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http://dx.doi.org/10.20307/nps.2016.22.1.41

Flavonoid Glycosides from the Flowers of Pulsatilla koreana Nakai  

Seo, Kyeong-Hwa (Department of Oriental Medicine Biotechnology, Kyung Hee University)
Jung, Jae-Woo (Department of Oriental Medicine Biotechnology, Kyung Hee University)
Nhan, Nguyen Thi (Department of Oriental Medicine Biotechnology, Kyung Hee University)
Lee, Youn-Hyung (Department of Horticultural Biotechnology, Kyung Hee University)
Baek, Nam-In (Department of Oriental Medicine Biotechnology, Kyung Hee University)
Publication Information
Natural Product Sciences / v.22, no.1, 2016 , pp. 41-45 More about this Journal
Abstract
Extraction and fractionation of Pulsatilla koreana flowers followed by, repeated open column chromatography for EtOAc and n-BuOH fractions yielded four flavonoid glycosides, namely, astragalin (1), tiliroside (2), buddlenoide A (3), and apigenin-7-O-(3"-E-p-coumaroyl)-glucopyranoside (4). The chemical structures of these flavonoid glycosides were elucidated on the basis of various spectroscopic methods including electronic ionization mass spectrometry (EI-MS), 1D NMR ($^1H$, $^{13}C$, DEPT), 2D NMR (gCOSY, gHSQC, gHMBC), and infrared (IR) spectrometry. This study represents the first report of the isolation of the flavonoid glycosides from the flowers of P. koreana.
Keywords
Buddlenoide A; Flower; Pulsatilla koreana; Nuclear magnetic resonance; Tiliroside;
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