[KSCI] Korea Science Citation Index Service

http://dx.doi.org/10.20307/nps.2021.27.3.172

Sesbagrandiflorain F, a New 2-Arylbenzofuran from the Stem Bark of Sesbania grandiflora L.

Tanjung, Mulyadi (Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga)
Aldin, Muhammad Fajar (Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga)
Tjahjandarie, Tjitjik Srie (Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga)
Rahayu, Devina Oktari (Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga)
Gunawan, Alfiah Nur Irza (Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga)
Saputri, Ratih Dewi (Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Surabaya)

Publication Information

Natural Product Sciences / v.27, no.3, 2021 , pp. 172-175 More about this Journal

Abstract

Sesbagrandiflorain F (1), a novel 2-arylbenzofuran, and two more 2-arylbenzofurans (2-3), were isolated from the stem bark of Sesbania grandiflora L. Based on information HRESIMS data, 1D, and 2D NMR spectra, the structure of 1 was fully assigned. Compounds 1-3 were tested for cytotoxicity in MCF-7 and HeLa cells. Compounds 1 and 3 showed moderate activity against MCF-7 cells with an IC₅₀ value of 2.68 and 4.08 ㎍/mL, respectively. Conversely, all of the isolates were inactive towards HeLa cells.

Keywords

Sesbagrandiflorain F; 2-Arylbenzofuran; Sesbania grandiflora; Cytotoxic;

Citations & Related Records

Reference

1	Noviany, N.; Samadi, A.; Yuliyan, N.; Hadi, S.; Aziz, M.; Purwitasari, N.; Mohamad, S., Ismail, N. N.; Gable, K. P.; Mahmud, T. Phytochem. Lett. 2020, 35, 211-215. DOI
2	Fu, X-J.; Yi, J-L.; Yang, J-Y.; Lin, X-Q.; Huang, W.H., Zhou, X-M., Phytochem. Lett. 2021, 41, 106-108. DOI
3	Tjahjandarie, T. S.; Tanjung, M.; Saputri, R. D.; Rahayu, D. O.; Gunawan, A. N. I.; Aldin, M. F. Nat. Prod. Res. 2020, 2020, 1-6. DOI
4	Messens, E.; Montagu, M.; Bruyn, A.; Jans, A.W. H. Carbohydrate Res. 1989, 186, 241-253. DOI
5	Belofsky, G.; Carreno, R.; Lewis, K.; Ball, A.; Casadei, G.; Tegos, G. P. J. Nat. Prod. 2006, 69, 261-264. DOI
6	Saputri, R. D.; Tjahjandarie, T. S; Tanjung, M. Nat. Prod. Sci. 2018, 24, 155-158. DOI
7	Saputri, R. D.; Tjahjandarie, T. S.; Tanjung, M. Nat. Prod. Res. 2021, 35, 1256-1261. DOI
8	Tanjung, M.; Tjahjandarie, T. S.; Saputri, R. D.; Kurnia, B. D.; Rachman, M. F.; Syah, Y. M. Nat. Prod. Res. 2021, 35, 407-412. DOI
9	Tjahjandarie, T. S.; Tanjung, M.; Saputri, R. D.; Aldin, M. F.; Susanti, R. A.; Pertiwi, N. P.; Wibawa, R. S.; Halizah, I. N. Phytochem. Lett. 2021, 44, 78-81. DOI
10	Tanjung, M.; Rachmadiarti, F.; Prameswari, A.; Agyani, V. U. W.; Saputri, R. D.; Tjahjandarie, T. S.; Syah, Y. M. Nat. Prod. Res. 2018, 32, 1493-1498. DOI