Differential Gene Expression in Estradiol-3-Benzoate-Treated Liver and Chemically- Induced Hepatocellular Carcinoma
![]() |
KIM , SEYL
(Department of Pathology, National Institute of Toxicology Research, Laboratory of Molecular Biology, School of Life Sciences and Biotechnology, Korea University)
KANG, JIN-SEOK (Department of Pathology, National Institute of Toxicology Research) JANG, DONG-DEUK (Department of Pathology, National Institute of Toxicology Research) LEE, KOOK-KYUNG (Department of Veterinary Medicine, Cheju National University) KIM, SOON-AE (Department of Pharmacology, Eulji University School of Medicine) HAN, BEOM-SEOK (Department of Pathology, National Institute of Toxicology Research) PARK, YOUNG-IN (Laboratory of Molecular Biology, School of Life Sciences and Biotechnology, Korea University) |
1 | Fillit, H., H. Weinreb, I. Cholst, V. Luine, B. McEwen, R. Amador, and J. Zabriskie. 1986. Observations in a preliminary open trial of estradiol therapy for senile dementia-Alzheimer’s type. Psychoneuroendocrinology 11: 337-345 |
2 | La Vecchia, C., E. Negri, L. Cavalieri d’Oro, and S. Franceschi. 1998. Liver cirrhosis and the risk of primary liver cancer. Eur. J. Cancer Prev. 7: 315-320 |
3 | Matsuura, B., Y. Taniguchi, and Y. Ohta. 1994. Effect of antiandrogen treatment on chemical hepatocarcinogenesis in rats. J. Hepatol. 21: 187-193 |
4 | Sylvia, V. L., T. Hughes, D. D. Dean, B. D. Boyan, and Z. Schwartz. 1998. 17beta-estradiol regulation of protein kinase C activity in chondrocytes is sex-dependent and involves nongenomic mechanisms. J. Cell Physiol. 176:435-444 DOI ScienceOn |
5 | Xu, J. W., J. Gong, X. M. Chang, J. Y. Luo, L. Dong, Z. M. Hao, A. Jia, and G. P. Xu. 2002. Estrogen reduces CCL4-induced liver fibrosis in rats. World J. Gastroenterol. 8: 883-887 |
6 | Kemp, C. J. and N. R. Drinkwater. 1989. Genetic variation in liver tumor susceptibility, plasma testosterone levels, and androgen receptor binding in six inbred strains of mice. Cancer Res. 49: 5044-5047 |
7 | Cai, L., C. J. Wang, Z. L. Xu, D. X. Deng, S. Chakrabarti, and M. G. Cherian. 1998. Metallothionein and apoptosis in primary human hepatocellular carcinoma from northern China. Anticancer Res. 18: 4667-4672 |
8 | Dang, Z. C., R. L. van Bezooijen, M. Karperien, S. E. Papapoulos, and C. W. Lowik. 2002. Exposure of KS483 cells to estrogen enhances osteogenesis and inhibits adipogenesis. J. Bone Miner. Res. 17: 394-405 |
9 | Paassilta, M., A. Karjalainen, K. Kervinen, M. J. Savolainen, J. Heikkinen, A. C. Backstrom, and Y. A. Kesaniemi. 2000. Insulin-like growth factor binding protein-1 (IGFBP-1) and IGF-I during oral and transdermal estrogen replacement therapy: Relation to lipoprotein(a) levels. Atherosclerosis 149: 157-162 |
10 | Stefan, C., W. Stalmans, and M. Bollen. 1996. Threonine autophosphorylation and nucleotidylation of the hepatic membrane protein PC-1. Eur. J. Biochem. 241: 338-342 |
11 | Choi, J. Y., M. Kim, and J. H. Lee. 2002. Reevaluation of the change of leuconostoc species and Lactobacillus plantarum by PCR during kimchi fermentation. J. Microbiol. Biotechnol. 12: 166-171 |
12 | Jeoung, D., J. H. Kim, Y. H. Lee, M. Baek, S. Lee, N. I. Baek, and H. Y. Kim. 2002. cDNA microarray analysis of transcriptional response to hyperin in human gastric cancer cells. J. Microbiol. Biotechnol. 12: 664-668 |
13 | Segars, J. H. and P. H. Driggers. 2002. Estrogen action and cytoplasmic signaling cascades. Part I: Membraneassociated signaling complexes. Trends Endocrinol. Metab. 13: 349-354 |
14 | Shimizu, I., M. Yasuda, Y. Mizobuchi, Y. R. Ma, F. Liu, M. Shiba, T. Horie, and S. Ito. 1998. Suppressive effect of oestradiol on chemical hepatocarcinogenesis in rats. Gut 42: 112-119 |
15 | Ramirez, V. D. and J. Zheng. 1996. Membrane sex-steroid receptors in the brain. Front. Neuroendocrinol. 17: 402- 439 |
16 | Cicchetti, P., A. J. Ridley, Y. Zheng, R. A. Cerione, and D. Baltimore. 1995. 3BP-1, an SH3 domain binding protein, has GAP activity for Rac and inhibits growth factor-induced membrane ruffling in fibroblasts. EMBO J. 14: 3127-3135 |
17 | Deng, D. X., S. Chakrabarti, M. P. Waalkes, and M. G. Cherian. 1998. Metallothionein and apoptosis in primary human hepatocellular carcinoma and metastatic carcinoma. Histopathology 32: 348-355 |
18 | Lin, X., P. Nelson, and I. H. Gelman. 2000. SSeCKS, a major protein kinase C substrate with tumor suppressor activity, regulates G13S progression by controlling the expression and cellular compartmentalization of cyclin D. Mol. Cell. Biology 20: 7259-7272 DOI ScienceOn |
19 | Sawaki, M., K. Enomoto, H. Takahashi, Y. Nakajima, and M. Mori. 1990. Phenotype of preneoplastic and neoplastic liver lesions during spontaneous liver carcinogenesis of LEC rats. Carcinogenesis 11: 1857-1861 |
20 | Weber, G. F., R. T. Bronson, J. Ilagan, H. Cantor, R. Schmits, and T. W. Mak. 2002. Absence of the CD44 gene prevents sarcoma metastasis. Cancer Res. 62: 2281-2286 |
21 | Yue, S. Q., Y. L. Yang, K. F. Dou, and K. Z. Li. 2003. Expression of PCNA and CD44 mRNA in colorectal cancer with venous invasion and its relationship to liver metastasis. World J. Gastroenterol. 9: 2863-2865 |
22 | Colditz, G. A., K. M. Egan, and M. J. Stampfer. 1993. Hormone replacement therapy and risk of breast cancer: Results from epidemiologic studies. Am. J. Obstet. Gynecol. 168: 1473-1480 |
23 | Even, C., G. Launoy, T. Collet, O. Duval, M. A. Piquet, A. Rougereau, J. C. Verwaerde, and T. Dao. 1997. Epidemiology of hepatocellular carcinoma in the department of Calvados. Gastroenterol. Clin. Biol. 21: 450-458 |
24 | Horwitz, K. B., Y. Koseki, and W. L. McGuire. 1978. Estrogen control of progesterone receptor in human breast cancer: Role of estradiol and antiestrogen. Endocrinology 103: 1742-1751 |
25 | Watson, P. H., L. J. Fraher, G. N. Hendy, U. I. Chung, M. Kisiel, B. V. Natale, and A. B. Hodsman. 2000. Nuclear localization of the type 1 PTH/PTHrP receptor in rat tissues. J. Bone Miner. Res. 15: 1033-1044 |
26 | Pizzuti, A., L. Frittitta, A. Argiolas, R. Baratta, I. D. Goldfine, M. Bozzali, T. Ercolino, G. Scarlato, L. Iacoviello, R. Vigneri, V. Tassi, and V. Trischitta. 1999. A polymorphism (K121Q) of the human glycoprotein PC-1 gene coding region is strongly associated with insulin resistance. Diabetes 48: 1881-1884 |
27 | Yu, M. C., J. M. Yuan, S. Govindarajan, and R. Ross. 2000. Epidemiology of hepatocellular carcinoma. Can. J. Gastroenterol. 14: 703-709 |
28 | Roder, K., K. H. Kim, and H. S. Sul. 2002. Induction of murine H-rev107 gene expression by growth arrest and histone acetylation: Involvement of an Sp1/Sp3-binding GCboxq. Biochem. Biophys. Res. Commun. 294: 63-70 |
29 | Erdstein, J., S. Wisebord, S. Y. Mishkin, and S. Mishkin. 1989. The effect of several sex steroid hormones on the growth rate of three Morris hepatoma tumor lines. Hepatology 9: 621-624 |
30 | Nelson, P. and I. H. Gelman. 1997. Cell-cycle regulated expression and serine phosphorylation of the myristylated protein kinase C substrate, SSeCKS: Correlation with cell confluency, G0 phase and serum response. Mol. Cell. Biochem. 175: 233-241 |
31 | Turner, R. T., B. L. Riggs, and T. C. Spelsberg. 1994. Skeletal effects of estrogen. Endocr. Rev. 15: 275-300 |
32 | Henderson, B. E., R. K. Ross, A. Paganini-Hill, and T. M. Mack. 1986. Estrogen use and cardiovascular disease. Am. J. Obstet. Gynecol. 154: 1181-1186 |
33 | Hoe, H. S., I. G. Jo, H. J. Shin, H. J. Jeon, H. K. Kim, J. S. Lee, Y. S. Kim, D. S. Lee, and S. T. Kwon. 2003. Cloning and expression of the gene for inorganic pyrophosphatase of Thermus caldophilus GK24 and properties of the enzyme. J. Microbiol. Biotechnol. 13: 139-145 |
34 | Mishkin, S. Y., E. Farber, R. K. Ho, S. Mulay, and S. Mishkin. 1983. Evidence for the hormone dependency of hepatic hyperplastic nodules: Inhibition of malignant transformation after exogenous 17 beta-estradiol and tamoxifen. Hepatology 3: 308-316 |
35 | Mackay, A., C. Jones, T. Dexter, R. L. Silva, K. Bulmer, A. Jones, P. Simpson, R. A. Harris, P. S. Jat, A. M. Neville, L. F. Reis, S. R. Lakhani, and M. J. O’Hare. 2003. cDNA microarray analysis of genes associated with ERBB2 (HER2/neu) overexpression in human mammary luminal epithelial cells. Oncogene 22: 2680-2688 |
![]() |