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Two Neuroprotective Compounds from Mushroom Daldinia concentrica

Lee, In-Kyoung (Korea Research Institute of Bioscience and Biotechnology)
Bong-Sik Yun (Korea Research Institute of Bioscience and Biotechnology)
Young-Ho Kim (College of Pharmacy, Chungnam National University)
Ick-Dong Yoo (Korea Research Institute of Bioscience and Biotechnology)

Publication Information

Journal of Microbiology and Biotechnology / v.12, no.4, 2002 , pp. 691-691 More about this Journal

Abstract

In the course of our screening for neuroprotective agents, a new compound (1) was isolated together with a known compound, caruilignan C (2), from the fruiting body of Daldinia concentrica. Their structures were determined on the basis of various spectral studies. Both compounds exhibited neuroprotective effect against iron-induced neurodegeneration in a primary culture of mouse cortical neurons.

Keywords

Neuroprotective compound; mushroom; Daldinia concentrica;

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