Premature Release of Polyketide Intermediates by Hybrid Polyketide Synthase in Amycolatopsis mediterranei S699 |
Hong, Jay-Sung-Joong
(Interdisciplinary Program of Biochemical Engineering and Biotechnology, Seoul National University)
Choi, Cha-Yong (Interdisciplinary Program of Biochemical Engineering and Biotechnology, Seoul National University, School of Chemical Engineering, College of Engineering, Seoul National University) Yoo, Yeo-Joon (School of Chemical Engineering and Bioengineering, University of Ulsan) |
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Intermediates of rifamycin polyketide synthase produced by an Amycolatopsis mediterranei mutant with inactivated rifF gene
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In vitro activity of new rifamycins against rifampicin-resistant M. tuberculosis and MAIS complex mycobacteria
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DOI |
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Thioesterase and the premature termination of polyketide chain elongation in rifamycin B biosynthesis by Amycolatopsis mediterranei S699
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DOI ScienceOn |
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Polyketide antibiotics produced by type-I multifunctional enzymes:rifamycins
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Rifamycin, a new antibiotic:Preliminary report. Farmaco. Ed.
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Chemistry of the ansamycin antibiotics
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Harnessing the biosynthetic potential of mocular polyketide synthase
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DOI ScienceOn |
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Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel unnatural natural products
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DOI ScienceOn |
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Characterization of the enzymatic domains on the modular polyketide synthase involved in rifamycin B biosynthesis by Amycolatopsis metiterrenei
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Identification of Streptomyces sp. producing new polyene antibiotics and in vivo antimicrobial activity of Tetrin C against phytopathogenic fungi
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과학기술학회마을 |
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Generation of multiple bioactive macrolides by hybrid modular polyketide synthases in Streptomyces venezuelae
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DOI ScienceOn |
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The crisis in antibiotic research
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Manipulation of modular polyketide synthases
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An erythromycin derivative produced by targeted gene disruption in Saccharopolyspora erythraea
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RNA polymerase-rifamycin. A molecular model of inhibition
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A new analog of antimycin from streptomyces sp. MO3033
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과학기술학회마을 |
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On the constitution and configuration of rifamycins B, O, S and SV.
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A genetic approach to the biosynthesis of the rifamycin chromophore in Nocardia mediterranei. Ⅲ. Isolation and idenification of 3-amino-5-hydroxybenzoic acid as a direct precursor of the seven carbon amino starter-unit
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Formation of functional heterologous complexes using subunits from the picromycin, erythromycin and oleandomycin polyketide synthase
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DOI ScienceOn |
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Biosynthesis of the ansamycin antibiotic rifamycin:Deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis Mediterranei S699
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DOI ScienceOn |
21 |
Combinatorial biosynthesis for new drug discovery
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In vitro susceptibility of Mycobacterium avium complex and Mycobacterium tuberculosis strains to a spiropiperidyl rifamycin
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Direct evidence that the rifamycin polyketide synthase assembles polyketide chains processively
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DOI ScienceOn |
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Reviving the antibiotic miracle
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Tuberculosis in the AIDS era.
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