Astaxanthin Inhibits -Mediated Apoptotic Cell Death in Mouse Neural Progenitor Cells via Modulation of P38 and MEK Signaling Pathways |
Kim, Jeong-Hwan
(Department of Biomaterial Control, Dong-Eui University)
Choi, Woo-Bong (Department of Biomaterial Control, Dong-Eui University) Lee, Jong-Hwan (Department of Biomaterial Control, Dong-Eui University) Jeon, Sung-Jong (Department of Biomaterial Control, Dong-Eui University) Choi, Yung-Hyun (Department of Biomaterial Control, Dong-Eui University) Kim, Byung-Woo (Department of Biomaterial Control, Dong-Eui University) Chang, Hyo-Ihl (Department of Biotechnology, School of Life Sciences and Biotechnology, Korea University) Nam, Soo-Wan (Department of Biomaterial Control, Dong-Eui University) |
1 | Andrew, A. G., H. J. Phaff, and M. P. Starr. 1976. Carotenoids of Phaffia rhodozyma, a red pigmented fermenting yeast. Phytochemistry 15: 1003-1007 DOI ScienceOn |
2 | Bellavite, P. 1988. The superoxide-forming enzymatic system of phagocytes. Free Radical Biol. Med. 4: 225-261 DOI ScienceOn |
3 | Dexter, D. T., C. J. Carter, F. R. Wells, Y. Javoy-Agid, A. Lees, P. Jenner, and C. D. Marsden. 1989. Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease. J. Neurochem. 52: 381-389 DOI PUBMED |
4 | Johnson, E. A. and M. J. Lewis. 1979. Astaxanthin formation by the yeast Phcffiarhodozyma. J. Gen. Microbiol. 115: 173-183 DOI |
5 | Jyonouchi, H., L. Zhang, M. Gross, and Y. Tomita. 1994. Immunomodulating actions of carotenoids: Enhancement of in vivo and in vitro antibody production to T-dependent antigens. Nutr. Cancer 21: 47-58 DOI ScienceOn |
6 | Lee, S. R., S. Bar-Noy, J. Kwon, R. L. Levine, T. C. Stadtman, and S. G Rhee. 2000. Mammalian thioredoxin reductase: Oxidation of the C-terminal cysteine/selenocysteine active site forms a thioselenide, and replacement of selenium with sulfur markedly reduces catalytic activity. Proc. Natl. Acad. Sci. U.S.A. 97: 2521-2526 DOI ScienceOn |
7 | Tanaka, T., T. Kawamori, M. Ohnishi, H. Makita, H. Mori, K. Satoh, and A. Hara. 1995. Suppression of azoxymethane-induced rat colon carcinogenesis by dietary administration of naturally occurring xanthophylls astaxanthin and canthaxanthin during the postinitiation phase. Carcinogenesis 16: 2957-2963 DOI ScienceOn |
8 | Liu, X., C. N. Kim, Y. Yang, R. Jemmerson, and X. Wang. 1996. Induction of apoptosis program in cell-free extracts: Requirement for dATP and cytochrome c. Cell 86: 145-157 |
9 | Naguib, Y. M. 2000. Antioxidant activities of astaxanthin and related carotenoids. J. Agric. Food Chem. 48: 1150-1154 DOI PUBMED ScienceOn |
10 | Tanaka, T., H. Makita, M. Ohnishi, H. Mori, K. Satoh, and A. Hara. 1995. Chemoprevention of rat oral carcinogenesis by naturally occurring xanthophylls, astaxanthin and canthaxanthin. Cancer Res. 55: 4059-4064 PUBMED |
11 | Mortensen, A., L. H. Skibsted, and T. G. Truscott. 2001. The interaction of dietary carotenoids with radical species. Arch. Biochem. Biophys. 385: 13-19 DOI ScienceOn |
12 | Okai, Y. and K. Higashi-Okai. 1996. Possible immunomodulating activities of carotenoids in in vitro cell culture experiments. Int. J. Immunopharmacol. 8: 753-758 |
13 | Desagher, S. and J. C. Martinou. 2000. Mitochondria as the central control point of apoptosis, Trends Cell Biol. 10: 369-377 DOI ScienceOn |
14 | Nakajima, Y., Y. Inokuchi, M. Shimazawa, K. Otsubo, T. Ishibashi, and H. Hara. 2008. Astaxanthin, a dietary carotenoid, protects retinal cells against oxidative stress in-vitro and in mice in-vivo. J. Pharm. Pharmacol. 60: 1365-1374 DOI ScienceOn |
15 | Cornett, C. R., W. R. Markesbery, and W. D. Ehmann. 1998. Imbalances of the trace elements related to oxidative damage in Alzheimer disease brain. Neurotoxicology 19: 339-345 PUBMED |
16 | Lim, B. P., A. Nagao, J. Terao, K. Tanaka, T. Suzuki, and K. Takama. 1992. Antioxidant activity of xanthophylls on peroxyl radical-mediated phospholipid peroxidation. Biochim. Biophys. Acta 1126: 178-184 DOI PUBMED ScienceOn |
17 | Facchinetti, F., V. L. Dawson, and T. M. Dawson. 1998. Free radicals as mediators of neuronal injury, Cell Mol. Neurobiol. 18: 667-682 DOI ScienceOn |
18 | Halliwell, B. and J. M. Gutteridge. 1992. Biologically relevant metal ion-dependent hydroxyl radical generation: An update. Fed Eur. Biochem. Soc. Lett. 307: 108-112 DOI ScienceOn |
19 | Itoh, N. M., Y. Tsujimoto, and S. Nagata. 1993. Effect of Bcl-2 on Fas antigen-mediated cell death. J. Immunol. 151: 621-627 PUBMED |
20 | Krinsky, N. I. 1989. Antioxidant function of carotenoids. Free Radic. Biol. Med. 7: 617-635 DOI ScienceOn |
21 | Richter, C. and G. E. Kass. 1991. Oxidative stress in mitochondria: Its relationship to cellular homeostasis, cell death, proliferation, and differentiation. Chem. Biol. Interact. 77: 1-23 DOI ScienceOn |
22 | Tanaka, T., Y. Morishita, M. Suzuki, T. Kojima, A. Okumura, and H. Mori. 1994. Chemoprevention of mouse urinary bladder carcinogenesis by the naturally occurring carotenoid astaxanthin. Carcinogenesis 15: 15-19 DOI ScienceOn |
23 | Kluck, R. M., E. Bessy-Wetzel, D. R. Green, and D. D. Newmeywer. 1997. The release of cytochrome c from mitochodria: A primary site tor Bcl-2 regulation of apoptosis. Science 275: 1132-1136 DOI PUBMED ScienceOn |
24 | Palozza, P. and N. I. Krinsky. 1992. Astaxanthin and canthaxanthin are potent antioxidants in a membrane model. Arch. Biochem. Biophys. 297: 291-295 DOI ScienceOn |
25 | Kurashige, M., E. Okimasu, M. Inoue, and K. Utsumi. 1990. Inhibition of oxidative injury of biological membranes by astaxanthin. Physiol. Chem. Phys. Med. NMR 22: 27-38 PUBMED |
26 | Sagara, Y., S. Tan, P. Maher, and D. Schubert. 1998. Mechanisms of resistance to oxidative stress in Alzheimer's disease brain. Neurotoxicology 19: 339-345 PUBMED |
27 | Giulian, D., K. Vaca, and M. Corpuz. 1993. Brain glia release factors with opposing actions upon neuronal survival. J. Neurosci. 13: 29-37 PUBMED |
28 | Murphy, M. P. and R. A. Smith. 2000. Drug delivery to mitochondria: The key to mitochondrial medicine. Adv. Drug Deliv. Rev. 41: 235-250 DOI ScienceOn |
29 | Jyonouchi, H., S. Sun, K. Lijima, and M. D. Gross. 2000. Antitumor activity of astaxanthin and its mode of action. Nutr. Cancer 36: 59-65 DOI ScienceOn |
30 | Yu, B. P. 1994. Cellular defenses against damage from reactive oxygen species. Physiol. Rev. 74: 139-162 PUBMED |
31 | Bruce-Keller, A. J., J. G. Begley, W. Fu, D. A. Butterfield, D. E. Bredesen, J. B. Hutchins, K. Hensley, and M. P. Mattson. 1998. Bcl-2 protects isolated plasma and mitochondrial membranes against lipid peroxidation induced by hydrogen peroxide and amyloid B-peptide. J. Neurochem. 70: 31-39 DOI ScienceOn |
32 | Tan, S., M. Wood, and P. Maher. 1995. Oxidative stress induces a form of programmed cell death with characteristics of both apoptosis and necrosis in neuronal cells. J. Neurochem. 71: 95-105 DOI ScienceOn |
33 | Smith, C. D., J. M. Carney, P. E. Starke-Reed, C. N. Oliver, E. R. Stadtrnan, R. A. Floyd, and W. R. Markesbery. 1991. Excess brain protein oxidation and enzyme dysfunction in normal aging and Alzheimer disease. Proc. Natl. Acad Sci. U.S.A. 88: 10540-10543 DOI ScienceOn |
34 | Ragusa, R. J., C. K. Chow, and J. D. Porter. 1997. Oxidative stress as a potential pathogenic mechanism in an animal model of Duchenne muscular dystrophy. Neuromuscul. Disord 7: 379-386 DOI ScienceOn |
35 | Bendich, A. and J. A. Olson. 1989. Biological actions of carotenoids. FASEB J. 3: 1927-1932 PUBMED |