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Redoxcitrinin, a Biogenetic Precursor of Citrinin from Marine Isolate of Fungus Penicillium sp.  

Zhang, Dahai (College of Chemistry & Chemical Engineering, Ocean University of China)
Li, Xianguo (College of Chemistry & Chemical Engineering, Ocean University of China)
Kang, Jung-Sook (College of Dentistry, Pusan National University)
Choi, Hong-Dae (Department of Chemistry, Dongeui University)
Jung, Jee-H. (College of Pharmacy, Pusan National University)
Son, Byeng-Wha (Department of Chemistry, Pukyong National University)
Publication Information
Journal of Microbiology and Biotechnology / v.17, no.5, 2007 , pp. 865-867 More about this Journal
Abstract
A chemical analysis of the fermentation of the marine-derived fungus Penicillium sp. led to the isolation of a biogenetic precursor of citrinin, redoxcitrinin(1), together with polyketide mycotoxins, phenol A(2), citrinin H2(3), 4-hydroxymellein(4), citrinin(5), and phenol A acid(6). The structures of compounds 1-6 were determined on the basis of physicochemical data analyses. Among them, compounds 1-3 exhibited a potent radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl(DPPH) with $IC_{50}$ values of 27.7, 23.4, and $27.2{\mu}M$, respectively.
Keywords
Marine-derived fungus; Penicillium sp.; redoxcitrinin; biogenetic precursor; citrinin; polyketide;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
Times Cited By Web Of Science : 5  (Related Records In Web of Science)
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