Methanol Extract of Zizyphi Spinosi Semen Augments Pentobarbital-Induced Sleep through the Modification of GABAergic Systems
![]() |
Hu, Zhenzhen
(College of Pharmac, Chungbuk National University)
Kim, Chung-Soo (College of Pharmac, Chungbuk National University) Oh, Eun-Hye (Department of Biochemistry, College of Medicine, Chungbuk National University) Lee, Mi-Kyung (College of Pharmacy, Woosuk University) Eun, Jae-Soon (College of Pharmacy, Woosuk University) Hong, Jin-Tae (College of Pharmac, Chungbuk National University) Oh, Ki-Wan (College of Pharmac, Chungbuk National University) |
1 | Cao, J.X., Zhang, Q.Y., Cui, S.Y., Cui, X.Y., Zhang, J., Zhang, Y.H. et al Hypnoticeffect of jujubosides from Semen Ziziphi Spinosae. Journal of Ethnopharmacology 130, 163-166 (2010). DOI ScienceOn |
2 | Doghramji, K. The epidemiology and diagnosis of insomnia. American Journal of Managed Care 12, 214 (2006). |
3 | Eun, J.S., Bae, K., Yun, Y.P., Hong, J.T., Kwon, H.N., and Oh, K.W., Inhibitory effects of paeonol on morphine-induced locomotor sensitization and conditioned place preference in mice. Archives of Pharmacal Research 29, 904-910 (2006). DOI ScienceOn |
4 | Fang, X., Hao, J.F., Zhou, H.Y., Zhu, L.X., Wang, J.H., and Song, F.Q., Pharmacological studies on the sedative-hypnotic effect of Semen Ziziphi spinosae (Suanzaoren) and Radix et Rhizoma Salviae miltiorrhizae (Danshen) extracts and the synergistic effect of their combinations. Phytomedicine 17, 75-80 (2010). DOI ScienceOn |
5 | Guevara, M., Ramos, J., Hernandez-Gonzalez, M., Zarabozo, D., and Corsi-Cabrera, M., POTENCOR: a program to calculate power and correlation spectra of EEG signals. Computer Methods and Programs in Biomedicine 72, 241-250 (2003). DOI ScienceOn |
6 |
Han, H.S., Ma, Y., Eun, J.S., Hong, J.T., and Oh, K.W., Anxiolytic-like effects of cyclopeptide fration alkaloids of zizyphi spinosi semen: possible involvement of |
7 | Houston, C.M. and Smart, T.G., CaMK-II modulation of GABA(A) receptors expressed in HEK293, NG108-15 and rat cerebellar granule neurons. European Journal of Neuroscience 24, 2504-2514 (2006). DOI ScienceOn |
8 | Johnston, G.A., GABAA receptor pharmacology. Pharmacology and Therapeutics 69, 173-198 (1996). DOI ScienceOn |
9 | Kim, J.W., Han, J.Y., Hong, J.T., Li, R., Eun, J.S., and Oh, K.W., Ethanol Extract of the Flower Chrysanthemum morifolium Augments Pentobarbital-Induced Sleep Behaviors: Involvement of Cl- Channel Activation. Evidence-based Complementary and Alternative Medicine: eCAM 2011 (2011). |
10 | Le Croueour, G., Thepenier, P., Richard, B., Petermann, C., Ghedira, K., and Zeches-Hanrot, M., Lotusine G: a new cyclopeptide alkaloid from Zizyphus lotus. Fitoterapia 73, 63-68 (2002). DOI ScienceOn |
11 | Lee, S.M., Park, J.G., Lee, Y.H., Lee, C.G., Min, B.S., Kim, J.H. et al., Anti-complementary activity of triterpenoides from fruits of Zizyphus jujuba. Biological and Pharmaceutical Bulletin 27, 1883-1886 (2004). DOI ScienceOn |
12 | Liu, J., Chen, B., and Yao, S., Simultaneous analysis and identification of main bioactive constituents in extract of Zizyphus jujuba var. sapinosa (Zizyphi spinosi semen) by high-performance liquid chromatography-photodiode array detection-electrospray mass spectrometry. Talanta 71, 668-675 (2007). DOI ScienceOn |
13 | Ma, Y., Han, H., Eun, J.S., Kim, H.C., Hong, J.T., and Oh, K.W., Sanjoinine A isolated from Zizyphi Spinosi Semen augments pentobarbital-induced sleeping behaviors through the modification of GABA-ergic systems. Biological and Pharmaceutical Bulletin 30, 1748-1753 (2007). DOI ScienceOn |
14 | Park, K.S., Oh, J.H., Yoo, H.S., Lee, Y.M., Lee, M.K., Hong, J.T. et al., (-)-Epigallocatechin-3-O-gallate (EGCG) reverses caffeine-induced anxiogenic-like effects. Neuroscience Letters 481, 131-134 (2010). DOI ScienceOn |
15 |
Ma, Y., Ma, H., Jo, Y.J., Kim, D.S., Woo, S.S., and Li, R., Honokiol potentiates pentobarbital-induced sleeping behaviors through |
16 | Murillo-Rodriguez, E., Arias-Carrion, O., Sanguino-Rodriguez, K., Gonzalez-Arias, M., and Haro, R., Mechanisms of sleep-wake cycle modulation. CNS Neurol Disord Drug Targets 8, 245-253 (2009). DOI ScienceOn |
17 | Park, J.H., Lee, H.J., Koh, S.B., Ban, J.Y., and Seong, Y.H., Protection of NMDA-induced neuronal cell damage by methanol extract of zizyphi spinosi semen in cultured rat cerebellar granule cells. Journal of Ethnopharmacology 95, 39-45 (2004). DOI ScienceOn |
18 | Sapin, E., Berod, A., Leger, L., Herman, P.A., Luppi, P.H., and Peyron, C., A very large number of GABAergic neurons are activated in the tuberal hypothalamus during paradoxical (REM) sleep hypersomnia. PLoS One 5, e11766 (2010). DOI ScienceOn |
19 | Suksamrarn, S., Panseeta, P., Kunchanawatta, S., Distaporn, T., Ruktasing, S., and Suksamrarn, A., Ceanothane- and lupane-type triterpenes with antiplasmodial and antimycobacterial activities from Ziziphus cambodiana. Chemical and Pharmaceutical Bulletin 54, 535-537 (2006). DOI ScienceOn |
20 | Vale, C., Fonfria, E., Bujons, J., Messeguer, A., Rodriguez-Farre, E., and Sunol, C., The organochlorine pesticides gamma-hexachlorocyclohexane (lindane), alpha-endosulfan and dieldrin differentially interact with GABA(A) and glycine-gated chloride channels in primary cultures of cerebellar granule cells. Neuroscience 117, 397-403 (2003). DOI ScienceOn |
21 | Wang, G.H., Jiang, Z.L., Fan, X.J., Zhang, L., Li, X., and Ke, K.F., Neuroprotective effect of taurine against focal cerebral ischemia in rats possibly mediated by activation of both GABAA and glycine receptors. Neuropharmacology 52, 1199-1209 (2007). DOI ScienceOn |
22 | Wang, L.E., Bai, Y.J., Shi, X.R., Cui, X.Y., Cui, S.Y., Zhang, F. et al., Spinosin, a C-glycoside flavonoid from semen Zizhiphi Spinozae, potentiated pentobarbital-induced sleep via the serotonergic system. Pharmacology, Biochemistry and Behavior 90, 399-403 (2008). DOI ScienceOn |
23 | Wu, X.Y., Zhao, J.L., Zhang, M., Li, F., Zhao, T., and Yang, L.Q., Sedative, hypnotic and anticonvulsant activities of the ethanol fraction from Rhizoma Pinelliae Praeparatum. Journal of Ethnopharmacology 135, 325-329 (2011). DOI ScienceOn |
24 | Wang, L.E., Cui, X.Y., Cui, S.Y., Cao, J.X., Zhang, J., Zhang, Y.H. et al., Potentiating effect of spinosin, a C-glycoside flavonoid of Semen Ziziphi spinosae, on pentobarbital-induced sleep may be related to postsynaptic 5-HT(1A) receptors. Phytomedicine 17, 404-409 (2010). DOI ScienceOn |
25 | West, M.R. and Molloy, C.R., A microplate assay measuring chloride ion channel activity. Analytical Biochemistry 241, 51-58 (1996). DOI ScienceOn |
26 | Winsky-Sommerer, R., Role of GABAA receptors in the physiology and pharmacology of sleep. European Journal of Neuroscience 29, 1779-1794 (2009). DOI ScienceOn |
27 | Yi, P.L., Lin, C.P., Tsai, C.H., Lin, J.G., and Chang, F.C., The involvement of serotonin receptors in suanzaorentang-induced sleep alteration. Journal of Biomedical Science 14, 829-840 (2007). DOI ScienceOn |
28 | Yi, P.L., Tsai, C.H., Chen, Y.C., and Chang, F.C., Gamma-aminobutyric acid (GABA) receptor mediates suanzaorentang, a traditional Chinese herb remedy, -induced sleep alteration. Journal of Biomedical Science 14, 285-297 (2007). DOI ScienceOn |
29 | Yoon, S.R., Jo, Y.J., Yang, S., Kim, Y.B., Nam, S.Y., Kim, H.C. et al., Sanjoinine A isolated from Semen Zizyphi Spinosi protects against kainic acid-induced convulsions. Archives of Pharmacal Research 32, 1515-1523 (2009). DOI ScienceOn |
30 | Zhang, M., Ning, G., Shou, C., Lu, Y., Hong, D., and Zheng, X., Inhibitory effect of jujuboside A on glutamate-mediated excitatory signal pathway in hippocampus. Planta Medica 69, 692-695 (2003). DOI ScienceOn |
31 | Zhang, M., Zhang, Y., and Xie, J., Simultaneous determination of jujuboside A, B and betulinic acid in semen Ziziphi spinosae by high performance liquid chromatography-evaporative light scattering detection. Journal of Pharmaceutical and Biomedical Analysis 48, 1467-1470 (2008). DOI ScienceOn |
![]() |