Characteristics of HIV-Tat Protein Transduction Domain
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Yoon Jong-Sub
(Department of Microbiology, The Catholic University of Korea)
Jung Yong-Tae (Department of Microbiology, College of Advanced Science, Dankook University) Hong Seong-Karp (Catholic Hemopoietic Stem Cell Transplantation Center, The Catholic University of Korea) Kim Sun-Hwa (Department of Microbiology, The Catholic University of Korean) Shin Min-Chul (Department of Microbiology, The Catholic University of Korean) Lee Dong-Gun (Department of Internal Medicine, College of Medicine, The Catholic University of Korea) Shin Wan-Shik (Department of Internal Medicine, College of Medicine, The Catholic University of Korea) Min Woo-Sung (Department of Internal Medicine, College of Medicine, The Catholic University of Korea) Paik Soon-Young (Department of Microbiology, The Catholic University of Korea) |
1 | Elliger, S., C.A. Elliger, C. Lang, and G.L. Watson. 2002. Enhanced secretion and uptake of beta-glucuronidase improves adenoassociated viral-mediated gene therapy of mucopolysaccharidosis type VII mice. Mol Ther. 5, 617-626 |
2 | Elliott, G. and P. O'Hare. 1997. Intercellular trafficking and protein delivery by a herpesvirus structural protein. Cell. 88, 223-233 DOI ScienceOn |
3 | Han, K., M.J. Jeon, K.A. Kim, J. Park, and S.Y. Choi. 2000. Efficient intracellular delivery of GFP by homeodomains of Drosophila Fushi-tarazu and engrailed proteins. Mol. Cells 10, 728-732 |
4 | O'Reilly, D.R., L.K. Miller, and V.A. Luckow. 1992. Baculovirus Expression Vectors: A Laboratory Manual, Oxford Univ Press, New York, USA |
5 | Schwarze, S.R., A. Ho, A. Vocero-Akbani, and S.F. Dowdy. 1999. In vivo protein transduction: delivery of a biologically active protein into the mouse. Science 285, 1569-1572 |
6 | Silhol, M., M. Tyagi, M. Giacca, B. Lebleu, and E. Vives. 2002. Different mechanisms for cellular internalization of the HIV-1 Tat-derived cell penetrating peptide and recombinant proteins fused to Tat. Eur. J. Biochem. 269, 494-50 |
7 | Schwarze, S. R. and S. F. Dowdy. 2000. In vivo protein transduction: intracellular delivery of biologically active protein, compounds and DNA. Trends, Pharm, Science. 21, 45-48 |
8 | Joliot, A., C. Pernelle, H. Deagostini-Bazin, and A. Prochiantz. 1991. Antennapedia homeobox peptide regulates neural morphogenesis. Proc. Natl. Acad. Sci. USA. 88, 1864-1868 |
9 | Vives, E., P. Brodin, and B. Lebleu. 1997. A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J. Biol. Chem. 272, 16010-16017 DOI ScienceOn |
10 | Schwarze, S.R. and S.F. Dowdy. 2000. In vivo protein transduction: Intracellular delivery of biologically active proteins, compounds and DNA. Trends. Pharmacol. Sci. 21, 45-48 |
11 | Park, J., J. Ryu, K.A. Kim, H.J. Lee, J.H. Bahn, K. Han, E.Y. Choi, K.S. Lee, H.Y. Kwon, and S.Y. Choi. 2002. Mutational analysis of a human immunodeficiency virus type 1 Tat protein transduction domain which is required for delivery of an exogenous protein into mammalian cells. J. Gen. Virol. 83, 1173-1181 |
12 | Park, S.W., H.K. Lee, T.G. Kim, S.K. Yoon, and S.Y. Paik. 2001. Hepatocyte-specific gene expression by baculovirus pseudotyped with vesicular stomatitis virus envelope glycoprotein. Biochem. Biophys. Res. Commun. 289, 444-450 |
13 | Ryu, J.Y., K.Y. Han, J.S. Park, and S.Y. Choi. 2003. Enhanced uptake of a heterologous protein with an HIV-1 Tat protein transduction domains (PTD) at both termini. Mol. Cells. 16, 385-391 |
14 | Futaki, S., T. Suzuki, W. Ohashi, T. Yagami, S. Tanaka, K. Ueda, and Y. Sugiura. 2001. Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery. J. Biol. Chem. 276, 5836-5840 DOI ScienceOn |
15 | Leifert, J.A., S. Harkins, and J.L. Whitton. 2002. Full-length proteins attached to the HIV tat protein transduction domain are neither transduced between cells, nor exhibit enhanced immunogenicity. Gene Ther. 9, 1422-1428 |
16 | Xia, H., Q. Mao, and B.L. Davidson. 2001. The HIV Tat protein transduction domain improves the biodistribution of beta-glucuronidase expressed from recombinant viral vectors. Nat. Biotechnol. 19, 640-644 |
17 | Green, M. and P.M. Loewenstein. 1988. Autonomous functional domains of chemically synthesized human immunodeficiency virus tat trans-activator protein. Cell 55, 1179-1188 |
18 | Gao, G.P., Y. Yang, and J.M. Wilson. 1996. Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy. J. Virol. 70, 8934-8943 |
19 | Ho, A., S.R. Schwarze, S.J. Mermelstein, G. Waksman, and S.F. Dowdy. 2001. Synthetic protein transduction domains: enhanced transduction potential in vitro and in vivo. Cancer. Res. 61, 474-477 |
20 | Lieber, A., C.Y. He, L. Meuse, D. Schowalter, I. Kirillova, B. Winther, and M.A. Kay. 1997. The role of Kupffer cell activation and viral gene expression in early liver toxicity after infusion of recombinant adenovirus vectors. J. Virol. 71, 8798-8807 |
21 | Frankel, A.D. and C.O. Pabo. 1988. Cellular uptake of the tat protein from human immunodeficiency virus. Cell. 55, 1189-1193 |
22 | Derossi, D., A.H. Joliot, G. Chassaing, and A. Prochiantz. 1994. The third helix of the Antennapedia homeodomain translocates through biological membranes. J. Biol. Chem. 269, 10444-10450 |
23 | Nagahara, H., A.M. Vocero-Akbani, E.L. Snyder, A. Ho, D.G. Latham, N.A. Lissy, M. Becker-Hapak, S.A. Ezhevsky, and S.F. Dowdy. 1998. Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration. Nature Medicine 4, 1449-1452 |
24 | Bradford, M. A. 1976. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254 |
25 | Bao, J.J., W.W. Zhang, and M.T. Kuo. 1996. Adenoviral delivery of recombinant DNA into transgenic mice bearing hepatocellular carcinomas. Hum Gene Ther. 7, 355-365 |
26 | Wender, P.A., D.J. Mitchell, K. Pattabiraman, E.T. Pelkey, L. Steinman, and J.B. Rothbard. 2000. The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters. Proc. Natl. Acad. Sci. USA. 97, 13003-13008 |
27 | Moon, M.S., G.C. Lee, and C.H. Lee. 2002. Induction of Apopotosis in Human Monocytes by Human Cytomegalovirus is Related with Calcium Increase. J. Microbiol. 40, 224-229 |
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