Browse > Article
http://dx.doi.org/10.4489/MYCO.2008.36.4.233

Chemical Ingredients of Cordyceps militaris  

Hur, Hyun (Department of Life Science, Dongguk University)
Publication Information
Mycobiology / v.36, no.4, 2008 , pp. 233-235 More about this Journal
Abstract
Medicinal mushrooms, including Cordyceps militaris, have received attention in Korea because of their biological activities. In the fruiting body and in corpus of C. militaris, the total free amino acid content was 69.32 mg/g and 14.03 mg/g, respectively. In the fruiting body, the most abundant amino acids were lysine, glutamic acid, proline and threonine. The fruiting body was rich in unsaturated fatty acids, which comprised about 70% of the total fatty acids. The most abundant unsaturated acid was linoleic acid. There were differences in adenosine and cordycepin contents between the fruiting body and the corpus. The adenosine concentration was 0.18% in the fruiting body and 0.06% in the corpus, and the cordycepin concentration was 0.97% in the fruiting body and 0.36% in the corpus.
Keywords
Adenosine; Amino acid; Cordycepin; Cordyceps militaris; Fatty acid;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 Chang, H. L., Chao, G. R., Chen, C. C. and Mau, J. L. 2001. Non-volatile taste components of Agaricus blazei, Antrodia camphorata and Cordyceps militaris mtcelia. Food Chem. 74:203-207   DOI   ScienceOn
2 Bok, J. W., Lermer, L., Chilton, J., Klingeman, H. G. and Towers, G. H. 1999. Antitumor sterols from the mycelia of Cordyceps sinensis. Phytochemistry 51:891-898   DOI   ScienceOn
3 Chiou, W. F., Chang, P. C., Chou, C. J. and Chen, C. F. 2000. Protein constituent contributes to the hypotensive and vasorelaxant activities of Cordyceps sinensis. Life Sci. 66:1369-1376   DOI   ScienceOn
4 Hong, I. P., Nam, S. H., Sung, G. B., Chung, I. M., Hur, H., Lee, M. W., Kim, M. K. and Guo, S. H. 2007. Chemical components of Paecilomyces tenupes (Peck) Samson. Mycobiology 35:215-218   과학기술학회마을   DOI   ScienceOn
5 Spatafora, J. W. and Blackwell, M. 1993 .Molecular systematics of unitunicate perithecia ascomycetes; the Clavicipitales-Hypocreales connection. Mycologia 85:912-922   DOI
6 Yun, Y. H., Han, S. H., Lee, S. J., Ko, S. K., Lee, C. K., Ha, N. J. and Kim, K. J. 2003. Anti-diabetic effects of CCCA, CMESS and cordycepin from C. militaris and the immune responses in streptozotocin-induced diabetic mice. Kor. J. Nat. Product Sci. 9:291-298
7 Kuo, Y. C., Lin, C. Y., Tsai, W. J., Wu, C. L., Chen, C. F. and Shiao, M. S. 1994. Growth inhibitors against tumor cells in Cordyceps sinensis other than cordycepin and polysaccharides. Cancer Invest. 12:611-615   DOI   ScienceOn
8 Chen, H. K. 1986. Studies on the characteristics of taste-active components in mushroom concentrate and its powderization. Master's Thesis, National Chung-Hsing University, Taichung, Taiwan
9 Furuya, T., Hirotani, M. and Matsuzawa, M. 1983. $N^6$-(2-hydroxyethyl) adenosine, a biologically active compound from cultured mycelia of Cordyceps and Isaria species. Phytochemistry 22:2509-2512   DOI   ScienceOn
10 Huang, B. M., Stocco, D. M. and Norman, R. L. 1997. The cellular mechanism of corticotropin-releasing hormone (CRH) stimulated steroidogenesis in mouse Leydig cells are similar to those for LH. J. Androl. 18:528-534
11 Kuo, Y. C., Tsai, W. J., Shiao, M. S., Chen, C. F. and Lin, C. Y. 1996. Cordyceps sinensis as an immunomodulatory agent. Am. J. Chin. Med. 24:111-125   DOI   ScienceOn
12 Li, Q. S., Zeng, W., Yi, D. H. and Huang, T. F. 1998. Studies on the alternation of generations in Cordyceps sinensis. Chung Kuo Yao Tsa Chil. 23:210-212
13 Manabe, N., Sugimoto, M., Azuma, Y., Taketomo, N., Yamashita, A., Tsuboi, H., Tsunoo, A., Kinjo, N., Nian-Lai, H. and Miyamoto, H. 1996. Effect of the mycelial extract of cultured Cordyceps sinensis on in vivo hepatic energy metabolism in the mouse. Jpn. J. Pharmacol. 70:23-29
14 Wu, C. S., Leu, S. F., Yang, H. Y. and Huang, B. M. 2001. Melatonin inhibits the expression of steroidogenic acute regulatory protein and steroidogenesis in MA-10 cells. J. Androl. 22:245-254
15 Kim, K. M., Kwon, Y. G., Chung, H. T., Yun, Y. G., Pae, H. O., Han, J. A., Ha, K. S., Kim, T. W. and Kim, Y. M. 2003. Methanol extract of Cordyceps pruinosa inhibits in vitro and in vivo inflammatory mediators by suppressing NF-$\kappa$B activation. Toxicol. Appl. Pharm. 190:1-8   DOI   ScienceOn
16 82Kobayashi, Y. 1982. Key to the taxa of the genera Cordyceps and Torrubiella. Trans. Mycol. Soc. Jpn. 23:29-364
17 Wang, S. M., Lee, L. J., Lin, W. W. and Chang, C. M. 1998. Effect of a water-soluble extract of Cordyceps sinensis on steroidogenesis and capsular morphology of lipid droplet in cultured rat adrenocortical cell. J. Cell Biochem. 69:483-489   DOI   ScienceOn