Cloning and Characterization of Ginsenoside-Hydrolyzing β-Glucosidase from Lactobacillus brevis That Transforms Ginsenosides Rb1 and F2 into Ginsenoside Rd and Compound K |
Zhong, Fei-Liang
(Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Ministry of Education, and Department of Chemistry, College of Science, Yanbian University)
Ma, Rui (Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Ministry of Education, and Department of Chemistry, College of Science, Yanbian University) Jiang, Mingliang (Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Ministry of Education, and Department of Chemistry, College of Science, Yanbian University) Dong, Wei-Wei (Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Ministry of Education, and Department of Chemistry, College of Science, Yanbian University) Jiang, Jun (Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Ministry of Education, and Department of Chemistry, College of Science, Yanbian University) Wu, Songquan (Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Ministry of Education, and Department of Chemistry, College of Science, Yanbian University) Li, Donghao (Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Ministry of Education, and Department of Chemistry, College of Science, Yanbian University) Quan, Lin-Hu (Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Ministry of Education, and Department of Chemistry, College of Science, Yanbian University) |
1 |
An DS, Cui CH, Lee HG, Wang L, Kim SC, Lee ST, |
2 |
Bae EA, Choo MK, Park EK, Park SY, Shin HY, Kim DH. 2002. Metabolism of ginsenoside Rc by human intestinal bacteria and its related antiallergic activity. |
3 |
Bae EA, Han MJ, Kim EJ, Kim DH. 2004. Transformation of ginseng saponins to ginsenoside Rh2 by acids and human intestinal bacteria and biological activities of their transformants. |
4 |
Chae S, Kang KA, Chang WY, Kim MJ, Lee SJ, Lee YS, |
5 |
Cheng LQ, Na JR, Kim MK, Bang MH, Yang DC. 2007. Microbial conversion of ginsenoside Rb1 to minor ginsenoside F2 and gypenoside XVII by |
6 |
Kim JK, Cui CH, Liu Q, Yoon MH, Kim SC, Im WT. 2013. Mass production of the ginsenoside Rg3(S) through the combinative use of two glycoside hydrolases. |
7 |
Kim MK, Lee JW, Lee KY, Yang DC. 2005. Microbial conversion of major ginsenoside Rb(1) to pharmaceutically active minor ginsenoside Rd. |
8 |
Lin F, Guo X, Lu W. 2015. Efficient biotransformation of ginsenoside Rb1 to Rd by isolated |
9 |
Kim WY, Kim JM, Han SB, Lee SK, Kim ND, Park MK, |
10 |
Lee SJ, Kim Y, Kim MG. 2015. Changes in the ginsenoside content during the fermentation process using microbial strains. |
11 |
Ni HX, Yu NJ, Yang XH. 2010. The study of ginsenoside on PPARgamma expression of mononuclear macrophage in type 2 diabetes. |
12 |
Park CS, Yoo MH, Noh KH, Oh DK. 2010. Biotransformation of ginsenosides by hydrolyzing the sugar moieties of ginsenosides using microbial glycosidases. |
13 |
Wu JY, Gardner BH, Murphy CI, Seals JR, Kensil CR, Recchia J. 1992. Saponin adjuvant enhancement of antigenspecific immune responses to an experimental HIV-1 vaccine. |
14 |
Quan LH, Kim YJ, Li GH, Choi KT, Yang DC. 2013. Microbial transformation of ginsenoside Rb1 to compound K by |
15 |
Quan LH, Liang Z, Kim HB, Kim SH, Kim SY, Noh YD, Yang DC. 2008. Conversion of ginsenoside Rd to compound K by crude enzymes extracted from |
16 |
Quan LH, Min JW, Yang DU, Kim YJ, Yang DC. 2012. Enzymatic biotransformation of ginsenoside Rb1 to 20(S)-Rg3 by recombinant β-glucosidase from |
17 |
Quan LH, Piao JY, Min JW, Yang DU, Lee HN, Yang DC. 2011. Bioconversion of ginsenoside Rb1 into compound K by |
18 |
Quan LH, Wang C, Jin Y, Wang TR, Kim YJ, Yang DC. 2013. Isolation and characterization of novel ginsenosidehydrolyzing glycosidase from |
19 |
Xie J, Zhao D, Zhao L, Pei J, Xiao W, Ding G, |
20 |
Xu QF, Fang XL, Chen DF. 2003. Pharmacokinetics and bioavailability of ginsenoside Rb1 and Rg1 from |
21 |
Yoshikawa M, Morikawa T, Kashima Y, Ninomiya K, Matsuda H. 2003. Structures of new dammarane-type triterpene saponins from the flower buds of |
![]() |