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http://dx.doi.org/10.20307/nps.2017.23.2.146

Quantitative Analysis and Validation of Hirsutenone and Muricarpone B from Fermented Alnus sibirica  

YIN, Jun (Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University)
YOON, Ki Hoon (Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University)
YOON, Seong Hye (Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University)
AHN, Hye Shin (Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University)
LEE, Min Won (Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University)
Publication Information
Natural Product Sciences / v.23, no.2, 2017 , pp. 146-150 More about this Journal
Abstract
Alnus sibirica (AS) geographically distributes in Korea, Japan, Northeast China and Russia. The bark of this plant had been used for antipyretic, expectorant, anti-phlogistic, antitussive, anti-asthmatic and as a health tea for alcoholism. Recently, we studied various biological activities of AS and the isolated diarylheptanoid. In present study, we conducted fermentation of AS (FAS) and isolated two diarylheptanoid (hirsutenone and muricarpone B). Moreover, we established the validation and contents determinations of the two compounds by HPLC on FAS.
Keywords
Alnus sibirica; Fermentation; HPLC; Validation; Content;
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  • Reference
1 Lee, S. J. Korea folk Medicine; Seoul National University Publishing Center: Korea, 1996, pp40.
2 Asakawa, Y.; Genjida, F.; Hayashi, S.; Matsuura, T. Tetrahedron Lett. 1969, 10, 3235-3237.   DOI
3 Terazawa, M.; Okuyama, H.; Miyake, M. Mokuzai gakkaish 1973, 19, 45-46.
4 Karchesy, J. J.; Laver, M. L.; Barofsky, D. F.; Barofsky, E. J. Chem. Soc. 1974, 16, 649-650.
5 Nomura, M.; Tokoroyama, T.; Kubota, T. Phytochemistry 1981, 20, 1097-1104.   DOI
6 Suga, T.; Iwata, N.; Asakawa, Y. Bull. Chem. Soc. Jpn. 1972, 45, 2058-2060.   DOI
7 Asakawa, Y. Bull. Chem. Soc. Japan 1971, 44, 2761-2766.   DOI
8 Yoshida, T.; Memon, M. U.; Okuda, T. Heterocycles 1981, 16, 1085-1088.   DOI
9 Ishimatsu, M.; Tanaka, T.; Nonaka, G.; Nishioka, I. Phytochemistry 1989, 28, 3179-3184.   DOI
10 Khvorst, O. P.; Serbin, A. G.; Komissarenko, N. F.; Goldienko, V. G. Khim. Farm. Zh. 1989, 23, 445-449.
11 Lee, M. W.; Tanaka. T.; Nonaka, G.; Nishioka, I. Phytochemistry 1992, 31, 967-970.   DOI
12 Aoki, T.; Ohta, S.; Aratani, S.; Hirata, T.; Suga, T. J. Chem. Soc. Perkin Trans. 1. 1982, 2, 1399-1403.
13 Sakamura, F.; Ohta, S.; Aoki, T.; Syga, T. Phytochemistry 1985, 24, 2744-2745.   DOI
14 Suga, T.; Ohta, S.; Ohta, E.; Aoki, T. Phytochemistry 1986, 25, 1243-1244.   DOI
15 Bae, C. I.; Gong, J. M.; Oh, J. W.; Kim, H. J.; Oh, G. J.; Park, S. K.; Chung, S. G.; Cho, E. H. Yakhak Hoeji 1997, 41, 559-564.
16 Lee, M.; Song, J. Y.; Chin, Y. W.; Sung, S. H. Bioorg. Med. Chem. Lett. 2013, 23, 2069-2073.   DOI
17 Pahng, S. H. Korean J. Orient. Med. 2011, 17, 53-60.
18 Kim, K. Y.; Song, H. J. Herbal processology; Shinil Press: Korea, 2002, p 547.
19 Park, J. H.; Kim, H. J.; Lee, M. J. J. Soc. Korean Med. Obes. Res. 2009, 9, 1-14.
20 Kim, H. J.; Kim, K. H.; Yeom, S. H.; Kim, M. K.; Shin, J. G.; Lim, H. W.; Lee, M. W. Chinese Chem Lett. 2005, 16, 1337-1340.
21 Giang, P. M.; Son, P. T.; Matsunami, K.; Otsuka, H. Chem. Pharm. Bull. 2006, 54, 139-140.   DOI
22 Kim, M. H.; Park, K. H.; Kim, S. R.; Park, K. J.; Oh, M. H.; Heo, J. H.; Yoon, K. H.; Yin, J.; Yoon, K. H.; Lee, M. W. Nat. Prod. Res. 2016, 30, 206-213.   DOI
23 Kuroyanagi, M.; Shimomae, M.; Nagashima, Y.; Muto, N.; Okuda. T.; Kawahara, N.; Nakane, T.; Sano, T. Chem. Pharm. Bull. 2005, 53, 1519-1523.   DOI
24 Jeong, M. S.; Choi, S. E.; Kim, J. Y.; Kim, J. S.; Kim, E. J.; Park, K. H.; Lee, D. I.; Joo, S. S.; Lee, C. S.; Bang, H.; Lee, M. K.; Choi, Y. W.; Li, K. S.; Moon, N. J.; Lee, M. W.; Seo, S. J. Clin. Dev. Immunol. 2010, 2010, 618517.
25 Kim, J. H.; Lee, K. W.; Lee, M. W.; Lee, H. J.; Kim, S. H.; Surh, Y. J. FEBS Lett. 2006, 580, 385-392.   DOI
26 Choi, J. G.; Lee, M. W.; Choi, S. E.; Kim, M. H.; Kang, O. H.; Lee, Y. S.; Chae, H. S.; Obiang-Obounou, B.; Oh, Y. C.; Kim, M. R.; Shin, D. W.; Lee, J. H.; Kwon, D. Y. Eur. Rev. Med. Pharmacol. Sci. 2012, 16, 853-859.
27 Choi, J. G.; Lee, M. W.; Choi, S. E.; Kim, M. H.; Kang, O. H.; Lee, Y. S.; Chae, H. S.; Obiang-Obounou, B.; Oh, Y. C.; Kim, M. R.; Shin, D. W.; Lee, J. H.; Kwon, D. Y. Eur. Rev. Med. Pharmacol. Sci. 2012, 16, 853-859.