Multistage Operation of Airlift Photobioreactor for Increased Production of Astaxanthin from Haematococcus pluvialis |
Choi, Yoon-E
(Department of Chemical and Biomolecular Engineering, KAIST)
Yun, Yeoung-Sang (Department of BIN Fusion Technology and School of Chemical Engineering, Chonbuk National University) Park, Jong-Moon (Department of Chemical Engineering, School of Environmental Science and Engineering, Pohang University of Science and Technology) Yang, Ji-Won (Department of Chemical and Biomolecular Engineering, KAIST) |
1 | Fabregas, J., A. Dominguez, D. Alvarez, T. Lamela, and A. Otero. 1998. Induction of astaxanthin accumulation by nitrogen and magnesium deficiencies in Haematococcus pluvialis. Biotechnol. Lett. 20: 623-626. DOI ScienceOn |
2 | Fabregas, J., A. Dominguez, M. Regueiro, A. Maseda, and A. Otero. 2000. Optimization of culture medium for the continuous cultivation of the microalga Haematococcus pluvialis. Appl. Microbiol. Biotechnol. 53: 530-535. DOI ScienceOn |
3 | Fabregas, J., A. Otero, A. Maseda, and A. Dominguez. 2001. Two-stage cultures for the production of astaxanthin from Haematococcus pluvialis. J. Biotechnol. 89: 65-71. DOI ScienceOn |
4 | Goodwin, T. W. 1984. The Biochemistry of the Carotenoids, Vols. 1-2. Chapman and Hall, New York. |
5 | Goodwin, T. W. and M. Jamikorn. 1954. Studies in carotenogenesis. II. Carotenoid synthesis in the alga Haematococcus pluvialis. Biochem. J. 57: 376-381. |
6 | Borowitzka, M. A. 1999. Commercial production of microalgae: Ponds, tanks, tubes, and fermenters. J. Biotechnol. 70: 313-321. DOI ScienceOn |
7 | Boussiba, S. 2000. Carotenogenesis in the green alga Haematococcus pluvialis: Cellular physiology and stress response. Physiol. Plant 108: 111-117. DOI ScienceOn |
8 | Boussiba, S., W. Bing, A. Zarka, J. P. Yuan, and F. Chen. 1999. Changes in pigment profiles of Haematococcus pluvialis during exposure to environmental stresses. Biotechnol. Lett. 21: 601-604. DOI ScienceOn |
9 | Boussiba, S. and A. Vonshak. 1991. Astaxanthin accumulation in the green alga Haematococcus pluvialis. Plant Cell Physiol. 32: 1077-1082. |
10 | Choi, Y. E., Y. S. Yun, and J. M. Park. 2002. Evaluation of factors promoting astaxanthin production by a unicellular green alga, Haematococcus pluvialis, with fractional factorial design. Biotechnol. Prog. 18: 1170-1175. DOI ScienceOn |
11 | Harker, M., A. J. Tsavalos, and A. J. Young. 1995. Use of response surface methodology to optimize carotenogenesis in the microalga Haematococcus pluvialis. J. Appl. Phycol. 7: 399-406. DOI ScienceOn |
12 | Davies, B. H. 1976. Carotenoids, pp. 38-165. In: Chemistry and Biochemistry of Plant Pigments, 2nd Ed. Academic Press, London. |
13 | Kobayashi, M., T. Kakizono, N. Nishio, and S. Nagai. 1992. Effects of light intensity, light quality, and illumination cycle on astaxanthin formation in a green alga Haematococcus pluvialis. J. Ferment. Bioeng. 74: 61-63. DOI ScienceOn |
14 | Kobayashi, M., Y. Kurimura, T. Kakizono, N. Nishio, and Y. Tsuji. 1997. Morphological changes in the life cycle of the green alga Haematococcus pluvialis. J. Ferment. Bioeng. 84: 94-97. DOI ScienceOn |
15 | Kobayashi, M., K. Toshide, and S. Nagai. 1991. Astaxanthin production by a green alga Haematococcus pluvialis accompanied with morphological changes in acetate media. J. Ferment. Bioeng. 75: 335-339. |
16 | Lee, Y. K. 2001. Microalgal mass culture systems and methods: Their limitation and potential. J. Appl. Phycol. 13: 307-315. DOI ScienceOn |
17 | Lorenz, R. T. and G. R. Cysewski. 2000. Commercial potential for Haematococcus microalgae as a natural source of astaxanthin. Trends Biotechnol. 18: 160-167. DOI ScienceOn |
18 | Meyers, S. P. 1994. Developments in world aquaculture, feed formulations, and role of carotenoids. Pure Appl. Chem. 66: 1069-1076. DOI ScienceOn |
19 | Harker, M., A. J. Tsavalos, and A. J. Young. 1996. Factors responsible for astaxanthin formation in the Chlorophyte Haematococcus pluvialis. Bioresource Technol. 55: 207-214. DOI ScienceOn |
20 | Kakizono, T., M. Kobayashi, and S. Nagai. 1992. Effect of carbon/nitrogen ratio on encystment accompanied with astaxanthin formation in a green alga Haematococcus pluvialis. J. Ferment. Bioeng. 74: 403-405. DOI ScienceOn |
21 | Kobayashi, M., T. Kakizono, and S. Nagai. 1993. Enhanced carotenoid biosynthesis by oxidative stress in acetate-induced cyst cells of a green unicellular alga Haematococcus pluvialis. Appl. Environ. Microbiol. 59: 867-873. |
22 | Suh, I. S. and S. B. Lee. 2001. Cultivation of a cyanobacterium in an internally radiating air-lift photobioreactor. J. Appl. Phycol. 13: 381-388. DOI ScienceOn |
23 | Ogbonna, J. C., H. Yada, H. Masui, and H. Tanaka. 1996. A novel internally illuminated stirred tank photobioreactor for large-scale cultivation of photosynthetic cells. J. Ferment. Bioeng. 82: 61-67. DOI ScienceOn |
24 | Palozza, P. and N. I. Krinsky. 1992. Astaxanthin and canthaxanthin are potent antioxidants in a membrane model. Arch. Biochem. Biophys. 197: 291-295. |
25 | Richmond, A. 2000. Microalgal biotechnology at the turn of the millennium: A personal view. J. Appl. Phycol. 12: 441-451. DOI ScienceOn |
26 | Yun, Y. S. and J. M. Park. 2001. Attenuation of monochromatic and polychromatic lights in Chlorella vulgaris suspension. Appl. Microbiol. Biotechnol. 55: 765-770. DOI ScienceOn |