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Studies about Monoamine Oxidase Inhibitory Activities of Korean Green Tea (Teae sinensis L.) Harvested from Different Time and Location  

Choi, You Jin (Plant Resource Research Institute, Duksung Women's University)
Chong, Han-Soo (Department of Forest Products and Biotechnology, Kookmin University)
Kim, Young-Kyoon (Department of Forest Products and Biotechnology, Kookmin University)
Hwang, Keum Hee (Plant Resource Research Institute, Duksung Women's University)
Publication Information
Natural Product Sciences / v.19, no.4, 2013 , pp. 281-285 More about this Journal
Abstract
This study was designed to investigate the nervous sedative effects of green tea. The sedative effect was evaluated by examination of Monoamine oxidases (MAOs) inhibitory activity in vitro in the brain and liver of rat fed on green tea cultivated and harvested from the different regions and periods. It showed that methanol extracts of green tea inhibited significantly the brain MAO-A activity. Especially late harvested green tea extracts showed potential inhibitory activity. The liver MAO-B activity was also inhibited by all of the green tea extracts with strong intensity. This study confirmed that major compounds of green tea such as catechin, epigallocatechin-3-gallate (EGCG) and L-theanine, which were well known for the main bioactive components in the tea plants, were not associated with the MAO inhibitory activities of green tea. These results suggested that a MAO inhibition activity comes from other minor tea components we have to search in the future.
Keywords
Monoamine oxidase (MAO); Korean green tea; MAO inhibitor; Catechin; EGCG;
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