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Genetic and Antigenic Characterization of Swine H1N2 Influenza Viruses Isolated from Korean Pigs  

Jo, Su-Kyoung (Laboratory o/Influenza Research, College of Veterinary Medicine, Chungnam National University)
Kim, Hyun-Soo (Laboratory o/Influenza Research, College of Veterinary Medicine, Chungnam National University)
Cho, Sung-Whan (Laboratory o/Influenza Research, College of Veterinary Medicine, Chungnam National University)
Seo, Sang-Heui (Laboratory o/Influenza Research, College of Veterinary Medicine, Chungnam National University)
Publication Information
Journal of Microbiology and Biotechnology / v.17, no.5, 2007 , pp. 868-872 More about this Journal
Abstract
H1N2 influenza viruses are circulating in pigs worldwide and cause considerable economic losses to the pig industry. We genetically analyzed the genes of our isolates from Korean pigs, and compared the antigenicity of our isolates with swine H1N2 viruses isolated from pigs in the U.S.A. In addition, we serologically surveyed the infection rate of swine H1N2 viruses in pigs. We found that H1N2 isolates from Korean pigs are genetically more related to swine H1N2 viruses isolated from pigs in the U.S.A. than those in European countries. When antigenicity was compared, our isolates were weakly reacted to antibodies against swine H1N2 viruses isolated from pigs in the U.S.A. The serological surveillance using sera from pigs in Korea showed that about 46% was positive for H1N2 viruses. Our results suggest that swine H1N2 viruses are widespread in Korean pigs, and the development of a vaccine against H1N2 viruses may help to control their infection in pigs.
Keywords
Influenza virus; swine; H1N2; pigs; serology; antigenicity;
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