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http://dx.doi.org/10.7852/ijie.2012.25.1.129

Tetracycline-incorporated Silk Fibroin Films  

Kim, Jong-Ho (School of Textile Engineering and Fashion Design, Kyungpook National University)
Shin, Bong-Seob (School of Textile Engineering and Fashion Design, Kyungpook National University)
Jeon, Jong-Young (School of Textile Engineering and Fashion Design, Kyungpook National University)
Kweon, Hae-Yong (Sericultural & Apicultural Materials Division, National Academy of Agricultural Science, RDA)
Jo, You-Young (Sericultural & Apicultural Materials Division, National Academy of Agricultural Science, RDA)
Lee, Heui-Sam (Sericultural & Apicultural Materials Division, National Academy of Agricultural Science, RDA)
Lee, Kwang-Gill (Sericultural & Apicultural Materials Division, National Academy of Agricultural Science, RDA)
Publication Information
International Journal of Industrial Entomology and Biomaterials / v.25, no.1, 2012 , pp. 129-132 More about this Journal
Abstract
Silk fibroin films incorporated with tetracycline was prepared and characterized by Fourier-transform infrared spectrometer and differential scanning calorimeter and examined antibacterial effect. The conformation of silk fibroin was changed from random coil to $\hat{a}$ sheet structure with incorporation of tetracycline. Antibacterial activity of the materials was evaluated against Gram-negative bacteria (Escherichia coli) and Gram-positive bacteria (Staphylococcus epidermis, and Staphylococcus aures) using agar plate method showing clear inhibition zone around tetracycline silk film. It is concluded that tetracycline-incorporated SF films are highly effective against bacteria.
Keywords
Silk fibroin; Tetracycline; Conformation; Antimicrobial; Bacteria;
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Times Cited By KSCI : 1  (Citation Analysis)
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