Reduction of Ammonia Accumulation and Improvement of Cell Viability by Expression of Urea Cycle Enzymes in Chinese Hamster Ovary Cells |
Chung, Myung-Il
(College of Pharmacy, Chung Ang University)
Lim, Mi-Hee (College of Pharmacy, Chung Ang University) Lee, Yun-Jeong (College of Pharmacy, Chung Ang University) Kim, Ik-Hwan (Graduate School of Biotechnology, Korea University) Kim, Ick-Young (Graduate School of Biotechnology, Korea University) Kim, Jung-Hoe (Department of Biological Sciences, KAIST) Chang, Kern-Hee (Samsung Fine Chemicals Co., LTD. R&D Center) Kim, Hong-Jin (College of Pharmacy, Chung Ang University) |
1 |
Ammonia effects in culture of normal and transformed 3T3 cells
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High yields from microcarrier cultures by medium perfusion
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3 |
Effect of sodium butyrate on glycosylation of recombinant erythropoietin
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과학기술학회마을 |
4 |
Effects of ammonia and lactate on growth, metabolism, and productrivity of BHK cells
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DOI ScienceOn |
5 |
Complete nucleotide sequence of cDNA and deduced amino acid sequence of rat liver arginase
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6 |
Role of nucleotide sugar pools in the inhibition of NCAM polysialylation by ammonia
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DOI ScienceOn |
7 |
Development of strategies for the removal of ammonia from animal cell cultures
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8 |
Adaptation to nonammoniagenic medium and selective substrate feeding lead to enhanced yields in animal cell culture
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9 |
Chloroquine and ammonium chloride prevents teminal glycosylation of immunoglobulins in plasma cells without affecting secretion
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DOI ScienceOn |
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11 |
Expression of carbamoyl phosphate synthetase I and ornithine transcarbamoylase genes in Chinese hamster ovary dhfr-cells decreases accumulation of ammonium ion in culture media
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12 |
Effect of ammonia on endocytosis, cytokine production and lysosomal enzyme activity of a microglial cell line
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DOI ScienceOn |
13 |
The effects of glutamine utilization and ammonia production on the growth of BHK cells in microcattier culture
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DOI ScienceOn |
14 |
Integrated detoxification: Reduction of ammonium concentration by dialysis with cation exchange membranes
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15 |
Ammonium ion effects and its in situ removal by using immobilized adsorbent in hybridoma cell culture
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과학기술학회마을 |
16 |
Reduction of waste product excretion via nutrient control: Possible strategies for maximizing product and cell yields on serum in cultures of mammalian cells
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DOI ScienceOn |
17 |
Lobular patterns of expression and enzyme activities of glutamine synthase, carbamoylphosphate development of the porcine liver
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DOI ScienceOn |
18 |
Influence of ammonium on growth, metabolism, and productivity of a continuous suspension Chinese hamster ovary cell culture
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DOI ScienceOn |
19 |
Effect of ammonium ion and extracellular pH on hybridoma cell metabolism and antibody production
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DOI |
20 |
Ammonium ion transport by the Na+K+2Cl cotransporter induces apoptosis in hyvridoma cells
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DOI ScienceOn |
21 |
Growth behavior of Chinese hamster ovary cells in a compact loop bioreactor, 2. Effects of medium components and waster products
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DOI ScienceOn |
22 |
Characteristics of ammonia removal in biofilters inoculated with earthworm cast
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과학기술학회마을 |
23 |
Effects on cell proliferation of metabolites produced by cultured cells and their removal from culture in defined media
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24 |
Effects of ammonia on CHO cell growth, erythropoietin production, and glycosylation
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DOI ScienceOn |
25 |
The effect of ammonia on the O-linked glycosylationof granulocyte colony-stimulating factor produced by Chinese Hamster ovary cell
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DOI ScienceOn |
26 |
Molecular clonig of cDNA for rat argininosuccinate lyase and its expression in rat hepatoma cell lines
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27 |
Effects of ammonia and lactate on hybridoma growth, metabolism, and antibody production
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DOI |
28 |
Transient responses of hybridoma cells in continuous culture to step changes in amino acids and vitamin concentrations
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DOI ScienceOn |
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30 |
Expression patterns of mRNAs for ammonia-metablizing enzymes in the developing rat: The ontogenesis of hepatocyte heterogeneity
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DOI ScienceOn |
31 |
Development of the ornithine cycle in rat liver: Zonation of a metabolic parhway
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DOI ScienceOn |
32 |
HBs-Mab production in perfusion culture with selective ammonia removal system
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DOI ScienceOn |
33 |
Ammonia toxicity for mammalian and avian lymphosytes from blood
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DOI ScienceOn |
34 |
Cell death in bioreactors: A role for apoptosis
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DOI ScienceOn |
35 |
The control of ammonia toxicity in large scale culture of C 127 cells and hybridomas
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36 |
Methods for reducing the amrnonia in hybridoma cell cultures
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DOI ScienceOn |
37 |
Catabolic control of hybridoma cells by glucose and glutamine linited fed batch cultures
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DOI ScienceOn |
38 |
Ammonium affects the glycosylation patterns of recombinant mouse placement lactogen- I by Chinese hamster ovary cells in a pH-dependent manner
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DOI ScienceOn |
39 |
Ammonia removal from mammalian cell culture medium by ion-exchange membranes
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