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http://dx.doi.org/10.7852/ijie.2011.23.1.143

Effect of Cordyceps militaris on Testosterone Production in Sprague-Dawley Rats  

Hong, In-Pyo (National Academy of Agricultural Science, Rural Development Administration)
Choi, Yong-Soo (National Academy of Agricultural Science, Rural Development Administration)
Woo, Soon-Ok (National Academy of Agricultural Science, Rural Development Administration)
Han, Sang-Mi (National Academy of Agricultural Science, Rural Development Administration)
Kim, Hye-Kyung (National Academy of Agricultural Science, Rural Development Administration)
Lee, Man-Young (National Academy of Agricultural Science, Rural Development Administration)
Lee, Myung-Ryul (National Academy of Agricultural Science, Rural Development Administration)
Humber, Richard A. (USDA-ARS Biological Integrated Pest Management Research Unit, Robert W. Holly Center for Agriculture & Health)
Publication Information
International Journal of Industrial Entomology and Biomaterials / v.23, no.1, 2011 , pp. 143-146 More about this Journal
Abstract
Some of men have been suffered from the insufficient secretion of testosterone causing by physical factors, social and psychological factors. Testosterone is an essential steroid hormone controlling male reproductive function. Alternative medicines in plants, fungi, and insects have been studied to enhance sexuality. $Cordyceps$ species including $Cordyceps$ $sinensis$ (CS) and $C.$ $militaris$(CM) has been used as for the enhancement of sexual functionfor hundreds of years in Far East Asian. In the present study, we determined the effect of fruiting bodies of $C.$ $militaris$ which cultured on bee drone medium (CMD) and brown rice medium (CMB) on testosterone concentration in Sprague-Dawley rats. Eighteen rats per group were housed to regular diet or diet supplemented with CMB and CDD, respectively for 4 weeks. Serum was collected from 6 rats per group. Results showed that changes of the body weight, food and water intake of the rats were not observed in this study. However, both CMB and CDD increased the serum testosterone concentration in rats. Furthermore, CMD significantly stimulated testosterone production (p <0.05) compared to the control. Hence, it suggests that $C.$ $militaris$ fruiting bodymight be developed as a complementary medicine to improve sexual hormones.
Keywords
Brown rice; $Cordyceps$ $militaris$; Drone; Testosterone;
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