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Characterization of a Streptomycete Isolate Producing the Potent Cytotoxic Substance, Nonadecanoic Acid  

Seong, Chi-nam (Department of Biology, Sunchon National University, Sunchon, 540-742)
Baik, Keun-shilk (Department of Biology, Sunchon National University, Sunchon, 540-742)
Jo, Jung-sun (Department of Biology, Sunchon National University, Sunchon, 540-742)
Yoo, Jin-cheol (Department of Pharmacy, Chosun University, Gwangju, 501-759)
Han, Ji-Man (Department of Pharmacy, Chosun University, Gwangju, 501-759)
Nam, Seung-Kwon (Department of Pharmacy, Chosun University, Gwangju, 501-759)
Publication Information
Journal of Microbiology / v.40, no.2, 2002 , pp. 178-181 More about this Journal
Abstract
Streptomycete isolator strain M0137 showed cytotoxic effect on THP-1 cells. One of the purified substances produced from the strain was identified as nonadecanoic acid. Morphological and physiological properties, phylogenetic analysis, and genomic fingerprinting of strain M0137 were determined. Strain M0137 showed a high similarity with Streptomyces scabiei, phenotypically and phylogenetically. In contrast, genomic fingerprinting and G+C content analysis revealed that strain M0137 could be distinguished from S. scabiei ATCC49173$\^$T/. We propose to name strain M0137 as Streptomyces scabiei Subsp.
Keywords
cytotoxic substance; nonadecanoic acid; genomic fingerprinting; Streptomyces scabiei subsp; chosunensis;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
Times Cited By Web Of Science : 3  (Related Records In Web of Science)
Times Cited By SCOPUS : 4
연도 인용수 순위
1 Isolation and characterization of nonadecanoic acid produced by Streptomyces scabies subsp. /
[ Nam, S.K. ] / chosunensis. M.S. thesis.
2 Genomic fingerprinting of bacteria using repitative sequencebased polymerase chain reaction /
[ Versalovic, J.;M. Schneider;F.J. Bruijn;J.R. Lupski ] / Methods Mol. Cell. Biol.
3 Inhibition of human NK cell function by valinomycin a toxin from Streptomyces griseus in indoor air /
[ Paananen A.;R. Mikkola;T. Sareneva;S. Matikainen;M. Andersson;I. Julkunen;M.S. Salkinoja-Salonen;T. Timonen ] / Infect. Immun.   DOI   ScienceOn
4 The neighbor-joining method: a new method for reconstructing phylogenetic trees /
[ Saitou, N.;M. Nei ] / Mol. Biol. Evol.
5 A piecemeal description of Streptomyces griseus (Krainsky) Waksman and Henrichi /
[ Gordon, R.E.;C. Horan ] / J. Gen. Microbiol.   DOI   ScienceOn
6 Effects of traditional crude druge on fibrinolysis by plasmin: antiplasmin principles in Eupolyphaga /
[ Kawashiri, N.;K. Toriizuka;I. Adachi;M. Ueno;K. Terasawa;I. Jorikoshi ] / Chem. Pharm. Bull.   DOI   ScienceOn
7 A phylogenetic analysis of the genus Nocardia with 16S rRNA gene sequences /
[ Chun, J.;M. Coodfellow ] / Int. J. Syst. Bacteriol.   DOI   ScienceOn
8 Migrastatin, a new inhibitor of tumor cell migration from Streptomyces sp. MK929-43F1. Taxonomy, Fermentation, isolation and biological activities /
[ Nakae K.;Y. Yoshimoto;T. Sawa;Y. Homma;M. Hamada;T. Takeuchi;M. Imoto ] / J. Antibiot.   DOI   ScienceOn
9 Phylogenetic analysis of Streptomyces spp. causing potato scab based on 16S rRNA sequences /
[ Takeuchi, T.;H. Sawada;F. Tanaka;I. Matsuda ] / Int. J. Syst. Bacteriol.   DOI   ScienceOn
10 /
[ Lambert D.H.;R. Loria ] / Streptomyces scabies sp. nov. nom. rev. Int. J. Syst. Bacteriol.   DOI
11 A comparative study of the ribosomal RNA operons of Streptomyces coelicolor A3(2) and sequence analysis of rRNA /
[ Van Wezel, G.P.;E. Vijgenboom;L. Bosch ] / Nucleic Acids Res.   DOI   ScienceOn
12 Rapid extraction of bacterial genomic DNA with guanidium thiocyanate /
[ Pitcher, D.G.;N.A. Saunders;R.J. Owen ] / Lett. Appl. Microbiol.   DOI
13 Use of ultrviolet absorbance temperature profile for determining the guanine plus cytosine content of DNA /
[ Mandel, M.;J. Marmur ] / Methods Enzymol.
14 Application of tissue culture micrtitre test for the detection of cytotoxic agents from natural products /
[ Mirabelli, C.K.;H. Bartus;J.O.L. Bartus;R. Johnson;S.M. Mong;S.P. Sung;S. T. Crroke ] / J. Antibiot.   DOI
15 Analysis of thermophilic clades within the genus streptomyces by 16S ribosomal DNA sequence comparisons /
[ Kim, D.;J. Chun;N. Sahin;Y.C. Hah;M. Goodfellow ] / Int. J. Syst. Bacteriol.   DOI
16 Designation of streptomycete 16S and 23S rRNA-based target regions of oligonucleotide probes /
[ Stackebrandt, E.;D. Witt;C. Kemmerling;R.M. Kroppenstedt;W. Liesack ] / Appl. Environ. Microbiol.
17 Biosynthetic intermediates of the tetradehydro cyclic dipeptide albonoursin produced by Streptomyces albulus KO-23 /
[ Kanzaki H.;S. Yanagisawa;T. Nitoda ] / J. Antibiot   DOI   ScienceOn
18 Methods for characterization of Streptomyces species /
[ Shirling, E.B.;D. Gottlieb ] / Int. J. Syst. Bacteriol.   DOI
19 Numerical classification of Streptomyces and related genera /
[ Williams, S.T.;M. Goodfellow;G. Alderson;E.M.H. Wellington;P.H.A. Sneath;M.J. Sackin ] / J. Gen. Microbiol.
20 Numerical analysis of chemotaxanomic data /
[ O'Donnell, A.G.;M. Goodfellow(eds.);D. Jones(eds.);F.G. Priest(eds.) ] / Computer assisted bacterial systematics
21 Isolation and structure elucidation of vicenistatin M and importance of the vicenisamine aminosugar for exerting cytotoxicity of vicenistatin /
[ Matsushima Y.;T. Nakayama;M. Fujita;R. Bhandari;T. Eguchi;K. Shindo;K. Kakinuma ] / J. Antibiot   DOI   ScienceOn
22 /
[ Buchann, R.E.;N. E. Gibbons(ed.) ] / Bergey's Manual of Determinative Bacteriology.(8th ed.)
23 Selection of microbial sources of bioactive compounds /
[ Iwai, H.;Y. Takahashi;S. Oumara(ed.) ] / The Search for bioactive compounds from microorganisms