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Heterogeneous rRNA Molecules Encoded by Streptomyces coelicolor M145 Genome are All Expressed and Assembled into Ribosomes  

Kim, Hyun-Lee (Graduate School of Life Science and Biotechnology, Pochon CHA University)
Shin, Eun-Kyoung (Department of Life Science, Chung-Ang University)
Kim, Hong-Man (Department of Life Science, Chung-Ang University)
Go, Ha-Young (Department of Life Science, Chung-Ang University)
Roh, Jae-Sook (Department of Pharmacological Research, National Institute of Toxicological Research)
Bae, Jee-Hyeon (Graduate School of Life Science and Biotechnology, Pochon CHA University)
Lee, Kang-Seok (Department of Life Science, Chung-Ang University)
Publication Information
Journal of Microbiology and Biotechnology / v.17, no.10, 2007 , pp. 1708-1711 More about this Journal
Abstract
The Streptomyces coelicolor M145 genome harbors six copies of divergent rRNA operons that differ at ${\sim}0.2%$ and ${\sim}0.6%$ of the nucleotide positions in small subunit (SSU) and large subunit (LSD) rRNA genes, respectively. When these rRNA genes are expressed, a single cell may harbor three different kinds of SSU rRNA and five kinds of LSU rRNA. Primer extension analyses revealed that all of the heterogeneous rRNA molecules are expressed and assembled into ribosomes. This finding and the maintenance of the intragenomic variability of rRNA operons imply the existence of functional divergence of rRNA species in this developmentally complex microorgamsm.
Keywords
Streptomyces coelicolor; rRNA genes; SSU rRNA; LSU rRNA; heterogeneous rRNA;
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Times Cited By KSCI : 5  (Citation Analysis)
Times Cited By Web Of Science : 4  (Related Records In Web of Science)
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