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http://dx.doi.org/10.4014/jmb.0906.06017

Secondary Metabolites of Volvariella bombycina and Their Inhibitory Effects on Melanogenesis  

Xu, Guang-Hua (Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology)
Choo, Soo-Jin (Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology)
Kim, Young-Hee (Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology)
Ryoo, In-Ja (Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology)
Seok, Soon-Ja (Rural Development Administration (RDA), National Institute of Agricultural Science and Technology)
Ahn, Jong-Seog (Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology)
Yoo, Ick-Dong (Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology)
Publication Information
Journal of Microbiology and Biotechnology / v.20, no.1, 2010 , pp. 78-81 More about this Journal
Abstract
Four compounds were isolated from the culture broth of Volvariella bombycina and they were identified as ergosta-4,6,8(14),22-tetraene-3-one (1), ergosterol peroxide (2), indole-3-carboxaldehyde (3), and indazole (4) by interpretation of spectroscopic data. Among them, compound 2 exhibited melanogenesis inhibitory effect in cultured B16 mouse melanoma cells.
Keywords
Melanogenesis; structure elucidation; Volvariella bombycina;
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