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http://dx.doi.org/10.1080/12298093.2019.1628521

Bisifusarium Delphinoides, an Emerging Opportunistic Pathogen in a Burn Patient with Diabetes Mellitus  

Park, Ji-Hyun (Translational Research Division, Biomedical Institute of Mycological Resource, International St. Mary's Hospital and College of Medicine, Catholic Kwandong University)
Oh, Junsang (Translational Research Division, Biomedical Institute of Mycological Resource, International St. Mary's Hospital and College of Medicine, Catholic Kwandong University)
Song, Ji-Sun (Department of Pathology, International St. Mary's Hospital, Catholic Kwandong University)
Kim, Jayoung (Department of Laboratory Medicine, International St. Mary's Hospital, Catholic Kwandong University)
Sung, Gi-Ho (Translational Research Division, Biomedical Institute of Mycological Resource, International St. Mary's Hospital and College of Medicine, Catholic Kwandong University)
Publication Information
Mycobiology / v.47, no.3, 2019 , pp. 340-345 More about this Journal
Abstract
An 82-year-old man with diabetes was admitted to the emergency department with a third-degree burn on his left leg. The deep swab specimen from his left leg was cultured on Sabouraud dextrose agar without cycloheximide and incubated at $25^{\circ}C$ for 5 days. On the basis of morphological characteristics and multigene phylogenetic analyses of the internal transcribed spacer region of ribosomal DNA and partial fragments of beta-tubulin and translation elongation factor 1-alpha, the causal agent of fungal skin infection was identified as Bisifusarium delphinoides, which was newly introduced by accommodating a Fusarium dimerum species complex. Thus, we describe here the first case of skin infection caused by B. delphinoides on a burn patient with diabetes mellitus based on morphological observation and molecular analysis.
Keywords
Antifungal susceptibility; FDSC; opportunistic pathogen; phylogenetic analysis;
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