Overproduction of Recombinant Human VEGF (Vascular Endothelial Growth Factor) in Chinese Hamster Ovary Cells |
Lee, Seong-Baek
(PanGen Biotech Inc.)
Park, Jeong-Soo (PanGen Biotech Inc.) Lee, Seung-Hee (PanGen Biotech Inc.) Park, Jun-Ho (PanGen Biotech Inc.) Yu, Sung-Ryul (Graduate School of Biotechnology, Kyung Hee University) Kim, Hee-Chan (Graduate School of Biotechnology, Kyung Hee University) Kim, Dong-Jun (PanGen Biotech Inc.) Byun, Tae-Ho (PanGen Biotech Inc.) Baek, Kwang-Hee (Graduate School of Biotechnology, Kyung Hee University) Ahn, Young-Joon (School of Agricultural Biotechnology, Seoul National University) Yoon, Jae-Seung (Graduate School of Biotechnology, Kyung Hee University) |
1 | Carmeliet, P. 2003. Angiogenesis in health and disease. Nat. Med. 9: 653-660 DOI ScienceOn |
2 | Ciudad, C. J., G. Urlaub, and L. A. Chasin. 1988. Deletion analysis of the Chinese hamster dihydrofolate reductase gene promoter. J. Biol. Chem. 263: 16274-16282 |
3 | Ferrara, N. 2004. Vascular endothelial growth factor: Basic science and clinical progress. Endocrine Rev. 25: 581-611 DOI ScienceOn |
4 | Henry, T. D., B. H. Annex, G. R. McKendall, M. A. Azrin, J. J. Lopez, F. J. Giordano, P. K. Shah, J. T. Willerson, R. L. Benza, D. S. Berman, C. M. Gibson, A. Bajamonde, A. C. Rundle, E. R. McCluskey; VIVA Investigators. 2003. The VIVA trials: Vascular endothelial growth factor in ischemia for vascular angiogenesis. Circulation 107: 1359-1365 DOI ScienceOn |
5 | Keyt, B. A., L. T. Berleau, H. V. Nguyen, H. Chen, H. Heinsohn, R. Vandlen, and N. Ferrara. 1996. The carboxylterminal domain (111-165) of vascular endothelial growth factor is critical for its mitogenic potency. J. Biol. Chem. 271: 7788-7795 DOI |
6 | Siemeister, G., B. Schnurr, K. Mohrs, C. Schachtele, D. Marme, and G. Martiny-Baron. 1996. Expression of biologically active isoforms of the tumor angiogenesis factor VEGF in Escherichia coli. Biochem. Biophys. Res. Commun. 222: 249-255 DOI ScienceOn |
7 | Plouet, J., F. Moro, S. Bertagnolli, N. Coldeboeuf, H. Mazarguil, S. Clamens, and F. Bayard. 1997. Extracellular cleavage of the vascular endothelial growth factor 189-amino acid form by urokinase is required for its mitogenic effect. J. Biol. Chem. 272: 13390-13396 DOI ScienceOn |
8 | Bhisitkul, R. B. 2006. Vascular endothelial growth factor biology: Clinical implications for ocular treatments. Br. J. Ophthalmol. 90: 1542-1547 DOI ScienceOn |
9 | Kozak, M. 1984. Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs. Nucleic Acids Res. 4: 857-872 |
10 | Park, J., S. Yu, J. Yoon, and K. Baek. 2005. High-level expression of recombinant human bone morphogenetic protein- 4 in Chinese hamster ovary cells. J. Microbiol. Biotechnol. 15: 1397-1401 과학기술학회마을 |
11 | Freedman, S. B. 2002. Clinical trials of gene therapy for atherosclerotic cardiovascular disease. Curr. Opin. Lipidol. 13: 653-661 DOI ScienceOn |
12 | Ferrara, N., H.-P. Gerber, and J. LeCouter. 2003. The biology of VEGF and its receptors. Nat. Med. 9: 669-676 DOI ScienceOn |
13 | Grabenhorst, E., P. Schlenke, S. Pohl, M. Nimtz, and H. S. Conradt. 1999. Genetic engineering of recombinant glycoproteins and the glycosylation pathway in mammalian host cells. Glycoconjugate J. 16: 81-97 DOI ScienceOn |
14 | Risau, W. 1997. Mechnisms of angiogenesis. Nature 386: 671- 674 DOI ScienceOn |
15 | Bae, G. W., D.-W. Jeong, H. J. Kim, G. M. Lee, H. Park, T.-B. Choe, S. Kang, I. Y. Kim, and I.-H. Kim. 2006. High productivity of t-PA in CHO cells using hypoxia response element. J. Microbiol. Biotechnol. 16: 695-703 과학기술학회마을 |
16 | Byun, J., J. M. Heard, J. E. Huh, S. J. Park, E. A. Jung, J. O. Jeong, H. C. Gwon, and D. K. Kim. 2001. Efficient expression of the vascular endothelial growth factor gene in vitro and in vivo, using an adeno-associated virus vector. J. Mol. Cell Cardiol. 33: 295-305 DOI ScienceOn |
17 | Kim, E., D. Kim, H.-Y. Hwang, J. Yoon, Y. Yoon, and K. Baek. 2004. High-level expression of recombinant human interleukin- 2 in Chinese hamster ovary cells using the expression system containing transcription terminator. J. Microbiol. Biotechnol. 14:810-815 |
18 | Yang, R., S. Bunting, A. Ko, B. A. Keyt, N. B. Modi, T. F. Zioncheck, N. Ferrara, and H. Jin. 1998. Substantially attenuated hemodynamic responses to Escherichia coli-derived vascular endothelial growth factor given by intravenous infusion compared with bolus injection. J. Pharmacol. Exp. Ther. 284: 103-110 |
19 | Lee, G. Y., W. W. Jung, C. S. Kang, and I. S. Bang. 2006. Expression and characterization of human endothelial growth factor (VEGF165) in insect cells. Protein Expr. Purif. 46: 503-509 DOI ScienceOn |
20 | Kim, J.-M., J.-S. Kim, D.-H. Park, H. S. Kang, J. Yoon, K. Baek, and Y. Yoon. 2004. Improved recombinant gene expression in CHO cells using matrix attachment regions. J. Biotechnol. 107: 95-105 DOI ScienceOn |
21 | Mohanraj, D., T. Olson, and S. Ramakrishnan. 1995. Expression of biologically active human vascular endothelial growth factor in yeast. Growth Factors 12: 17-27 DOI ScienceOn |
22 | Tammela, T., B. Enholm, K. Alitalo, and K. Paavonen. 2005. The biology of vascular endothelial growth factors. Cardiovasc. Res. 65: 550-563 DOI ScienceOn |
23 | Ferrara, N. 2002. Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: Therapeutic implication. Semin. Oncol. 29: 10-14 |
24 | Folkman, J. 1995. Angiogenesis in cancer, vascular, rheumatoid and other diseases. Nat. Med. 1: 27-31 DOI ScienceOn |
25 | Yamazaki, Y. and T. Morita. 2006. Molecular and functional diversity of vascular endothelial factors. Mol. Divers. 10: 515-527 DOI ScienceOn |
26 | Na, K. H., S. C. Kim, K. S. Seo, S. H. Lee, W. B. Kim, and K. C. Lee. 2005. Purification and characterization of recombinant human follicle stimulating hormone produced by Chinese hamster ovary cells. J. Microbiol. Biotechnol. 15: 395-402 과학기술학회마을 |
27 | Kastrup, J., E. Jorgensen, A. Ruck, K. Tagil, D. Glogar, W. Ruzyllo, H. E. Botker, D. Dudek, V. Drvota, B. Hesse, L. Thuesen, P. Blomberg, M. Gyongyosi, C. Sylven; Euroinject One Group. 2005. Direct intramyocardial plasmid vascular endothelial growth factor-A165 gene therapy in patient with stable severe angina pectoris. J. Am. Coll. Cardiol. 45: 982-988 DOI ScienceOn |
28 | Conn, G., D. D. Soderman, M. T. Schaeffer, M. Wile, V. B. Hatcher, and K. A. Thomas. 1990. Purification of glycoprotein vascular endothelial cell mitogen from rat glioma-derived cell line. Proc. Natl. Acad. Sci. USA 87: 1323-1327 |