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http://dx.doi.org/10.4014/jmb.1501.01057

Immune Regulatory Effect of Newly Isolated Lactobacillus delbrueckii from Indian Traditional Yogurt  

Hong, Yi-Fan (Graduate School of Biotechnology and Institute of Life Science and Resources, Kyung Hee University)
Lee, Yoon-Doo (Graduate School of Biotechnology and Institute of Life Science and Resources, Kyung Hee University)
Park, Jae-Yeon (Graduate School of Biotechnology and Institute of Life Science and Resources, Kyung Hee University)
Jeon, Boram (Graduate School of Biotechnology and Institute of Life Science and Resources, Kyung Hee University)
Jagdish, Deepa (Graduate School of Biotechnology and Institute of Life Science and Resources, Kyung Hee University)
Jang, Soojin (Institute Pasteur Korea)
Chung, Dae Kyun (Graduate School of Biotechnology and Institute of Life Science and Resources, Kyung Hee University)
Kim, Hangeun (RNA Inc., College of Life Science, Kyung Hee University)
Publication Information
Journal of Microbiology and Biotechnology / v.25, no.8, 2015 , pp. 1321-1323 More about this Journal
Abstract
Lactic acid bacteria (LAB) are microorganisms that are believed to provide health benefits. Here, we isolated LAB from Indian fermented foods, such as traditional Yogurt and Dosa. LAB from Yogurt most significantly induced TNF-α and IL-1β production, whereas LAB from Dosa induced mild cytokine production. After 16S rRNA gene sequencing and phylogenetic analysis, a Yogurt-borne lactic acid bacterium was identified and classified as Lactobacillus delbrueckii subsp. bulgaricus, and it was renamed L. delbrueckii K552 for the further studies. Our data suggest that the newly isolated L. delbrueckii can be used for the treatment of immune deficiency disorders.
Keywords
Lactic acid bacteria; Lactobacillus delbrueckii; tumor necrosis factor-alpha; interleukin-1beta; Indian fermented foods;
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