Cooperative Interactions between Toll-Like Receptor 2 and Toll-Like Receptor 4 in Murine Klebsiella pneumoniae Infections |
Jeon, Hee-Yeon
(Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University)
Park, Jong-Hyung (Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University) Park, Jin-Il (Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University) Kim, Jun-Young (Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University) Seo, Sun-Min (Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University) Ham, Seung-Hoon (Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University) Jeong, Eui-Suk (Laboratory Animal Center, Daegu-Gyeongbuk Medical Innovation Foundation) Choi, Yang-Kyu (Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University) |
1 | Vincent JL, Zhang H, Szabo C, Preiser JC. 2000. Effects of nitric oxide in septic shock. Am. J. Respir. Crit. Care Med. 161: 1781-1785. DOI |
2 | Tsai WC, Strieter RM, Zisman DA, Wilkowski JM, Bucknell KA, Chen GH, et al. 1997. Nitric oxide is required for effective innate immunity against Klebsiella pneumoniae. Infect. Immun. 65: 1870-1875. |
3 | Gregory SH, Wing EJ, Hoffman RA, Simmons RL. 1993. Reactive nitrogen intermediates suppress the primary immunologic response to Listeria. J. Immunol. 150: 2901-2909. |
4 | Wieland CW, Stegenga ME, Florquin S, Fantuzzi G, van der Poll T. 2006. Leptin and host defense against gram-positive and gram-negative pneumonia in mice. Shock 25: 414-419. DOI |
5 | March C, Moranta D, Regueiro V, Llobet E, Tomas A, Garmendia J, et al. 2011. Klebsiella pneumoniae outer membrane protein A is required to prevent the activation of airway epithelial cells. J. Biol. Chem. 286: 9956-9967. DOI |
6 | Jeannin P, Magistrelli G, Goetsch L, Haeuw JF, Thieblemont N, Bonnefoy JY, et al. 2002. Outer membrane protein A (OmpA): a new pathogen-associated molecular pattern that interacts with antigen presenting cells-impact on vaccine strategies. Vaccine 20 (Suppl 4): A23-A27. DOI |
7 | Sabroe I, Prince LR, Jones EC, Horsburgh MJ, Foster SJ, Vogel SN, et al. 2003. Selective roles for Toll-like receptor (TLR) 2 and TLR4 in the regulation of neutrophil activation and life span. J. Immunol. 170: 5268-5275. DOI |
8 | Warger T, Hilf N, Rechtsteiner G, Haselmayer P, Carrick DM, Jonuleit H, et al. 2006. Interaction of TLR2 and TLR4 ligands with the N-terminal domain of Gp96 amplifies innate and adaptive immune responses. J. Biol. Chem. 281: 22545-22553. DOI |
9 | Kovach MA, Standiford TJ. 2001. Toll like receptors in diseases of the lung. Int. Immunopharmacol. 11: 1399-1406. |
10 | Laichalk LL, Kunkel SL, Strieter RM, Danforth JM, Bailie MB, Standiford TJ. 1996. Tumor necrosis factor mediates lung antibacterial host defense in murine Klebsiella pneumonia. Infect. Immun. 64: 5211-5218. |
11 | Bhan U, Ballinger MN, Zeng X, Newstead MJ, Cornicelli MD, Standiford TJ. 2010. Cooperative interactions between TLR4 and TLR9 regulate interleukin 23 and 17 production in a murine model of gram-negative bacterial pneumonia. PLoS One 5: e9896. DOI |
12 | Elson G, Dunn-Siegrist I, Daubeuf B, Pugin J. 2007. Contribution of Toll-like receptors to the innate immune response to gramnegative and gram-positive bacteria. Blood 109: 1574-1583. DOI |
13 | Barton BE, Jackson JV. 1993. Protective role of interleukin 6 in the lipopolysaccharide-galactosamine septic shock model. Infect. Immun. 61: 1496-1499. |
14 | Hurst SM, Wilkinson TS, McLoughlin RM, Jones S, Horiuchi S, Yamamoto N, et al. 2001. Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation. Immunity 14: 705-714. DOI |
15 | Balamayooran G, Batra S, Theivanthiran B, Cai S, Pacher P, Jeyaseelan S. 2012. Intrapulmonary G-CSF rescues neutrophil recruitment to the lung and neutrophil release to blood in gram-negative bacterial infection in MCP-1-/-mice. J. Immunol. 189: 5849-5859. DOI |
16 | Greenberger MJ, Strieter RM, Kunkel SL, Danforth JM, Laichalk LL, McGillicuddy DC, et al. 1996. Neutralization of macrophage inflammatory protein-2 attenuates neutrophil recruitment and bacterial clearance in murine Klebsiella pneumonia. J. Infect. Dis. 173: 159-165. DOI |
17 | De Filippo K, Henderson RB, Laschinger M, Hogg N. 2008. Neutrophil chemokines KC and macrophage-inflammatory protein-2 are newly synthesized by tissue macrophages using distinct TLR signaling pathways. J. Immunol. 180: 4308-4315. DOI |
18 | Moore TA, Perry ML, Getsoian AG, Newstead MW, Standiford TJ. 2002. Divergent role of gamma interferon in a murine model of pulmonary versus systemic Klebsiella pneumoniae infection. Infect. Immun. 70: 6310-6318. DOI |
19 | Podschun R, Ullmann U. 1998. Klebsiella spp. as nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors. Clin. Microbiol. Rev. 11: 589-603. |
20 | Paczosa MK, Mecsas J. 2016. Klebsiella pneumoniae: going on the offense with a strong defense. Microbiol. Mol. Biol. Rev. 80: 629-661. DOI |
21 | Plitas G, Burt BM, Nguyen HM, Bamboat ZM, DeMatteo RP. 2008. Toll-like receptor 9 inhibition reduces mortality in polymicrobial sepsis. J. Exp. Med. 205: 1277-1283. DOI |
22 | Marriott HM, Ali F, Read RC, Mitchell TJ, Whyte MK, Dockrell DH. 2004. Nitric oxide levels regulate macrophage commitment to apoptosis or necrosis during pneumococcal infection. FASEB J. 18: 1126-1128. DOI |
23 | Cauwels A, Bultinck J, De Zwaef R, Vandendriessche B, Magez S, Brouckaert P. 2014. Nitric oxide production by endotoxin preparations in TLR4-deficient mice. Nitric Oxide 36: 36-43. DOI |
24 | Renckens R, Roelofs JJ, Bonta PI, Florquin S, de Vries CJ, Levi M, et al. 2007. Plasminogen activator inhibitor type 1 is protective during severe gram-negative pneumonia. Blood 109: 1593-1601. DOI |
25 | Bogdan C. 2001. Nitric oxide and the immune response. Nat. Immunol. 2: 907-916. DOI |
26 | Branger J, Knapp S, Weijer S, Leemans JC, Pater JM, Speelman P, et al. 2004. Role of Toll-like receptor 4 in grampositive and gram-negative pneumonia in mice. Infect. Immun. 72: 788-794. DOI |
27 | Regueiro V, Moranta D, Campos MA, Margareto J, Garmendia J, Bengoechea JA. 2009. Klebsiella pneumoniae increases the levels of Toll-like receptors 2 and 4 in human airway epithelial cells. Infect. Immun. 77: 714-724. DOI |
28 | Kobayashi Y. 2010. The regulatory role of nitric oxide in proinflammatory cytokine expression during the induction and resolution of inflammation. J. Leukoc. Biol. 88: 1157-1162. DOI |
29 | Medzhitov R. 2001. Toll-like receptors and innate immunity. Nat. Rev. Immunol. 1: 135-145. DOI |
30 | Pichavant M, Delneste Y, Jeannin P, Fourneau C, Brichet A, Tonnel AB, et al. 2003. Outer membrane protein A from Klebsiella pneumoniae activates bronchial epithelial cells: implication in neutrophil recruitment. J. Immunol. 171: 6697-6705. DOI |
31 | Schwandner R, Dziarski R, Wesche H, Rothe M, Kirschning CJ. 1999. Peptidoglycan-and lipoteichoic acid-induced cell activation is mediated by Toll-like receptor 2. J. Biol. Chem. 274: 17406-17409. DOI |
32 | Wieland CW, van Lieshout MH, Hoogendijk AJ, van der Poll T. 2011. Host defence during Klebsiella pneumonia relies on haematopoietic-expressed Toll-like receptors 4 and 2. Eur. Respir. J. 37: 848-857. DOI |
![]() |