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http://dx.doi.org/10.4014/jmb.1010.10019

Comparison of tdcA Expression Between Escherichia coli and Salmonella enterica Serovar Typhimurium  

Kim, Min-Jeong (Radiation Research Division for Biotechnology, Korea Atomic Energy Research Institute)
Lim, Sang-Yong (Radiation Research Division for Biotechnology, Korea Atomic Energy Research Institute)
Ryu, Sang-Ryeol (Department of Food and Animal Biotechnology, School of Agricultural Biotechnology, and Center for Agricultural Biomaterials, Seoul National University)
Publication Information
Journal of Microbiology and Biotechnology / v.21, no.3, 2011 , pp. 252-255 More about this Journal
Abstract
Both Escherichia coli (E. coli) and Salmonella enterica serovar Typhimurium (S. Typhimurium) have a tdc operon that encodes enzymes involved in a metabolic pathway for the degradation of L-serine and L-threonine. However, S. Typhimurium does not have the tdcR gene, which is a positive regulator in E. coli. In the present study, transcriptional analysis revealed that tdcA expression in E. coli is higher under anaerobic than aerobic growth conditions, but the opposite is true in S. Typhimurium. Interestingly, a tdcR mutant strain of E. coli showed a similar expression pattern to that observed in S. Typhimurium and was also induced by anaerobic shock. These results suggest that the induction of tdcA expression by anaerobic conditions is observable when tdcA expression is low owing to the absence of TdcR.
Keywords
Escherichia coli; Salmonella Typhimurium; tdcA; tdcR;
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Times Cited By KSCI : 5  (Citation Analysis)
Times Cited By Web Of Science : 1  (Related Records In Web of Science)
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