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http://dx.doi.org/10.4014/jmb.1107.07028

Association of Colony Morphology with Coenzyme $Q_{10}$ Production and Its Enhancement from Rhizobium radiobacter T6102W by Addition of Isopentenyl Alcohol as a Precursor  

Seo, Myung-Ji (Fermentation and Functionality Research Group, Korea Food Research Institute)
Kook, Moo-Chang (Department of Marine Biotechnology, Anyang University)
Kim, Soon-Ok (Division of Research and Product Development, Union Korea Pharm., Co. Ltd.)
Publication Information
Journal of Microbiology and Biotechnology / v.22, no.2, 2012 , pp. 230-233 More about this Journal
Abstract
Rhizobium radiobacter T6102 was morphologically purified by the aniline blue agar plates to give two distinct colonies; white smooth mucoid colony (T6102W) and blue rough colony (T6102B). The coenzyme $Q_{10}$ ($CoQ_{10}$) was produced just by T6102W, showing 2.0 mg/g of $CoQ_{10}$ content, whereas the T6102B did not produce the $CoQ_{10}$. All of the used $CoQ_{10}$ biosynthetic precursors enhanced the $CoQ_{10}$ production by T6102W. Specifically, the supplementation of 0.75 mM isopentenyl alcohol improved the $CoQ_{10}$ concentration (19.9 mg/l) and content (2.4 mg/g) by 42% and 40%, respectively.
Keywords
Aniline blue; coenzyme $Q_{10}$; isopentenyl alcohol; Rhizobium radiobacter;
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