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http://dx.doi.org/10.4014/jmb.1812.12018

Comparison of the Stability of Poly-γ-Glutamate Hydrogels Prepared by UV and γ-Ray Irradiation  

Park, Sang-Joon (Department of Bio and Fermentation Convergence Technology, BK21 PLUS Project, Kookmin University)
Uyama, Hiroshi (Department of Applied Chemistry, Graduate School of Engineering, Osaka University)
Kwak, Mi-Sun (Department of Bio and Fermentation Convergence Technology, BK21 PLUS Project, Kookmin University)
Sung, Moon-Hee (Department of Bio and Fermentation Convergence Technology, BK21 PLUS Project, Kookmin University)
Publication Information
Journal of Microbiology and Biotechnology / v.29, no.7, 2019 , pp. 1078-1082 More about this Journal
Abstract
Poly-${\gamma}$-glutamate (${\gamma}$-PGA) has various applications due to its desirable characteristics in terms of safety and biodegradability. Previous studies have been conducted on ${\gamma}$-PGA hydrogels produced by ${\gamma}$-ray irradiation, but these hydrogels have proved unstable in solutions. This study was conducted to enable the ${\gamma}$-PGA hydrogel to maintain a stable form in solutions. The ${\gamma}$-PGA mixture for UV-irradiation was prepared with a cross-linker (N,N,N-trimethyl-3-[(2-methylacryloyl)amino]propan-1-aminium). Both ${\gamma}$-PGA hydrogels' characteristics, including stability in solutions, were examined. The UV-irradiated ${\gamma}$-PGA hydrogel maintained a stable form during the nine weeks of the study, but the ${\gamma}$-ray irradiated hydrogel dissolved after one week.
Keywords
Viscoelasticity; stability; Poly-${\gamma}$-glutamate; UV-irradiated hydrogel; ${\gamma}$-ray irradiated hydrogel; Bacillus sp.;
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