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http://dx.doi.org/10.4489/MYCO.2011.39.1.012

Assessment of Antioxidant and Phenolic Compound Concentrations as well as Xanthine Oxidase and Tyrosinase Inhibitory Properties of Different Extracts of Pleurotus citrinopileatus Fruiting Bodies  

Alam, Nuhu (Division of Life Sciences, University of Incheon)
Yoon, Ki-Nam (Division of Life Sciences, University of Incheon)
Lee, Kyung-Rim (Division of Life Sciences, University of Incheon)
Kim, Hye-Young (Division of Life Sciences, University of Incheon)
Shin, Pyung-Gyun (Mushroom Division, National Institute of Horticultural and Herbal Science, Rural Development Administration)
Cheong, Jong-Chun (Mushroom Division, National Institute of Horticultural and Herbal Science, Rural Development Administration)
Yoo, Young-Bok (Mushroom Division, National Institute of Horticultural and Herbal Science, Rural Development Administration)
Shim, Mi-Ja (Department of Life Science, University of Seoul)
Lee, Min-Woong (Department of Biology, Dongguk University)
Lee, Tae-Soo (Division of Life Sciences, University of Incheon)
Publication Information
Mycobiology / v.39, no.1, 2011 , pp. 12-19 More about this Journal
Abstract
Cellular damage caused by reactive oxygen species has been implicated in several diseases, thus establishing a significant role for antioxidants in maintaining human health. Acetone, methanol, and hot water extracts of Pleurotus citrinopileatus were evaluated for their antioxidant activities against ${\beta}$-carotene-linoleic acid and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals, reducing power, ferrous ion-chelating abilities, and xanthine oxidase inhibitory activities. In addition, the tyrosinase inhibitory effects and phenolic compound contents of the extracts were also analyzed. Methanol and acetone extracts of P. citrinopileatus showed stronger inhibition of ${\beta}$-carotene-linoleic acid compared to the hot water extract. Methanol extract (8 mg/mL) showed a significantly high reducing power of 2.92 compared to the other extracts. The hot water extract was more effective than the acetone and methanole extracts for scavenging DPPH radicals. The strongest chelating effect (92.72%) was obtained with 1.0 mg/mL of acetone extract. High performance liquid chromatography analysis detected eight phenolic compounds, including gallic acid, protocatechuic acid, chlorogenic acid, ferulic acid, naringenin, hesperetin, formononetin, and biochanin-A, in an acetonitrile and hydrochloric acid (5 : 1) solvent extract. Xanthine oxidase and tyrosinase inhibitory activities of the acetone, methanol, and hot water extracts increased with increasing concentration. This study suggests that fruiting bodies of P. citrinopileatus can potentially be used as a readily accessible source of natural antioxidants.
Keywords
Antioxidant; Phenolic compounds; Pleurotus citrinopileatus; Tyrosinase inhibition; Xanthine oxidase;
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