: 55-62. |
2 | Turkozu D, Sanlier N. 2017. L-theanine, unique amino acid of tea, and its metabolism, health effects, and safety. Crit. Rev. Food Sci. Nutr. 57: 1681-1687. DOI |
3 | Saeed M, Naveed M, Arif M, Kakar MU, Manzoor R, Abd El-Hack ME, et al. 2017. Green tea (Camellia sinensis) and l-theanine: Medicinal values and beneficial applications in humans-A comprehensive review. Biomed. Pharmacother. 95: 1260-1275. DOI |
4 | Adhikary R, Mandal V. 2017. L-theanine: A potential multifaceted natural bioactive amide as health supplement. Asian Pac. J. Trop. Biomed. 7: 842-848. DOI |
5 | Moon Y-M, Gurav R, Kim J, Hong Y-G, Bhatia SK, Jung H-R, et al. 2018. Whole-cell immobilization of engineered Escherichia coli JY001 with barium-alginate for itaconic acid production. Biotechnol. Bioprocess Eng. 23: 442-447. DOI |
6 | Bhatia SK, Shim Y-H, Jeon J-M, Brigham CJ, Kim Y-H, Kim H-J, et al. 2015. Starch based polyhydroxybutyrate production in engineered Escherichia coli. Bioprocess Biosys. Eng. 38: 1479-1484. DOI |
7 | Bhatia SK, Kim S-H, Yoon J-J, Yang Y-H. 2017. Current status and strategies for second generation biofuel production using microbial systems. Energy Convers. Manage 148: 1142-1156. DOI |
8 | Alaiz M, Navarro JL, Giron J, Vioque E. 1992. Amino acid analysis by high-performance liquid chromatography after derivatization with diethyl ethoxymethylenemalonate. J. Chromatogr. 591: 181-186. DOI |
9 | Kim J, Seo H-M, Bhatia SK, Song H-S, Kim J-H, Jeon J-M, et al. 2017. Production of itaconate by whole-cell bioconversion of citrate mediated by expression of multiple cis-aconitate decarboxylase (cadA) genes in Escherichia coli. Sci. Rep. 7: 39768. DOI |
10 |
Griffiths MW, Muir DD. 1978. Properties of a thermostable |
11 | Buchachenko AL, Kuznetsov DA. 2008. Magnetic field affects enzymatic ATP synthesis. J. Am. Chem. Soc. 130: 12868-12869. DOI |
12 | Moon Y-M, Yang SY, Choi TR, Jung H-R, Song H-S, hoon Han Y, et al. 2019. Enhanced production of cadaverine by the addition of hexadecyltrimethylammonium bromide to whole cell system with regeneration of pyridoxal-5'-phosphate and ATP. Enzyme Microb. Technol. 127: 58-64. DOI |
13 | Lee SG, Lee JO, Yi JK, Kim BG. 2002. Production of cytidine 5'-monophosphate N-acetylneuraminic acid using recombinant Escherichia coli as a biocatalyst. Biotechnol. Bioeng. 80: 516-524. DOI |
14 | Berke W, Schuz HJ, Wandrey C, Morr M, Denda G, Kula MR. 1988. Continuous regeneration of ATP in enzyme membrane reactor for enzymatic syntheses. Biotechnol. Bioeng. 32: 130-139. DOI |
15 | Endo T, Koizumi S. 2001. Microbial conversion with cofactor regeneration using genetically engineered bacteria. Adv. Synth. Catal. 343: 521-526. DOI |
16 | Moon Y-M, Yang SY, Choi TR, Jung H-R, Song H-S, hoon Han Y, et al. 2019. Enhanced production of cadaverine by the addition of hexadecyltrimethylammonium bromide to whole cell system with regeneration of pyridoxal-5'-phosphate and ATP. Enzyme Microb. Technol. 127: 58-64. DOI |
17 | Taylor RG, Walker DC, McInnes R. 1993. E. coli host strains significantly affect the quality of small scale plasmid DNA preparations used for sequencing. Nucleic Acids Res. 21: 1677. DOI |
18 | Lobstein J, Emrich CA, Jeans C, Faulkner M, Riggs P, Berkmen M. 2012. SHuffle, a novel Escherichia coli protein expression strain capable of correctly folding disulfide bonded proteins in its cytoplasm. Microb. Cell Fact. 11: 753. DOI |
19 | Jakoby M, Ngouoto-Nkili C-E, Burkovski A. 1999. Construction and application of new Corynebacterium glutamicum vectors. Biotechnol. Tech. 13: 437-441. DOI |
20 | Wei LL, Goux WJ. 1992. ATP cofactor regeneration via the glycolytic pathway. Bioorg. Chem. 20: 62-66. DOI |
21 | Sato M, Masuda Y, Kirimura K, Kino K. 2007. Thermostable ATP regeneration system using polyphosphate kinase from Thermosynechococcus elongatus BP-1 for D-amino acid dipeptide synthesis. J. Biosci. Bioeng. 103: 179-184. DOI |
22 | Kameda A, Shiba T, Kawazoe Y, Satoh Y, Ihara Y, Munekata M, et al. 2001. A novel ATP regeneration system using polyphosphate-AMP phosphotransferase and polyphosphate kinase. J. Biosci. Bioeng. 91: 557-563. DOI |
23 | Yan B, Ding Q, Ou L, Zou Z. 2014. Production of glucose-6-phosphate by glucokinase coupled with an ATP regeneration system. World J. Microbiol. Biotechnol. 30: 1123-1128. DOI |
24 | Resnick SM, Zehnder AJ. 2000. In vitro ATP regeneration from polyphosphate and AMP by polyphosphate: AMP phosphotransferase and adenylate kinase from Acinetobacter johnsonii 210A. Appl. Environ. Microbiol. 66: 2045-2051. DOI |
25 | Wakisaka S, Ohshima Y, Ogawa M, Tochikura T, Tachiki T. 1998. Characteristics and efficiency of glutamine production by coupling of a bacterial glutamine synthetase reaction with the alcoholic fermentation system of baker's yeast. Appl. Environ. Microbiol. 64: 2952-2957. DOI |
26 | Shuai Y, Zhang T, Jiang B, Mu W. 2010. Development of efficient enzymatic production of theanine by gamma-glutamyltranspeptidase from a newly isolated strain of Bacillus subtilis, SK11.004. J. Sci. Food Agric. 90: 2563-2567. DOI |
27 | Vuong QV, Stathopoulos CE, Golding JB, Nguyen MH, Roach PD. 2011. Optimum conditions for the water extraction of L-theanine from green tea. J. Sep. Sci. 34: 2468-2474. DOI |
28 | Vuong QV, Bowyer MC, Roach PD. 2011. L-Theanine: properties, synthesis and isolation from tea. J. Sci. Food Agric. 91: 1931-1939. DOI |
29 | Kawagishi H, Sugiyama K. 1992. Facile and large-scale synthesis of L-Theanine. Biosci. Biotechnol. Biochem. 56: 689. DOI |
30 | Tachiki T, Yamada T, Mizuno K, Ueda M, Shiode J, Fukami H. 1998. gamma-glutamyl transfer reactions by glutaminase from Pseudomonas nitroreducens IFO 12694 and their application for the syntheses of theanine and gamma-glutamylmethylamide. Biosci. Biotechnol. Biochem. 62: 1279-1283. DOI |
31 | Mu W, Zhang T, Jiang B. 2015. An overview of biological production of L-theanine. Biotechnol. Adv. 33: 335-342. DOI |
32 |
Chen X, Su L, Wu D, Wu J. 2014. Application of recombinant Bacillus subtilis |
33 | Pu H, Wang Q, Zhu F, Cao X, Xin Y, Luo L, et al. 2013. Cloning, expression of glutaminase from Pseudomonas nitroreducens and application to theanine synthesis. Biocatal. Biotransform. 31: 1-7. DOI |
34 | Sharma E, Joshi R, Gulati A. 2018. l-Theanine: An astounding sui generis integrant in tea. Food Chem. 242: 601-610. DOI |
35 |
Liu S, Li Y, Zhu J. 2016. Enzymatic production of l-theanine by |
36 | Lin J-P, Tian J, You J-F, Jin Z-H, Xu Z-N, Cen P-L. 2004. An effective strategy for the co-production of S-adenosyl-L-methionine and glutathione by fed-batch fermentation. Biochem. Eng. J. 21: 19-25. DOI |
37 | Horinouchi N, Sakai T, Kawano T, Matsumoto S, Sasaki M, Hibi M, et al. 2012. Construction of microbial platform for an energyrequiring bioprocess: practical 2'-deoxyribonucleoside production involving a C- C coupling reaction with high energy substrates. Microb. Cell Fact. 11: 82. DOI |
38 | Matsuno R, Asada M, Nakanishi K, Kamikubo T. 1982. ATP Regeneration by Enzymes of Alcohol Fermentation and Kinases of Yeast and its Computer Simulation, pp. 351-352. Enzyme Engineering, Ed. Springer |
39 | Horinouchi N, Ogawa J, Kawano T, Sakai T, Saito K, Matsumoto S, et al. 2006. Efficient production of 2-deoxyribose 5-phosphate from glucose and acetaldehyde by coupling of the alcoholic fermentation system of Baker's yeast and deoxyriboaldolase-expressing Escherichia coli. Biosci. Biotechnol. Biochem. 70: 1371-1378. DOI |
40 | Yamamoto S, Wakayama M, Tachiki T. 2005. Theanine production by coupled fermentation with energy transfer employing Pseudomonas taetrolens Y-30 glutamine synthetase and baker's yeast cells. Biosci. Biotechnol. Biochem. 69: 784-789. DOI |
41 | Bhatia SK, Bhatia RK, Yang Y-H. 2016. Biosynthesis of polyesters and polyamide building blocks using microbial fermentation and biotransformation. Rev. Environ. Sci. Bio/Technol. 15: 639-663. DOI |
42 |
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