High-Level Expression of Recombinant Human Interleukin-2 in Chinese Hamster Ovary Cells Using the Expression System Containing Transcription Terminator
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Kim, Eun-Ju
(Graduate School of Biotechnology, Kyung Hee University)
Kim, Dong-Jun (Graduate School of Biotechnology, Kyung Hee University) Hwang, Hye-Yeon (PanGen Biotech Lab. Inc.) Yoon, Jae-Seung (Graduate School of Biotechnology, Kyung Hee University) Yoon, Ye-Up (Mogam Biotechnology Research Institute) Baek, Kwang-Hee (Graduate School of Biotechnology, Kyung Hee University) |
1 |
Molecular cloning of human interleukin 2 cDNA and its expression in E. coli
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DOI ScienceOn |
2 |
Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators
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DOI |
3 |
Augmentation of the anti-tumor therapeutic efficacy of long-term cultured T lymphocytes by in vivo administration of purified interleukin 2
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DOI ScienceOn |
4 |
AU binding proteins recruit the exosome to degrade ARE-containing mNAs
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DOI ScienceOn |
5 |
Screening of high-porductivity cell lines and investigation of their physiology in Chinese hamster ovary (CHO) cell cultures for transforming growth factor-<TEX>${\beta}$</TEX> production
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6 |
Deletion analysis of the Chinese hamster dihydrofolate reductase ene promoter
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7 |
Structures of the major carbohydrates of natural human interleukin-2
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DOI ScienceOn |
8 |
Interleukin 2 dependence of human natural killer (NK) cell activity
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9 |
Regulation of the production of immune interferon and cytotoxic T lymphocytes by interleukin 2
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10 |
Characterization of recombinant glycosylated human interleukin 2 produced by a recombinant plasmid transformed CHO cell line
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DOI ScienceOn |
11 |
Characterization of human interleukin 2 derived from Escherichia coli
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DOI |
12 |
Amino acid squence and posttranslational modification of human interleukin 2
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DOI ScienceOn |
13 |
Biological activity of recombinant human interleukin-2 produced in Escherichia coli
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DOI |
14 |
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15 |
Site-specific mutagenesis of the human interleukin-2 gene: Structure-function analysis of the cysteine residues
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DOI |
16 |
Structure and expression of a cloned cDNA for human interleukin-2
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DOI ScienceOn |
17 |
Improved mammalian expression systems by manipulating trancriptional temination regions
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DOI ScienceOn |
18 |
RNA polymerase Ⅱ transcription terminates at a specific DNA sequence in a HeLa cell-free reaction
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DOI ScienceOn |
19 |
Interleukin-2 carbohydrate recognition modulates CTLL-2 cell proliferation
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DOI ScienceOn |
20 |
Lymphokine-activated killer cell phenomenon. Lysis of naturalkill-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes
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DOI ScienceOn |
21 |
Improved recombinant gene expression in CHO cells using matrix attachment regions
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DOI ScienceOn |
22 |
Characterization of humanized antibody produced by apoptosis-resistant CHO cells under sodium bytyrate-induced condition
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23 |
Compilation and anlysis of sequences upstream from the translational start site in eukaryotic mRNAs
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24 |
Separation by cation-exchange high-performance liquid chromatography of three forms of Chinese hamster ovary cell-derived recombinant human interleukin-2
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DOI |
25 |
Selective in vitro growth of T lymphocytes from normal human bone marrows
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DOI |
26 |
The expanding universe of T-cell subsets: Th1, Th2 and more
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DOI ScienceOn |
27 |
Adoptive immunotherapy of established pulmonary metastases with LAK cells and recombinant interleukin-2
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DOI |
28 |
Comparison of the biological properties of purified natural and recombinant human interleukin-2
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DOI ScienceOn |
29 |
Expession of amplified cDNA and genomic sequnces encoding human interleukin 2 in Chinese hamster ovary cells
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DOI |
30 |
Relative cloning efficiencies and long-term propagation capacity for T cell clones of highly purified natual interleukin 2 compared to recombinant interleukin 2 in man
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DOI |
31 |
Transcription interference and termination between duplicated <TEX>${\alpha}$</TEX>-globin gene constructs suggests a novel mechanism for gene regulation
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DOI ScienceOn |
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