Antitumor Effects and Immunomodulating Activities of Phellinus linteus Extract in a CT-26 Cell-Injected Colon Cancer Mouse Model |
Yang, Byung-Keun
(Department of Biotechnology, Catholic University of Daegu)
Hwang, Seung-Lark (Research Institute of Biomedical Engineering and Department of Medicine, Catholic University of Daegu) Yun, Ik-Jin (Department of Surgery, College of Medicine, Konkuk University) Do, Eun-Ju (Dong-A University Hospital Clinical Research Center) Lee, Won-Ha (School of Life Sciences and Biotechnology, Kyungpook National University) Jung, Young-Mi (Zenitec Korea Co) Hong, Sung-Chang (Zenitec Korea Co) Park, Dong-Chan (Zenitec Korea Co) |
1 | Arthur, M. J. P., Saunders, P. K. and Wright, R. 1989. Corynebacterium parvum-elicited hepatic macrophages demonstrate enhanced respiratory burst activity compared with resident Kupffer cells in the rat. Gastroenterol. 91:175-181. |
2 | Chihara, G., Hanuram, J., Maeda, Y., Arai, Y. and Fukuoka, F. 1970a. Antitumor polysaccharide derived chemically from natural glucan (pachyman). Nature 225:943-944. DOI ScienceOn |
3 | Feron, E. R. 1997. Human cancer syndromes. Cules to the origin and nature of cancer. Science 278:1043-1050. DOI ScienceOn |
4 | Frank, L. and Teich, M. 1997. Introduction to cellular and molecular biology of cancer. Part 3. Epidermiology of cancer. Oxford University Press. 45-46 |
5 | Hwang, Y. J., Nam, H. K., Chang, M. J., Noh, G. W. and Kim, S. H. 2003. Effect of Lentinus edodes and Pleurotus eryngii extracts on proliferation and apotosis in human colon cancer cell lines. J. Korean Soc. Food Sci. Nutr. 32:217-222. |
6 | Ikekawa, T., Nakanishi, M., Uehara, N., Chihara, G. and Fukuoka, F. 1968. Antitumor action of some basidiomycetes, especially Phellinus linteus. Gann. 59:155-157. |
7 | Kim, H. M., Han, S. B., Oh, G. T., Kim, Y. H., Hong, D. H., Hong, N. D. and Yoo, I. D. 1996. Stimulation of humoral and cell mediated immunity by polysaccharide from mushroom Phellinus linteus. Int. J. Immunopharmacol. 18:295-303. DOI ScienceOn |
8 | Kodama, N., Komuta, K., Sakai, N. and Nanba, H. 2002. Effects of D-fraction, a polysaccharide from Grifola frondosa on tumor growth, involve activation of NK cells. Biol. Pharm. Bull. 25:1647-1650. DOI ScienceOn |
9 | Chihara, G., Hanuram, J., Maeda, Y., Arai, Y. and Fukuoka, F. 1970b. Fractionation and purification of the polysaccharides with marked antitumor activity, especially lentinan, from Lentinus edodes (Berk) Sing (an edible mushroom). Cancer Res. 30: 2776-2781. |
10 | Duncan, D. B. 1957. Multiple range tests for correlated and heteroscedastic means. Biometrics 13:164-176. DOI ScienceOn |
11 | Jeong, S. C., Cho, S. P., Yang, B. K., Jeong, Y. T., Ra, K. S. and Song, C. H. 2004. Immunomodulating activity of the exopolymer from submerged mycelia culture of Phellinus pini. J. Microbiol. Biotechnol. 14:15-21. |
12 | Tsuru, S., Shinomiya, N., Katsura, Y., Gotoh, M., Noritake, M. and Nomoto, K. 1991. Effects of combined therapies with protein-bound polysaccharide (PSK, krestin) and fluorinated pyrimidine derivatives on experimental liver metastases and on the immunologic capacities of the hosts. Oncology 48:498-504. DOI ScienceOn |
13 | Lee, J. H., Cho, S. M., Song, K. S., Hong, N. D. and Yoo, I. D. 1996. Characterization of carbohydrate-peptide linkage of acidic heteroglycopeptide with immuno-stimulating activity from mycelium of Phellinus linteus. Chem. Pharm. Bull. 44:1093-1095. |
14 | Maeda, Y. Y. and Chihara, G. 1971. Lentinan, a new immunoaccelerator of cell-mediated responses. Nature 229:634. DOI ScienceOn |
15 | Rhee, Y. K., Han, M. J., Park, S. Y. and Kim, D. H. 2000. In vitro and in vivo antitumor activity of the fruit body of Phellinus linteus. Kor. J. Food Sci. Technol. 32:477-480. |
16 | Song, C. H., Ra, K. S., Yang, B. K. and Jeon, Y. J. 1998. Immuno-stimulating activity of Phellinus linteus. Kor. J. Mycol. 26:86-90. |
17 | Suzuki, H., Hyama, K., Yoshida, O., Yamazaki, S., Yamamoto, N. and Toda, S. 1990. Structural characterization of the immunoreactive and antiviral water-solubilized lignin in an extract of the culture medium of Lentinus edodes mycelia (LEM). Agric. Biol. Chem. 54:479-487. |
18 | Kabat, E. E. and Mayer M. M. 1964. Complement fixation. In: Experimental Immunology. Charles C. Thomas Publisher: Ilinois, 133 |
19 | Takeda, T., Shibata, S. and Fukuoka, F. 1969. Further investigation of the structure and the antitumor activity of the polysaccharides from Gyrophora esculenta and Lasallia papulosa. Chem. Pharm. Bull. 17:1910-1916. |
20 | Jung, Y. S., Yang, B. K., Jeong, Y. T., Islam, R., Kim, S. M. and Song, C. H. 2008. Immunomodulating activities of water-soluble exopolysaccharides obtained from submerged culture of Lintinus lepideus. J. Microbiol. Biotechnol. 18:1431-1438. |
21 | Kiho, T., Shiose, Y., Nagai, K. and Ukai, S. 1992. Polysaccharides in fungi. XXX. Antitumor and immunomodulating activities of two polysaccharides from the fruiting bodies of Armillariella tabescens. Chem. Pharm. Bull. 40:2110-2114. |
22 | Page, R. C., Davies, P. and Allison, A. C. 1978. The macrophage as a secretory cell. Int. Rev. Cytol. 52:119-123. DOI |
23 | Mizuno, T. 2000. Development of an antitumor biological response modifier from Phellinus linteus (Berk. Et Curt.) Teng(Aphyllophoromycetideae) (Review). Int. J. Med. Mushr. 2:21-34. |
24 | Nomoto, K., Yoshikumi, C., Matsunaga, K., Fuji, T. and Takeya, K. 1975. Restoration of antibody-forming capacities by PS-Kin tumor-bearing mice. Gann. 66:365-374. |
25 | Lee, H. K., Shin, K. S., Song, C. H., Sung, H. J. and Yang, H. C. 1994. The effect of nutrients on the production of anti-complementary polysaccharide by Flammulina velutipes. Kor. J. Appl. Microbiol. Biotechnol. 22:360-367. |
26 | Tabata, K., Itoh, W., Kojima, I., Kawabate, S. and Misaki, K., 1981. Ultrasonic degradation of schizophyllan and antitumor polysaccharide produced by Schizophyllum commune. Carbohydr. Res. 89:121-135. DOI ScienceOn |
27 | Wasser, S. P. 2002. Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides. Appl. Microbiol. Biotechnol. 60:258-274. |
28 | Oh, G. T., Han, S. B., Kim, H. M., Han, M. W. and Yoo, I. D. 1992. Immunostimulating activity of Phellinus linteus extracts to B-lymphocyte. Arch. Pharm. Res. 15:379-381. DOI |
29 | Okuda, T., Yoshioka, Y., Ikekawa, T., Chihara, G. and Nishioka, K. 1972. Anti-complementary activity of anti-tumor polysaccharides. Nature: New Biol. 238:59-60. DOI ScienceOn |
30 | Yang, Q. T., Jong, S. C., Li, X. Y., Zhou, J. X., Chen, R. T. and Xu, L. Z. 1992. Antitumor and immunomodulating activities of the polysaccharopeptide-peptide (PSP) of Coriolus versicolor. J. Immunol. Immunopharmacol. 12:29-34. |
31 | Zheng, R., Jie, S., Hanchuan, D. and Moucheng, W. 2005. Characterization and immunomodulating activities of polysaccharide from Lentinus edodes. Int. Immunopharmacol. 5:811-820 DOI ScienceOn |
32 | Chung, K. S., Kim, S. S., Kim, H. S., Kim, K. Y., Han, M. W. and Kim, K. H. 1993. Effect of Kp, an antitumor proteinpolysaccharide from mycelial culture of Phellinus linteus on the humoral immune reponse of tumor bearing ICR mice to sheep red blood cells. Arch. Pharm. Res. 16:336-338. DOI |
33 | Maroun, J. A., Anthony, L. B., Blais, N., Burkes, R., Dowden, S. D., Dranitsaris, G., Samson, B., Shah, A., Thirlwell, M. P., Vincent, M. D. and Wong, R. 2007. Prevention and management of chemotherapy-induced diarrhea in patients with colorectal cancer: A consensus statement by the Canadian working group on chemotherapy-induced diarrhea. Curr. Oncol. 14:13-20. DOI ScienceOn |
34 | Jeong, Y. T., Yang, B. K., Jeong, S. C., Kim, S. M. and Song, C. H. 2008. Ganoderma applanatum: A promising mushroom for antitumor and immunomodulating activity. Phytother. Res. 22:614-619. DOI ScienceOn |
![]() |