Browse > Article

The Hepatoprotective Effects of Polysaccharides Isolated from Submerged Fermentation of Ganoderma lucidum  

Zhang, Xue-Hong (College of Life Science and Biotechnology, Shanghai Jiaotong University)
Hu, Hong-Bo (College of Life Science and Biotechnology, Shanghai Jiaotong University)
Tang, Yong-Lian (College of Life Science and Biotechnology, Shanghai Jiaotong University)
Huang, Rui-Shan (College of Life Science and Biotechnology, Shanghai Jiaotong University)
Luo, Jiu-Fu (College of Life Science and Biotechnology, Shanghai Jiaotong University)
Publication Information
Journal of Microbiology and Biotechnology / v.12, no.3, 2002 , pp. 367-370 More about this Journal
Abstract
A neutral polysaccharide, GP, was isolated from a fermentation broth of Ganoderma lucidum Acid hydrolysis and a paper chromatography analysis indicated that the polysacchride was composed of glucose, xylose, and mannose. The molecular weight was estimated to be $2.9{\times}10^4$. The oral administration of GP to mice showed that it can inhibit liver damage induced by GalN and $CCl_4$.
Keywords
Neutral polysaccharide GP; Ganoderma lucidum; acid hydrolysis; paper chromatography; oral administration;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
Times Cited By Web Of Science : 9  (Related Records In Web of Science)
연도 인용수 순위
1 Reishi, Ganoderma lucidum and Ganodermatsugae: Bioactive substances and medicinal effects /
[ Mizuno, T.;G. Wang;J. Zhang;H. Kawagishi;T. Nishitoba;J. Li ] / Food Reviews International   DOI   ScienceOn
2 Hepatoprotective effect of extracellular polymer produced by submerged culture of GLWK-003 /
[ Song, H. C.;B. K. Yang;K. S. Ra;D. H. Shon;E. J. Park;G. I. Go;Y. H. Kim ] / J. Microbiol. Biotechnol.   과학기술학회마을
3 Fractionation and antitumor activity of the water soluble exopolysaccharide by submerged cultivation of Ganoderma lucidum mycelium /
[ Lee, S. Y.;T. S. Kang;S. O. Moon;I. D. Lew;M. Y. Lee ] / Kor. J. Appl. Microbiol. Biotechnol.
4 Medicinal benefits of mushroom Ganoderma /
[ Jong, S. C.;J. M. Birmingham ] / Adv. Appl. Microbiol.   DOI
5 The influence of environmental conditions on polysaccharide formation by Ganoderma lucidum in submerged cultures /
[ Yang, F. C.;C. B. Liau ] / Process Biochem.   DOI
6 Effects of acetylbergenin against D-galactosamine-induced hepatotoxicity in rats /
[ Lim, H. K.;H. S. Kim;H. S. Choi;S. W. Oh;C. G. Jang ] / Pharm. Res.   DOI   ScienceOn
7 Study on Ganoderma lucidum I. Liquid culture and chemical composition of mycelium /
[ Tseng, T. C.;M. S. Shiao;Y. S. Shieh;Y. Y. Hao ] / Biotanical Bull. Academia Sinica.
8 Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction /
[ Ohkawa, H.;N. Ohishi;K. Yagi ] / Anal. Biochem.   DOI   ScienceOn
9 Structure and antitumor activities of the polysaccharide isolated from fruiting body and the growing culture of mycelium of Ganoderma lucidum /
[ Sone, Y.;R. Okura;N. Wada;E. Kishida;A. Misaki ] / Agr. Biolog. Chem.   DOI
10 Colorimetric method for determination of sugers and related substances /
[ Dubois, M.;K.A. Gilles;J.K. Hamilton;P.A. Roberts;F. Smith ] / Anal. Cham.   DOI
11 Studies on extraction and structure of the polysaccharide from Ganoderma lucidum strain GL 8801 by liquid fermentation /
[ Lin, Y. H. ] / J. Fuzhou Univ.
12 Effects of geraniin of the liver in rats Ⅲ - cirrelation berween lipid accumulation and liver damage in CCI₄-treated rats /
[ Yuka, N.;O. Takuo;A. Hiroko ] / Nat. Med.
13 Purification and its biological activities of exo-polysaccharide of Ganoderma lucidum /
[ Li, P. Z.;K. Q. Zhang ] / Acta Microbiol. Sinica
14 Analysis of the structure of polysaccharide from the fermentation broth of Ganoderma lucidum /
[ Luo, L. X.;S. Q. Zhou;R. H. Yao ] / Analytical Lab.
15 Immuno-modulatory substance of fungal origin /
[ Jong, S. C.;J. M. Birmingham;S. H. Pai. ] / J. Immunol. Immuno-pharmacol.
16 The gel-filtration behariour of proteins related to their molecular weighs over a wide range /
[ Andrews, P. ] / Biochem. J.   DOI
17 A colorimetric method for the determination of serum glutamic oxaloacetic and glutamic pyruvic transaminases /
[ Reitman, S.;S. Frankel ] / Am. J. Clin. Pathol.   DOI