Enhancement of Erythropoietin Production from Chinese Hamster Ovary(CHO) Cells by Introduction of the Urea Cycle Enzymes, Carbamoyl Phosphate Synthetase I and Ornithine Transcarbamylase |
Kim, Na-Young
(College of Pharmacy, Chung Ang University)
Lee, Yun-Jeong (College of Pharmacy, Chung Ang University) Kim, Hyung-Jin (College of Pharmacy, Chung Ang University) Choi, Jung-Ho (College of Pharmacy, Chung Ang University) Kim, Jung-Kwon (College of Pharmacy, Chung Ang University) Chang, Kern-Hee (Samsung Fine Chemicals Co., LTD. R&D Center) Kim, Jung-Hoe (Department of Biological Science, KAIST) Kim, Hong-Jin (College of Pharmacy, Chung Ang University) |
1 |
Growth behavior of Chinese hamster ovary cells in a compact loop bioreactor. 2. Effects of medium components and waste products
/
DOI ScienceOn |
2 |
Effect of ammonia on endocytosis, cytokine production and lysosomal enzyme activity of a microglial cell line
/
DOI ScienceOn |
3 |
Development of strategies of the removal of ammonia from animal cell cultures
/
|
4 |
Beyound erythropoiesis: Novel applications for recombinant human erythropoietin
/
DOI ScienceOn |
5 |
Ammonia removal using hepatoma cells in mammalian cell cultures
/
DOI ScienceOn |
6 |
Effect of sodium butyrate on glycosylation of recombinant erythropoietin
/
|
7 |
Methods for reducing the ammonia in hybridoma cell cultures
/
DOI ScienceOn |
8 |
The effect of ammonia on the O-linked glycosylation of granulocyte colony-stimulating factor produced by Chinese hamster ovary cell
/
DOI ScienceOn |
9 |
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding
/
DOI ScienceOn |
10 |
The effects of glutamine utilization and ammonia production on the growth of BHK cells in microcarrier culture
/
DOI ScienceOn |
11 |
Reduction of ammonia accumulation and improvement of cell viability by expression of urea cycle enzymes in Chinese Hamster Ovary cells
/
|
12 |
Effects of ammonia and lactate on growth, metabolism, and productivity of BHK cells
/
DOI ScienceOn |
13 |
Management of the hematologic manifestations of HIV disease
/
DOI ScienceOn |
14 |
Chromatographic separation of recombinant human erythropoietin isoforms
/
|
15 |
The oligosaccharides of glycoproteins: Bioprocess factors affecting oligosaccharide structure and their effect on glycoprotein properties
/
DOI ScienceOn |
16 |
Transient responses of hybridoma cells in continuous culture to step changes in amino acids and vitamin concentrations
/
DOI ScienceOn |
17 |
The role of cabohydrate in recombinant human erythropoietin
/
DOI ScienceOn |
18 |
Evidence that monoclonal antibody production kinetics is related to the integral of viable cells in batch systems
/
DOI |
19 |
The importance of ammonia in mammalian cell cultures
/
DOI ScienceOn |
20 |
Structures and functional roles of the sugar chains of human erythropoietins
/
DOI ScienceOn |
21 |
A rapid assay method for ammonia using glutamine synthetase from glutamateproducing bacteria
/
DOI ScienceOn |
22 |
Erythropoietin production from CHO cell grown by continuous cultue in a fluidized-bed bioreactor
/
DOI ScienceOn |
23 |
Fully automated roller bottle handling system for large-scale culture of mammalian cells
/
DOI ScienceOn |
24 |
Influence of ammonium on growth, metabolism, and productivity of a continuous suspension Chinese hamster ovary cell culture
/
DOI ScienceOn |
25 |
Expression of recombinant cytoplasmic yeast pyruvatecarboxylase for the improvement of the production of human erythropoietin by recombinant BHK-21 cells
/
DOI ScienceOn |
26 |
Separation methods for glycoprotein analysis and preparation
/
DOI |
27 |
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
/
DOI ScienceOn |
28 |
Development of a serum free medium for the production of erythropoietin by suspension culture of recombinant CHO cells using a statistical design
/
DOI |
29 |
Catabolic control of hybridoma cells by glucose and glutamine limited fed batch cultures
/
DOI ScienceOn |
30 |
Pathogenesis of the anemia of chronic disease: A cytokine-mediated anemia
/
DOI ScienceOn |
31 |
Effects of ammonia and lactate on hybridoma growth, metabolism, and antibody production
/
DOI |
32 |
Expression of carbamoyl phosphate synthetase I and ornithine transcarbamoylase genes in Chinese hamster ovary dhfr-cells decreases accumulation of ammonium ion in culture media
/
DOI ScienceOn |
33 |
Efficiency of promoter and cell line in high-level expression of erythropoietin
/
DOI ScienceOn |
34 |
Glycobiology
/
DOI ScienceOn |
35 |
The importance of N-and O-linked oligosaccharides for the biosynthesis and in vitro and in vivo biologic activities of erythropoietin
/
|
36 |
Effects of ammonia on CHO cell growth, erythropoietin production, and glycosylation
/
DOI ScienceOn |
37 |
Effects of ammonia and glucosamine on the heterogeneity of erythropoietin glycoforms
/
DOI ScienceOn |
38 |
Evaluation of phenylboronate agarose for indusrial-scale purification of erythropoietin from mammalian cell cultures
/
DOI ScienceOn |
39 |
Role of nucleotide sugar pools in the inhibition of NCAM polysialylation by ammonia
/
DOI ScienceOn |