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Chemical Constituents of Plants from the Genus Patrinia  

Kim, Ju Sun (Natural Products Research Institute and College of Pharmacy, Seoul National University)
Kang, Sam Sik (Natural Products Research Institute and College of Pharmacy, Seoul National University)
Publication Information
Natural Product Sciences / v.19, no.2, 2013 , pp. 77-119 More about this Journal
Abstract
The genus Patrinia, belonging to the Valerianaceae family, includes ca. 20 species of herbaceous plants with yellow or white flowers, distributed in Korea, China, Siberia, and Japan. Among them, P. scabiosaefolia (yellow Patrinia), P. saniculaefolia, P. villosa (white Patrinia), and P. rupestris are found in Korea. Several members of this genus have long been used in folk medicine for the treatment of inflammation, wound healing, ascetics, and abdominal pain after childbirth. Thus far, ca. 217 constituents, namely flavonoids, iridoids, triterpenes, saponins, and others have been identified in this genus. Crude extract and isolated compounds have been found to exhibit anticancer, anti-inflammatory, antioxidant, antifungal, antibacterial, cytotoxic activities, lending support to the rationale behind several of its traditional uses. The present review compiles information concerning the phytochemistry and biological activities of Patrinia, with particular emphasis on P. villosa, as studied by our research group.
Keywords
Valerianaceae; Patrinia species; Natural products chemistry; Biological activities;
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