Towards Methionine Overproduction in Corynebacterium glutamicum - Methanethiol and Dimethyldisulfide as Reduced Sulfur Sources |
Bolten, Christoph J.
(Biochemical Engineering Institute, Technische Universitat Braunschweig)
Schroder, Hartwig (BASF SE, Research Fine Chemicals and Biotechnology) Dickschat, Jeroen (Organic Chemistry Institute, Technische Universitat Braunschweig) Wittmann, Christoph (Biochemical Engineering Institute, Technische Universitat Braunschweig) |
1 | Kromer, J. O., E. Heinzle, H. Schröder, and C. Wittmann. 2006. Accumulation of homolanthionine and activation of a novel pathway for isoleucine biosynthesis in Corynebacterium glutamicum McbR deletion strains. J. Bacteriol. 188: 609-618. DOI ScienceOn |
2 | Bolten, C. J., P. Kiefer, F. Letisse, J. C. Portais, and C. Wittmann. 2007. Sampling for metabolome analysis of microorganisms. Anal. Chem. 79: 3843-3849. DOI ScienceOn |
3 | Kiefer, P., E. Heinzle, O. Zelder, and C. Wittmann. 2004. Comparative metabolic flux analysis of lysine-producing Corynebacterium glutamicum cultured on glucose or fructose. Appl. Environ. Microbiol. 70: 229-239. DOI ScienceOn |
4 | Becker, J., C. Klopprogge, A. Herold, O. Zelder, C. J. Bolten, and C. Wittmann. 2007. Metabolic flux engineering of L-lysine production in Corynebacterium glutamicum - over expression and modification of G6P dehydrogenase. J. Biotechnol. 132: 99-109. DOI ScienceOn |
5 | Foglino, M., F. Borne, M. Bally, G. Ball, and J. C. Patte. 1995. A direct sulfhydrylation pathway is used for methionine biosynthesis in Pseudomonas aeruginosa. Microbiology 141: 431-439. DOI ScienceOn |
6 | Dickschat, J. S., T. Martens, T. Brinkhoff, M. Simon, and S. Schulz. 2005. Volatiles released by a Streptomyces species isolated from the North Sea. Chem. Biodivers. 2: 837-865. DOI ScienceOn |
7 | Flavin, M. and C. Slaughter. 1967. Enzymatic synthesis of homocysteine or methionine directly from O-succinyl-homoserine. Biochim. Biophys. Acta 132: 400-405. DOI ScienceOn |
8 | Becker, J., C. Klopprogge, O. Zelder, E. Heinzle, and C. Wittmann. 2005. Amplified expression of fructose 1,6-bisphosphatase in Corynebacterium glutamicum increases in vivo flux through the pentose phosphate pathway and lysine production on different carbon sources. Appl. Environ. Microbiol. 71: 8587-8596. DOI ScienceOn |
9 | Bonnarme, P., L. Psoni, and H. E. Spinnler. 2000. Diversity of L-methionine catabolism pathways in cheese-ripening bacteria. Appl. Environ. Microbiol. 66: 5514-5517. DOI ScienceOn |
10 | Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-254. DOI ScienceOn |
11 | Becker, J., C. Klopprogge, H. Schröder, and C. Wittmann. 2009. Tricarboxylic acid cycle engineering for improved lysine production in Corynebacterium glutamicum. Appl. Environ. Microbiol. 75: 7866-7869. DOI ScienceOn |
12 | Wittmann, C. 2007. Fluxome analysis using GC-MS. Microb. Cell Fact 6: 6. DOI |
13 | Wittmann, C., P. Kiefer, and O. Zelder. 2004. Metabolic fluxes in Corynebacterium glutamicum during lysine production with sucrose as carbon source. Appl. Environ. Microbiol. 70: 7277-7287. DOI ScienceOn |
14 | Wittmann, C., J. O. Krömer, P. Kiefer, T. Binz, and E. Heinzle. 2004. Impact of the cold shock phenomenon on quantification of intracellular metabolites in bacteria. Anal. Biochem. 327: 135-139. DOI ScienceOn |
15 | Yamagata, S. 1971. Homocysteine synthesis in yeast. Partial purification and properties of O-acetylhomoserine sulfhydrylase. J. Biochem. (Tokyo) 70: 1035-1045. DOI |
16 | Mondal, S., Y. B. Das, and S. P. Chatterjee. 1996. Methionine production by microorganisms. Folia Microbiol. (Praha) 41: 465-472. DOI ScienceOn |
17 | Park, S. D., J. Y. Lee, S. Y. Sim, Y. Kim, and H. S. Lee. 2007. Characteristics of methionine production by an engineered Corynebacterium glutamicum strain. Metab. Eng. 9: 327-336. DOI ScienceOn |
18 | Wittmann, C. and J. Becker. 2007. The L-lysine story: From metabolic pathways to industrial production. Microbiol. Monogr. 5: 39-70. DOI |
19 | Lee, H. S. and B. J. Hwang. 2003. Methionine biosynthesis and its regulation in Corynebacterium glutamicum: Parallel pathways of transsulfuration and direct sulfhydrylation. Appl. Microbiol. Biotechnol. 62: 459-467. DOI ScienceOn |
20 | Lee, H. S. 2005. Sulfur metabolism and its regulation, pp. 351- 376. In L. Eggeling and M. Bott (eds.). Handbook of Corynebacterium glutamicum. CRC Press, Boca Raton. |
21 | Kromer, J. O., M. Fritz, E. Heinzle, and C. Wittmann. 2005. In vivo quantification of intracellular amino acids and intermediates of the methionine pathway in Corynebacterium glutamicum. Anal. Biochem. 340: 171-173. DOI ScienceOn |
22 | Mampel, J., H. Schröder, S. Haefner, and U. Sauer. 2005. Single-gene knockout of a novel regulatory element confers methionine resistance and elevates methionine production in Corynebacterium glutamicum. Appl. Microbiol. Biotechnol. 68: 228-236. DOI ScienceOn |
23 | Mondal, S., Y. B. Das, and S. P. Chatterjee. 1994. Improvement of L-methionine production by double auxotrophic mutants of Brevibacterium heali LT5 and LT18. Res. Ind. 39: 239-241. |
24 | Kromer, J. O., C. J. Bolten, E. Heinzle, H. Schröder, and C. Wittmann. 2008. Physiological response of Corynebacterium glutamicum to oxidative stress induced by deletion of the transcriptional repressor McbR. Microbiology 154: 3917-3930. DOI ScienceOn |
25 | Iwatani, S., S. Van Dien, K. Shimbo, K. Kubota, N. Kageyama, D. Iwahata, et al. 2007. Determination of metabolic flux changes during fed-batch cultivation from measurements of intracellular amino acids by LC-MS/MS. J. Biotechnol. 128: 93-111. DOI ScienceOn |
26 | Kromer, J. O., C. Wittmann, H. Schröder, and E. Heinzle. 2006. Metabolic pathway analysis for rational design of L-methionine production by Escherichia coli and Corynebacterium glutamicum. Metab. Eng. 8: 353-369. DOI ScienceOn |
27 | Kanzaki, H., M. Kobayashi, T. Nagasawa, and H. Yamada. 1987. Purification and characterization of cystathionine γ- synthase type II from Bacillus sphaericus. Eur. J. Biochem. 163: 105-112. DOI ScienceOn |
28 | Kiene, R. P., L. J. Linn, J. Gonzalez, M. A. Moran, and J. A. Bruton. 1999. Dimethylsulfoniopropionate and methanethiol are important precursors of methionine and protein-sulfur in marine bacterioplankton. Appl. Environ. Microbiol. 65: 4549-4558. |
29 | Hwang, B. J., H. J. Yeom, Y. Kim, and H. S. Lee. 2002. Corynebacterium glutamicum utilizes both transsulfuration and direct sulfhydrylation pathways for methionine biosynthesis. J. Bacteriol. 184: 1277-1286. DOI ScienceOn |
30 | Ikeda, M. 2003. Amino acid production processes. Adv. Biochem. Eng. Biotechnol. 79: 1-35. |
31 | Dickschat, J. S., H. B. Bode, S. C. Wenzel, R. Muller, and S. Schulz. 2005. Biosynthesis and identification of volatiles released by the myxobacterium Stigmatella aurantiaca. Chembiochem 6: 2023-2033. DOI ScienceOn |